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Cardiovascular Physiological Phenomena

Cardiovascular Physiological Phenomena refers to the diverse range of biological processes and mechanisms that underlie the normal functioning of the cardiovascular system.
This includes the regulation of heart rate, blood pressure, vascular tone, and other essential cardiovascular parameters.
Understanding these phenomena is crucial for advancing cardiovascular research and developing effective treatments for related diseases.
PubCompare.ai's AI-driven platform empowers researchers to explore this complex field, locating the best protocols and products by comparing data across literature, pre-prints, and patents.
Leveraging AI-anaylsis, this powerful tool enhances reproducibility and research accruacy, enabling informed decisions that drive progress in cardiovasular science.

Most cited protocols related to «Cardiovascular Physiological Phenomena»

The first quantitative measurements of blood pressure were performed in animals by Hales in 1733 [24 , 25 (link)]. Early reports of intra-arterial pressure measurement in the human are from 1912, when Bleichröder [26 ] cannulated his own radial artery. It is unlikely that he recorded his BP although it would have been possible at that time: Frank developed accurate and fast manometers that could measure pulsatile pressure in 1903 [27 ]. Invasive measurement of BP was confined to the physiology labs for quite some time [28 (link), 29 (link)]. However in the 1950s and 1960s, with the development of refined insertion techniques [30 (link)] and Teflon catheters it became standard clinical practice. High fidelity catheter-tip manometers, such as used to measure pressure gradients across a coronary stenosis, were introduced by Murgo and Millar in 1972 [31 ]. Table 1 gives an overview of BP methods.

Methods for measurement of blood pressure and cardiac output

SystemMethodCompanyCOBP
NexfinFinger cuff technology/pulse contour analysisBMEYE+___+___
FinometerFinger cuff technology/pulse contour analysisFMS+___+___
LIFEGARD® ICGThoracic electrical bioimpedanceCAS Medical Systems, Inc.+___+
BioZ MonitorImpedance cardiographyCardioDynamics International Corporation+___+
Cheetah reliant“Bioreactance”Cheetah Medical+___+
Cardioscreen/NiccomoImpedance cardiography and impedance plethysmographyMedis Medizinische Messtechnik GmbH+___+
AESCULONElectrical “velocimetry”Osypka Medical GmbH+___+
HIC-4000Impedance cardiographyMicrotronics Corp Bio Imp Tech, Inc.+___
NICaSRegional impedanceNImedical+___
IQ23-dimensional impedanceNoninvasive Medical Technologies+___
ICONElectrical “velocimetry”Osypka Medical GmbH+___
PHYSIO FLOWThoracic electrical bioimpedanceManatec biomedical+___
AcQtracThoracic impedanceVäsamed+___
esCCOPulse wave transit timeNihon Kohden+___
TEBCOThoracic electrical bioimpedanceHEMO SAPIENS INC.+___
NCCOM 3Impedance cardiographyBomed Medical Manufacturing Ltd+___
RheoCardioMonitorImpedance cardiographyRheo-Graphic PTE+___
HemoSonic™ 100transesophageal DopplerArrow Critical Care Products+___
ECOMEndotracheal bioimpedanceConMed Corporation+___
CardioQ-ODM™Oesophageal DopplerDeltex+___
TECOTransesophageal DopplerMedicina+___
ODM IITransesophageal DopplerAbbott+___
HDI/PulseWave™ CR-2000Pressure waveform analysisHypertension Diagnostics, Inc+_ _+_ _
USCOM 1ATransthoracic DopplerUscom+_ _
NICORebreathing FickPhilips Respironics+
InnocorRebreathing FickInnovision A/S+
Vigileo/FloTracPulse contour analysisEdwards Lifesciences______
LiDCOplus PulseCOTranspulmonary lithium dilution/pulse contour analysisLiDCO Ltd______
PiCCO2Transpulmonary thermodilution/pulse contour analysisPULSION Medical Systems AG______
MOSTCARE PRAMPulse contour analysisVytech______
VigilancePulmonary artery catheter thermodilutionEdwards Lifesciences___
DDGDye-densitogram analyzerNihon Kohden
TruccomPulmonary artery catheter thermodilutionOmega Critical Care
COstatusUltrasound dilutionTransonic Systems Inc.+
CNAP Monitor 500Finger cuff technologyCNSystems Medizintechnik AG+___
SphygmoCor® CPV SystemApplanation tonometryAtCor Medical+_ _
TL-200 T-LINEApplanation tonometryTensys Medical, Inc.+_ _

+ noninvasive, – invasive, ___ continuous, _ _ semi-continuous, … intermittent

Practical noninvasive (intermittent) BP measurement became possible when Riva-Rocci presented his air-inflatable arm cuff connected to a manometer in 1896 [32 , 33 (link)]. By deflating the cuff and feeling for the pulse, systolic BP could be determined. In 1905 Korotkoff [34 , 35 (link)] advanced the technique further with the auscultatory method making it possible to determine diastolic pressure as well. In 1903 Cushing recommended BP monitoring using the Riva-Rocci sphygmomanometer for patients under general anesthesia [36 (link)]. Nowadays, automated assessment of BP with oscillometric devices is commonly used. These devices determine BP by analyzing the oscillations measured in the cuff-pressure. The pressure in the cuff is first brought above systolic pressure and then deflated to below diastolic pressure. Oscillations are largest when cuff pressure equals mean arterial pressure. Proprietary algorithms determine systolic and diastolic values from the oscillations. Oscillometers may be inaccurate [37 ], and provided values that are frequently lower than direct BP measurements in critically ill patients, [38 (link), 39 (link)] whereas detection of large BP changes is unreliable [40 (link)]. Due to its intermittent nature hyper- and hypotensive periods may be missed [2 (link)].
“Semi-continuous noninvasive methods” based on radial arterial tonometry require an additional arm cuff to calibrate arterial pressure [41 (link)–43 (link)]. The use of these devices may become problematic under conditions with significant patient motion or surgical manipulation of the limbs [43 (link), 44 (link)]. However, tonometry devices have contributed greatly to the knowledge of the relation between the pressure wave shape and cardiovascular function [45 (link), 46 (link)].
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Publication 2012
Animals Arteries Arteries, Radial Auscultation Cardiovascular Physiological Phenomena Catheters Cheetahs Coronary Stenosis Critical Care Critical Illness Determination, Blood Pressure Diagnosis Diastole Electricity Esophagus General Anesthesia Heart Homo sapiens Lithium Manometry Medical Devices Operative Surgical Procedures Oscillometry Patients physiology Pressure Pressure, Diastolic Pulse Rate Reliance resin cement Sphygmomanometers Systole Systolic Pressure Technique, Dilution Teflon Thermodilution Tonometry Velocimetry
Based on consensus between the authors, physical therapy interventions for the rehabilitation of patients with stroke were divided into: (1) interventions related to gait and mobility-related functions and activities, including novel methods focusing on efficient resource use, such as circuit class training and caregiver-mediated exercises; (2) interventions related to arm-hand activities; (3) interventions related to activities of daily living; (4) interventions related to physical fitness; and (5) other interventions which could not be classified into one of the other categories. In addition, attention was paid to (6) intensity of practice and (7) neurological treatment approaches.
The ICF [15] , [23] was used to classify the outcome measures into the following domains: muscle and movement functions (e.g. muscle power functions [b730], control of voluntary movement functions [b760], muscle tone functions [b735]), joint and bone functions (e.g. mobility of joint functions [b710]), sensory functions (e.g. proprioceptive function [b260], touch function [b365], sensory functions related to temperature and other stimuli [b720]), gait pattern functions [b770] (e.g. gait speed, stride length), functions of the cardiovascular and respiratory systems (e.g. heart functions [b410], blood pressure functions [b420], respiration functions [b440], respiratory muscle functions [b445], exercise tolerance functions [b455]), mental functions (e.g. quality of life, depression), balance (e.g. changing basic body position [d410], maintaining a body position [d415]), walking [d450] (e.g. distance, independence, falls), arm-hand activities (e.g. fine hand use [d440], hand and arm use [d445]), basic ADL (e.g. washing oneself [d510], toileting [d520], dressing [d540], eating [d550], urination functions [d620]), extended ADL (e.g. acquisition of goods and services [d620], preparing meals [d630], doing housework [d640], recreation and leisure [d920]), and attitudes (e.g. individual attitudes of immediate or extended family members, like caregiver strain [e410 and e425 respectively]). The primary outcomes were at the body functions and activities and participation levels, while secondary outcomes included contextual factors.
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Publication 2014
Attention Basal Bodies Blood Physiological Phenomena Bones Cardiovascular Physiological Phenomena Cerebrovascular Accident Exercise Tolerance Family Member Heart Human Body Joints Movement Muscle Tissue Muscle Tonus Patients Pressure Proprioception Range of Motion, Articular Rehabilitation Respiratory Physiology Respiratory System Strains Therapy, Physical Touch Urination

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Publication 2009
Cardiovascular Physiological Phenomena Females Heart isolation Microtus Nervous System, Autonomic Oxytocin Saline Solution TimeLine
The subjects were recruited from the Cardiac Aging Study (CAS), a prospective study initiated in 2014 that examines characteristics and determinants of cardiovascular function in elderly adults14 (link).
The current analysis is a cross-sectional analysis between left atrial function and metabolomics profiling obtained from subjects recruited from the CAS study. Subjects who had self-reported history of physician-diagnosed cardiovascular disease (such as coronary heart disease, atrial fibrillation and stroke) or cancer were excluded. A total of 128 participants were studied in this analysis. The SingHealth Centralised Institutional Review Board had approved the study protocol. Informed consent was obtained from all participants. All methods were performed in accordance with the relevant guidelines and regulations.
All participants were examined and interviewed on one study visit by trained study coordinators. Participants completed a standardized questionnaire that included medical history and coronary risk factors. Hypertension was defined by current use of antihypertensive drugs or physician-diagnosed hypertension. Diabetes mellitus was defined by current use of anti-diabetic agents or physician-diagnosed diabetes mellitus. Dyslipidemia was defined by current use of lipid-lowering agents or physician-diagnosed dyslipidemia. Smoking history was defined as ever smokers (former or current smoking) or never smokers. Body mass index was calculated as weight in kilograms divided by the square of height in meters. Sinus rhythm status was ascertained by resting electrocardiogram. Clinical data were obtained on the same day as assessment of cardiac magnetic resonance (CMR) imaging and serum collection.
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Publication 2018
Aged Antidiabetics Antihypertensive Agents Atrial Fibrillation Atrial Function, Left Cardiovascular Diseases Cardiovascular Physiological Phenomena Cerebrovascular Accident Diabetes Mellitus Dyslipidemias Electrocardiography Ethics Committees, Research Heart Heart Disease, Coronary High Blood Pressures Hypolipidemic Agents Index, Body Mass Malignant Neoplasms Physicians Serum Sinuses, Nasal
A high-frequency, high-resolution digital imaging platform with linear array technology and color Doppler mode for in vivo high-resolution micro-imaging was used for echocardiography (Vevo® 2100 Imaging System, FUJIFILM VisualSonics Inc., Toronto, Canada). For assessing cardiovascular function of mice a high-frequency transducer probe (VisualSonics MS400, FUJIFILM VisualSonics, Inc., Toronto, Canada with a frequency range of 18–38 MHz) was utilized as it provides appropriate resolution and depth of penetration needed. All echocardiograms were performed by one trained individual, and images were reviewed in conjunction with a clinical cardiologist and echocardiographer to ensure optimal image quality.
Both strains of mice were anesthetized with 2.5–3.0% (v/v) isoflurane mixed with room air. A second group of mice was studied in which isoflurane was mixed with 95% oxygen (v/v) to assess any effect of hypoxia on pulmonary valve hemodynamics. Mice were evaluated with a toe pinch to ensure a complete anesthesia. After achieving an adequate anesthesia, anthropomorphic measurements were taken. We measured the total body weight and nose to anus length, and secured mice on a prewarmed (37℃) imaging platform. About 2 mL of electrode gel is applied to each paw to connect them with electrocardiogram leads embedded in the imaging platform. Hairs from the ventral chest were removed by the use of commercially available hair removal cream (Nair™, Church & Dwight Co., Ewing, NJ, USA).
Mice were continuously monitored and isoflurane concentrations were titrated (1–3%) during imaging to maintain heart rate at 425 ± 50 beats per minute (bpm), compared to a basal heart rate of that is typically greater than 600 in active, conscious mice of both CD1 and C57BL/6 strains.12) (link) Isoflurane was used as this was shown to have the least effect on cardiac physiology in previous studies.12) (link) Heart rates less than 300 bpm are typically indicative of severe respiratory and cardiac depression, at which point anesthesia was stopped.7) (link) Heart rates greater than 500 bpm may indicate inadequate anesthesia. As with all anesthetics, isoflurane also decreases body temperature;13 (link)14) (link)15) (link) therefore a warming table is used to maintain core body temperature of 37℃.
The transducer probe was positioned on the mouse chest wall for imaging acquisition either by hand or by the use of a rail system. The advantages of handheld transducer probe imaging include speed and fine adjustments in changing the viewing angle (Fig. 1). The disadvantages of performing echocardiography holding the transducer probe are significantly longer training period to ensure reliable technique and reproducible imaging. The rail system requires less training and enhances reproducibility of imaging, therefore can be effectively utilized.
Our echocardiography protocol for assessing the right heart in mice is derived from contemporary clinical imaging guidelines written by the American Society of Echocardiography, endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology and the Canadian Society of Echocardiography.9) (link)
Publication 2016
Anesthesia Anesthetics Anus Body Temperature Body Weight Cardiologists Cardiovascular Physiological Phenomena Cardiovascular System Chest Consciousness Depilation Echocardiography Electrocardiography Europeans Hair Heart Hemodynamics Hypoxia Isoflurane Menstruation Disturbances Mus Nose Oxygen physiology Rate, Heart Respiratory Rate Strains Transducers Valves, Pulmonary Wall, Chest

Most recents protocols related to «Cardiovascular Physiological Phenomena»

This investigation was conducted in the Laboratory for cardiovascular physiology of the Faculty of Medical Sciences, University of Kragujevac, Serbia. The study protocol was approved by the Ethical Committee for the welfare of experimental animals of the Faculty of Medical Sciences, University of Kragujevac, Serbia. All experiments were performed following ARRIVE guidelines 2.0 for reporting animal research.
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Publication 2023
Animals Cardiovascular Physiological Phenomena Faculty Faculty, Medical

A robust battery of standardised assessments of cardiovascular function, respiratory function, physical function including hand grip strength, balance, walk speed, visual health, hearing and cognitive health were used, all of which are comparable to those used in other longitudinal studies internationally. Other standard clinical measures including blood pressure, height, weight, and hip and waist circumference were also collected. Non-fasting blood and urine samples were also obtained as part of the health assessment. If glucose or lipid results were outside the normal expected range, then both the participant and participant’s General Practitioner were informed in writing. The assessment methods and their rationale for inclusion in the health assessment are detailed below.
Table 1 provides an overview of the physical, cognitive health, mental health, dietary assessment measures and biological samples measures included in the health assessment and compares the measures to other comparative longitudinal studies of ageing. While many of these measures are described in detail, a comprehensive description of the protocols used is beyond the remit of this article. Further manuscripts detailing specific strands of research being conducted within NICOLA that are not included in this manuscript will be forthcoming including the results from the analysis of the Wave 1 dietary questionnaire.

Measures used in the NICOLA health assessment compared to other similar longitudinal studies of ageing

Outcome MeasureType of assessmentMeasuresComparative study
Physical HealthAnthropometric

Weight

Height

Waist and hip circumference

TILDA, ELSA
Body compositionBodystat (% body fat)None
Cardiovascular

Blood pressure

Orthostatic blood pressure

TILDA, ELSA
RespiratorySpirometryELSA
Mobility and strength

Step test

Timed up and go

Grip strength (dynamometry)

TILDA, ELSA
Vision

Visual acuity

Multi-modal retinal imaging

TILDA (visual acuity)
Facial photographPhysical attractiveness / signs of ageingNone
Cognitive HealthCognitive function

MMSE

MOCA

Colour trails 2

Animal recall

TILDA
Dietary Intake*Food frequency questionnaire

Dietary intake (EPIC-FFQ)

Special diets

Cooking and food shopping

Food supplements / vitamins

ELSA (Wave 9 only, online FFQ (Oxford-WebQ))
Mental Health

Mental well-being

Depression

Warwick-Edinburgh Mental Well-Being Scale (WEMWBS)

Centre for Epidemiologic Studies Depression Scale (CES-D)

None

ELSA

Biological SamplesBlood and urine sample (non-fasting)

Lipid profile

Genomic biomarkers

Dietary biomarkers

Bone markers

Inflammatory markers

Other biomarkers

TILDA, ELSA

* Not detailed in this paper

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Publication 2023
Biopharmaceuticals BLOOD Blood Pressure Body Fat Cardiovascular Physiological Phenomena Cognition Diet Dietary Supplements Eating Face Food Glucose Lipids Physical Examination Respiration Retina TNFSF10 protein, human Urine Visual Acuity Waist Circumference
The intervention was any form of short-term heat acclimation that were equal to or longer than four [13 (link)], but no more than twelve HA days, as this is the latest time that a heatwave can be accurately predicted via a weather report [11 (link)]. The specific outcome measures being assessed were those conducive to generating heat adaptive responses that can be considered desirable for protection against heat waves either being physiological such as any cardiovascular measures or psychological e.g., reduced perception of fatigue [20 (link)]. The final articles were reviewed to assess if any adverse events were reported, this is in the interest of feasibility and safety for future protocols. No restrictions on the timeframe of publication were implemented and only peer-reviewed studies using primary empirical data were eligible.
All included studies were assessed for methodologic quality and risk of bias. The included studies were subject to a modified Downs and Black (1998) checklist to assess the overall quality of the papers and rank them accordingly [36 (link)–38 (link)]. The modified checklist uses an altered scoring system for item 27 that refers to the power of the study [37 (link)–39 (link)]. Accordingly, the maximum score for item 27 was reduced from five to one thus the highest possible score for the checklist was twenty-seven. Downs and Black (1998) score ranges were given corresponding quality levels as previously reported [37 (link)]: excellent (26–28); good (20–25); fair (15–19); and poor (<14).
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Publication 2023
Acclimatization Cardiovascular Physiological Phenomena Fatigue Infrared Rays Lanugo Safety Thermotolerance
Occlusion has a significant effect on the characteristics of pulse waves at the carotid artery. However, these characteristics may also be influenced by several factors such as the condition of the patient. To understand the relationship between occlusion and the characteristics of pulse waves, other contributing factors were precluded from this study. For example, prior to commencing the measurements, all subjects avoided eating, exercising, and smoking for over 2 h. This was followed by resting in the supine position for 15 min in a quiet room at 25 °C. The cardiovascular function and vasomotor tone in the resting conditions were thus obtained19 (link),20 (link).
The schematic of the measurement condition is illustrated in Fig. 3. The pulse wave was measured at the skin surface by placing a piezoelectric ceramic transducer (MA40E7R, Murata Corp.) at the upper edge of the thyroid cartilage, the position where the strongest pulse wave could be sensed by a finger. We measured pulse waves in both the right and left common carotid arteries. The observed signal was amplified by 40 dB using a preamplifier (NF 5307) and was subsequently digitized using a 14-bit analog-to-digital converter (Keyence NR-500, NR-HA08, or using our prototype measurement system manufactured in collaboration with Proassist. Ltd.) with a sampling frequency of 1.0 kHz21 (link). In accordance with the characteristics of the sensor and the circuit system, the measured pulse wave corresponded to the differential (velocity) waveform in the low-frequency range. Thereafter, an average of the observed waves was obtained, and the DC component was eliminated to obtain the averaged differential pulse waveforms. Differential pulse waves (not integrated pulse waves) were consistently used in the measurement, feature extraction, and classification of the proposed method. Hereinafter, we use the word "pulse wave" to indicate "differential pulse wave" for simplicity.

Pulse wave measurement.

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Publication 2023
Cardiovascular Physiological Phenomena Common Carotid Artery Dental Occlusion Patients Pulse Rate Skin Thyroid Cartilage Transducers
Seven candidate microRNAs were selected from the discovery phase, based on statistical significance, log fold change, and known biological functions from the cardiovascular literature. Selected microRNAs were measured using reverse-transcription quantitative polymerase chain reaction (RT-qPCR) in all patients with cardiovascular death (n = 42), labeled as cases, as well as their age- and sex-matched controls (n = 55). Matching was performed in a 1:2 ratio with replacement; therefore, the same control could be matched to several cases.
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Publication 2023
Biopharmaceuticals Cardiovascular Physiological Phenomena Cardiovascular System MicroRNAs Patients Reverse Transcriptase Polymerase Chain Reaction

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More about "Cardiovascular Physiological Phenomena"

Cardiovascular Physiological Phenomena encompass the diverse range of biological processes and mechanisms that underlie the normal functioning of the cardiovascular system.
This includes the regulation of heart rate, blood pressure, vascular tone, and other essential cardiovascular parameters.
Understanding these cardiovascular phenomena is crucial for advancing research and developing effective treatments for related diseases.
Researchers can explore this complex field using PubCompare.ai's AI-driven platform, which empowers them to locate the best protocols and products by comparing data across literature, pre-prints, and patents.
Leveraging AI-analysis, this powerful tool enhances reproducibility and research accuracy, enabling informed decisions that drive progress in cardiovascular science.
Key subtopics within Cardiovascular Physiological Phenomena include cardiac hemodynamics, vascular physiology, autonomic control of the cardiovascular system, and cardiovascular responses to exercise, stress, and other physiological stimuli.
Relevant methodologies and technologies used in this field include radiotelemetry, Vevo 2100 and Vevo 3100 imaging systems, Stockert 70 radiofrequency generators, and Kubios heart rate variability analysis software.
Pharmacological agents such as phenylephrine and propofol are commonly used to study cardiovascular responses in animal models.
Statistical analysis tools like Statistica v. 13 can also be employed to analyze and interpret the data gathered from these experiments.
By incorporating these insights and tools, researchers can enhance the reproducibility and accuracy of their cardiovascular research, ultimately driving progress in this vital field of study.