Regional Centers were selected in a competitive process in which universities and other research institutions were invited to submit proposals for covered areas and population, recruitment methods, organization structures, regional liaison, and the resources. Each Regional Center consists of one or more study areas. The population of the selected study areas is 130,000 to 600,000. Assuming birth rate of the study areas to be 1%, each Regional Center will see 1,300 to 6,000 annual births, 4,400 on average. JECS aims half of all the births in the area to be covered. Selected Regional Centers are required to recruit 3,000 to 9,000 pregnant women in three years, totaling to 100,000 participants in 15 Regional Centers (Figure
Birth Weight
It is an important indicator of an infant's health and a critical factor in determining appropriate medical care and monitoring.
This MeSH term encompasses data and research related to factors that can influence birth weight, such as maternal health, gestational age, and environmental conditions.
Researchers can use PubCompare.ai to streamline their birth weight studies, comparing protocols and data across literature, preprints, and patents to uncover insights and optimze their research more efficently.
Most cited protocols related to «Birth Weight»
Regional Centers were selected in a competitive process in which universities and other research institutions were invited to submit proposals for covered areas and population, recruitment methods, organization structures, regional liaison, and the resources. Each Regional Center consists of one or more study areas. The population of the selected study areas is 130,000 to 600,000. Assuming birth rate of the study areas to be 1%, each Regional Center will see 1,300 to 6,000 annual births, 4,400 on average. JECS aims half of all the births in the area to be covered. Selected Regional Centers are required to recruit 3,000 to 9,000 pregnant women in three years, totaling to 100,000 participants in 15 Regional Centers (Figure
a) Corrected gestational ages through fetal ultrasound and/or infant assessment and/or statistical correction;
b) Data percentiles at 24 weeks gestational age or lower;
c) Sample of at least 25,000 babies, with more than 500 infants aged less than 30 weeks;
d) Separate data on females and males;
e) Data available numerically in published form or from authors,
f) Data collected within the past 25 years (1987 to 2012) to account for any secular trends.
The effect of different background correction methods on measurement accuracy was assessed using data from methylation control mixture samples for this same study (12 (link)), where purified human 100% methylated and unmethylated DNA (Zymo Research, Irving CA) were mixed together in different proportions to create laboratory control samples with specific methylation levels: 0%, 5%, 10%, 20%, 40%, 50%, 60%, 80% and 100% methylated Replicates for each methylation level (n = 10, 3, 2, 3, 3, 2, 3, 3 and 10, respectively) were independently assayed on different arrays.
To avoid possible impact on evaluations, we excluded 69 075 probes, which include non-specific bind probes, common (MAF > 0.05) SNPs at CpG target regions, probes on sex chromosomes and probes with multimodal methylation distributions identified using ENmix R package. We also excluded probes with low quality methylation values where the number of beads was less than 3 or detection P-value greater than 0.05.
To demonstrate the effect of ENmix background correction method on epigenome-wide association studies (EWAS), we re-analyzed raw blood DNA methylation data from 889 infants in relation to maternal smoking (12 (link)). We preprocessed the data with different methods or combinations of methods: raw data, Q5 background correction, ENmix_oob background correction, ENmix and dye bias correction (ENmixD), ENmix+dye bias correction+quantile normalization (ENmixDQ) and ENmix+dye bias correction+quantile normalization+BMIQ (ENmixDQB). We used a robust linear regression model to test for association between maternal smoking and infant DNA methylation level adjusting for the following variables: cell type proportion (CD8T, CD4T, NK, Bcell, Mono and Gran) estimated using the Houseman method (13 (link)) from minfi R package, gestational age in weeks, sex, education in two categories, birth weight, maternal age, maternal BMI, parity, experimental batch, cleft phenotype and baby birth year.
To improve on the Babson graph, two types of data were needed: infant size measured at the time of birth for the intrauterine section and term infant measurements for the post-term section. Population studies with large sample sizes were preferred to improve generalizability. The World Health Organization has recommended that gestational age of infants be described as completed weeks [7 (link)], so data stated in this manner were favored. Numerical data were preferred over graphic depiction to ensure accuracy.
In many cases, exposure data were available for the reference method of ascertainment and for alternative methods, such as tobacco surveys reporting daily smoking versus total smoking; in these cases, we estimated the statistical relationship between the reference and alternative methods of ascertainment using network meta-regression and corrected the alternative data using this relationship.
Most recents protocols related to «Birth Weight»
Example 21
There is growing evidence that bisphenol A (BPA) may adversely affect humans. BPA is an endocrine disruptor that has been shown to be harmful in laboratory animal studies. As reported by Rochester J (Reproductive Toxicology, 2013) BPA has been shown to affect many endpoints of fertility, including poor ovarian response, viability of oocytes, and reduced yield of viable oocytes. BPA has also been correlated with PCOS, endometrial disorders, an increased rate of miscarriages, premature delivery, and lower birth weights.
Current methods of detecting BPA in blood are done through mass spectrometry. Monitoring of BPA levels in blood may help reduce or eliminate certain sources of BPA in a women's environment, aiding in overall health.
In some embodiments the disclosed device focuses on detecting levels of BPA toxin from menstrual blood or cervicovaginal fluid.
The control group included randomly recruited healthy parturients with uncomplicated pregnancies, who came, during 2020, to the hospital for a routine screening hearing test for their newborns in the neonatal clinic, during postpartum period, on days 2–11.
.Data were collected by electronic medical record review and included: maternal age, gravity and parity, characteristics of current pregnancy (gestational age at delivery, mode of delivery, neonatal birth weight) and hemoglobin level on the day of labor. The postpartum hospitalization data included postpartum day of readmission and clinical features on presentation including pulse rate (beat per minute, bpm), blood pressure and serum laboratory values of liver function and platelet count. Pulse rate (bpm) and blood pressure of the control group were measured after at least 10 min of rest in a sitting position.
The study was approved by the Meir Medical Center Institutional Review Board on 17th March 2020, number MMC-0048–20. All methods were carried out in accordance with relevant guidelines and regulations. Informed consent was not obtained from subjects due to the study nature.
In order to study the association between GDM and preterm birth among vAMA women, we established three models, and odds ratios (ORs) with 95% confidence intervals (CIs) were estimated. Model 1 was a univariate model. Model 2 was a multivariate model adjusting for maternal age at delivery, race, education, and newborn sex. Then all variables were included in a multivariable model for stepwise regression, and the following variables were adjusted for in Model 3: maternal age at delivery, race, education, newborn sex, pre-pregnancy weight, pre-pregnancy BMI, delivery weight, weight gain, smoking before pregnancy, hypertension eclampsia, gestational hypertension, pre-pregnancy hypertension, number of prenatal visits, plurality, total birth order, prior birth now living, prior other terminations, birth weight, pregnancy method, and method of delivery. Subgroup analyses were then performed based on race and use of infertility treatment to demonstrate if and how the association between GDM and preterm birth in vAMA women varied by race and use of infertility treatment. Further, preterm birth was subdivided into extremely preterm, very preterm, and moderate or late preterm birth. Logistic regression was used to investigate the association between GDM and different stages of preterm birth. Model 1 was a univariate model. Model 2 was a multivariate model correcting for maternal age at delivery, race, education, and newborn sex. Model 3 was a multivariate model correcting for maternal age at delivery, race, education, newborn sex, delivery weight, smoking status 2nd trimester, hypertension eclampsia, gestational hypertension, pre-pregnancy hypertension, number of prenatal visits, WIC, plurality, prior other terminations, total birth order, birth weight, pregnancy method, and method of delivery. As for the associations of GDM with NICU admission, low birthweight and small for gestational age in vAMA women, analytical methods were the same as those for the association between GDM and preterm birth, and subgroup analyses by race and use of infertility treatment were also conducted for these outcomes.
All statistical analyses were two-sided, and P < 0.05 was considered to be statistically significant. All analyses were completed by SAS 9.4 software (SAS Institute Inc., Cary, NC, USA).
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More about "Birth Weight"
This key measurement, recorded at the time of delivery, serves as a critical factor in determining appropriate medical care and monitoring for newborns.
Researchers studying birth weight can leverage a wealth of data and research related to various factors that can influence this important indicator, such as maternal health, gestational age, and environmental conditions.
To streamline and optimize their birth weight studies, researchers can utilize PubCompare.ai, a leading AI-driven platform that enables the comparison of protocols and data across literature, preprints, and patents.
This powerful tool can help uncover valuable insights and enhance the efficiency of birth weight research, whether it's conducted using statistical software like SAS version 9.4, SPSS version 20, Stata 14, or other popular packages.
By comparing data and protocols from a vast array of sources, including SAS 9.4, SPSS version 22.0, and Stata 13, researchers can identify the most effective and reproducible approaches, ultimately leading to more robust and insightful findings.
PubCompare.ai's AI-driven comparisons empower researchers to streamline their studies, accelerate their discovery process, and optimize their birth weight research for maximum impact.
Whether you're exploring the influence of maternal health, investigating gestational age factors, or delving into environmental conditions that can impact birth weight, PubCompare.ai is the go-to tool to enhance your research efficiency and uncover valuable insights that can advance our understanding of this critical indicator of infant well-being.
Embark on your birth weight research journey with confidence and ease, leveraging the power of PubCompare.ai to drive your studies forward.