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Bronchoscopy

Bronchoscopy is a medical procedure in which a flexible, lighted tube (bronchoscope) is inserted through the nose or mouth and into the lungs to examine the airways.
This procedure allows healthcare providers to diagnose and treat various lung conditions, such as infections, cancer, and airway blockages.
Bronchoscopy can also be used to obtain samples of lung tissue or fluid for further analysis.
The procedure is generally well-tolerated, though patients may experience some discomfort or a temporary sore throat.
Proper preparation and anesthesia help ensure patient comfort and safety during the bronchoscopy.
This minimally invasive technique provides critical information to guide the management of respiratory disorders and is an essential tool in pulmonary medicine.

Most cited protocols related to «Bronchoscopy»

The Difficult Airway Society commissioned a working group to update the guidelines in April 2012. An initial literature search was conducted for the period January 2002 to June 2012 using databases (Medline, PubMed, Embase, and Ovid) and a search engine (Google Scholar). The websites of the American Society of Anesthesiologists (http://www.asahq.org), Australian and New Zealand College of Anaesthetists (http://www.anzca.edu.au), European Society of Anesthesiologists' (http://www.esahq.org/euroanaesthesia), Canadian Anesthesiologists' Society (http://www.cas.ca), and the Scandinavian Society of Anesthesiology and Intensive Care Medicine (http://ssai.info/guidelines/) were also searched for airway guidelines. English language articles and abstract publications were identified using keywords and filters. The search terms were as follows: ‘Aintree intubating catheter’, ‘Airtraq’, ‘airway device’, ‘airway emergency’, ‘airway management’, ‘Ambu aScope’, ‘backward upward rightward pressure’, ‘Bonfils’, ‘Bullard’, ‘bronchoscopy’, ‘BURP manoeuvre’, ‘can't intubate can't ventilate’, ‘can't intubate can't oxygenate’, ‘C-Mac’, ‘Combitube’, ‘cricoid pressure’, ‘cricothyroidotomy’, ‘cricothyrotomy’, ‘C trach’, ‘difficult airway’, ‘difficult intubation’, ‘difficult laryngoscopy’, ‘difficult mask ventilation’, ‘difficult ventilation’, ‘endotracheal intubation’, ‘esophageal intubation’, ‘Eschmann stylet’, ‘failed intubation’, ‘Fastrach’, ‘fiber-optic scope’, ‘fibreoptic intubation’, ‘fiberoptic scope’, ‘fibreoptic stylet’, ‘fibrescope’ ‘Frova catheter', ‘Glidescope’, ‘gum elastic bougie’, ‘hypoxia’, ‘i-gel’, ‘illuminating stylet’, ‘jet ventilation catheter’, ‘laryngeal mask’, ‘laryngeal mask airway Supreme’, ‘laryngoscopy’, ‘lighted stylet’, ‘light wand’, ‘LMA Supreme’, ‘Manujet’, ‘McCoy’, ‘McGrath’, ‘nasotracheal intubation’, ‘obesity’, ‘oesophageal detector device’, ‘oesophageal intubation’, ‘Pentax airway scope’, ‘Pentax AWS’, ‘ProSeal LMA′, ‘Quicktrach’, ‘ramping’, ‘rapid sequence induction’, ‘Ravussin cannula’, ‘Sanders injector’, ‘Shikani stylet’, ‘sugammadex’, ‘supraglottic airway’, ‘suxamethonium’, ‘tracheal introducer’, ‘tracheal intubation’, ‘Trachview’, ‘Tru view’, ‘tube introducer’, ‘Venner APA’, ‘videolaryngoscope’, and ‘videolaryngoscopy’.
The initial search retrieved 16 590 abstracts. The searches (using the same terms) were repeated every 6 months. In total, 23 039 abstracts were retrieved and assessed for relevance by the working group; 971 full-text articles were reviewed. Additional articles were retrieved by cross-referencing the data and hand-searching. Each of the relevant articles was reviewed by at least two members of the working group. In areas where the evidence was insufficient to recommend particular techniques, expert opinion was sought and reviewed.8 (link) This was most notably the situation when reviewing rescue techniques for the ‘can't intubate can't oxygenate’ (CICO) situation.
Opinions of the DAS membership were sought throughout the process. Presentations were given at the 2013 and 2014 DAS Annual Scientific meetings, updates were posted on the DAS website, and members were invited to complete an online survey about which areas of the existing guidelines needed updating. Following the methodology used for the extubation guidelines,5 (link) a draft version of the guidelines was circulated to selected members of DAS and acknowledged international experts for comment. All correspondence was reviewed by the working group.
Publication 2015
Airway Management Anesthesiologist Anesthetist Bronchoscopy Cannula Catheters Dyspnea Emergencies Eructation Esophagus Europeans Frova Hypoxia Intensive Care Intubation Intubation, Intratracheal Laryngoscopy Light Medical Devices Obesity Pharmaceutical Preparations Pressure Rapid Sequence Induction Scandinavians Succinylcholine Sugammadex Trachea Tracheal Extubation
Eligible studies included health technology assessments (HTAs), systematic reviews, meta-analyses, randomized controlled trials, and non-randomized studies. The study population involved HCWs caring for patients with acute respiratory infections. The intervention was the provision of care to patients undergoing aerosol generating procedures (exposed to the procedures). The comparator was the provision of care to patients not undergoing aerosol generating procedures (unexposed to the procedures). The outcome of interest was the risk of transmission of acute respiratory infections from patients to HCWs. Procedures that might promote the generation of droplets or aerosols (non-exhaustive list) included non-invasive ventilation (CPAP and BiPAP), endotracheal intubation, airway suctioning, high frequency oscillatory ventilation, bag-valve mask ventilation, chest physiotherapy, nebulizer therapies, aerosol humidification, bronchoscopy or other upper airway endoscopy, tracheotomy, and open thoracotomy.
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Publication 2012
Biphasic Continuous Positive Airway Pressure Bronchoscopy Chest Continuous Positive Airway Pressure Endoscopy High-Frequency Oscillation Ventilation Intubation, Intratracheal Nebulizers Noninvasive Ventilation Patients Respiratory Tract Infections Technology Assessment, Biomedical Therapy, Physical Thoracotomy Tracheotomy Transmission, Communicable Disease
Over an 18 month period, discarded tissue from 3 chemo-naive SCLC patients undergoing therapeutic bronchoscopy for acute bronchial obstruction was obtained fresh and transported to the laboratory in 1X PBS at 4°C. All samples were anonymized, and obtained in accordance with the Johns Hopkins University Institutional Review Board. Due to the small amount of material available, the entire sample was used to generate a xenograft. Under aseptic conditions, tumor samples were finely minced with razor blades, vigorously triturated in 1XPBS, passed through a 60μm filter, centrifuged and then resuspended in 500μl of Matrigel (BD Biosciences) at 4°C. Cells were then injected subcutaneously in the flanks of 5 NOD/SCID mice that were monitored for tumor growth. When the P0 tumors reached 1cm in diameter, the mouse was sacrificed and the tumor divided into sections for snap freezing, frozen section, formalin fixation, conventional cell culture or serial passage. All animal studies were performed in accordance with protocols approved by the Johns Hopkins University Animal Care and Use Committee.
Serial passage in vivo was performed by disaggregating the tumor as described above. Aliquots of cells were then injected into the flanks of athymic nude mice in Matrigel, or cryopreserved in 90% RPMI (Invitrogen)/10% DMSO (Sigma). Conventional cell lines were established by seeding an aliquot of disaggregated cells in culture with Advanced RPMI (Invitrogen)/1% Bovine Calf Serum (Invitrogen). Cell lines were passaged and cryopreserved in standard fashion for SCLC cultures. Publically available SCLC cell lines were obtained from ATCC and cultured in Advanced RPMI (Invitrogen)/1% Bovine Calf Serum. Xenografts derived from these conventional cell lines were grown in the flanks of nude mice as described above. Orthotopic xenografts were generated by dorsoscapular, transcutaneous injection of cells suspended in Matrigel into the right lung of nude mice, essentially as described (12 (link)).
Publication 2009
Animals Asepsis Bos taurus Bronchi Bronchoscopy Cell Culture Techniques Cell Lines Cells Cryoultramicrotomy Ethics Committees, Research Formalin Heterografts Lung matrigel Mice, Inbred NOD Mice, Nude Mus Neoplasms Patients SCID Mice Serum Small Cell Lung Carcinoma Sulfoxide, Dimethyl Therapeutics Thymic aplasia Tissues
All subjects were recruited from the Respiratory Medicine Unit of the ‘Fondazione Salvatore Maugeri’ (Veruno, Italy), the Section of Respiratory Diseases of the University Hospital of Ferrara, Italy and the Section of Respiratory Diseases of the University Hospital of Katowice, Poland for immunohistochemistry and ELISA experiments. The severity of the airflow limitation, as determined by spirometry, was graded using Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria.19 (link) All former smokers had stopped smoking for at least 1 year. COPD and chronic bronchitis were defined, according to international guidelines: COPD, presence of a post-bronchodilator forced expiratory volume in 1s (FEV1)/forced vital capacity ratio <70%; chronic bronchitis, presence of cough and sputum production for at least 3 months in each of two consecutive years (http://www.goldcopd.com). All patients with COPD were stable. The study conformed to the Declaration of Helsinki. We obtained and studied bronchial biopsies from 55 subjects: 32 had a diagnosis of COPD in a stable clinical state,20 (link) 12 were current or ex-smokers with normal lung function, and 11 were non-smokers with normal lung function (table 1). The smoking history was similar in the three smoker groups: mild/moderate and severe/very severe COPD, and healthy smokers with normal lung function. Clinical details of the patients in whom BAL was collected are summarised in table 2. The results provided are the data from 26 patients with COPD and 18 control smokers with normal lung function. Due to the necessity to concentrate the BAL supernatants the results provided for each ELISA are the data from 15 patients with COPD and 14 control smokers with normal lung function which are not the same patients for all mediators measured.
A detailed description of subjects, lung function tests, fibreoptic bronchoscopy and processing of bronchial biopsies and BAL, immunohistochemistry, scoring system for immunohistochemistry, double staining and confocal microscopy, ELISA tests performed on the BAL fluid and ‘in vitro’ experiments performed on normal human bronchial epithelial (NHBE) cells and details of statistical analysis are provided in the online supplementary data repository.
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Publication 2014
Biopsy Bronchi Bronchitis, Chronic Bronchodilator Agents Bronchoscopy Chronic Obstructive Airway Disease Cough Diagnosis Enzyme-Linked Immunosorbent Assay Epithelial Cells Ex-Smokers Gold Homo sapiens Immunohistochemistry Microscopy, Confocal Non-Smokers Patients Respiration Disorders Respiratory Physiology Spirometry Sputum Tests, Pulmonary Function Vital Capacity Volumes, Forced Expiratory
We defined hospitalists as physicians in general internal medicine who had at least five evaluation-and-management billings in a given year and generated at least 90% of their total evaluation-and-management billings in the year from services to hospital inpatients (Fig. 1). Since our source of data is a 5% sample, these five evaluation-and-management billings represent 100 or more charges to Medicare patients. Using inpatient evaluation-and-management billing codes (Current Procedural Terminology [CPT] codes 99221–99223, 99231–99233, and 99251–99255) and outpatient evaluation-and-management billing codes (CPT codes 99201–99205, 99211–99215, and 99241–99245), we calculated the percentage of each physician’s evaluation-and-management claims that were generated from services provided to hospitalized patients.
We analyzed the effect of different cutoff points according to the percentage of evaluation-and-management charges generated from care provided to hospitalized patients (≥80% vs. ≥90%) and according to the minimum number of evaluation-and-management charges in a given year in the 5% sample of Medicare data (≥5 vs. ≥10) in the algorithm to identify hospitalists. We tested the algorithm in a validation set of 57 hospitalists and 172 physicians in traditional non–hospital-based general internal medicine (hereafter referred to as nonhospitalists) employed in 2006 at seven hospitals. These hospitals were located in California (University of California, Los Angeles, Medical Center), Michigan (Wayne State University Detroit Medical Center), Virginia (Hospital Corporation of America [HCA]–affiliated hospitals in Richmond, including Henrico Doctors’ Hospital, John Randolph Medical Center, HCA Retreat Hospital, Johnston Willis Hospital, and Chippenham Hospital), Wisconsin (Sinai Samaritan Medical Center), and Texas (University of Texas Medical Branch, Clear Lake Regional Medical Center, and University of Texas Health Science Center at San Antonio). The algorithm requiring a minimum of 5 evaluation-and-management charges per physician in a given year and the algorithm requiring 10 or more such charges, with both requiring that 90% or more of the charges represent the care of hospitalized patients, had a sensitivity of 84.2% and 71.9%, a specificity of 96.5% and 97.1%, and a positive predictive value of 88.9% and 89.1%, respectively. The algorithm requiring 5 or more evaluation-and-management charges and the algorithm requiring 10 or more such charges, with both requiring that 80% or more of the charges represent the care of hospital inpatients, had a sensitivity of 87.7% and 73.7%, a specificity of 93.0% and 94.2%, and a positive predictive value of 80.6% and 80.8%, respectively. The sensitivities of the four algorithms were very similar (91.1%, 88.9%, 91.1%, and 88.9%, respectively) when applied to 45 hospitalists in two hospitalist groups serving community hospitals in the Houston and Austin metropolitan areas. We selected the algorithm requiring at least five evaluation-and-management charges with at least 90% of such charges generated from the care of hospital inpatients because the sensitivity (84.2%) and positive predictive value (88.9%) were acceptable.
We also evaluated the specificity of the algorithm by assessing whether hospitalists in general internal medicine identified by the algorithm submitted claims for procedures that are not usually performed by general internists; these procedures included colonoscopy, upper endoscopy, liver biopsy, hemodialysis, peritoneal dialysis, kidney biopsy, bronchoscopy, and cardiac catheterization. In 1995, the proportion of physicians identified as hospitalists who billed for one or more of these procedures was 14.9%; this percentage decreased to 2.3% in 2006. In some analyses, we also calculated the percentage of physicians in other specialties for whom more than 90% of evaluation-and-management billing codes were generated from services provided to hospitalized patients.
Publication 2009
austin Biopsy Bronchoscopy Catheterizations, Cardiac Colonoscopy Endoscopy Hemodialysis Hospitalists Hospitalization Hypersensitivity Inpatient Kidney Liver Outpatients Patients Peritoneal Dialysis Physicians

Most recents protocols related to «Bronchoscopy»

The following data were recorded during the preoperative examination: Sex, age, height, body weight, BMI, smoking history, complete blood count (leukocytes, hemoglobin, platelets), liver function tests (liver enzymes, albumin), renal function tests, preoperative oxygen saturation, history of previous surgery, and concomitant diseases (type 2 diabetes, hypertension, pulmonary and cardiac diseases).
The following data were also collected: History and physical examination findings, chest radiographs, computed tomographic examinations of the chest (CT), electrocardiography (ECG) and echocardiography (if required), pulmonary function test results (forced expiratory volume (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio), and arterial blood gases. In patients with lung cancer, the type and stage of malignancy were determined, and flexible bronchoscopy was performed.
During the intraoperative process, the type of endotracheal tube, the duration of anesthesia and surgery, the surgical procedure (VATS, thoracotomy, mediastinoscopy, and others) performed, and complications that required intraoperative treatment were also noted.
PPCs have been defined as complications that occur in the postoperative period and cause clinical conditions.
Publication 2023
Albumins Anesthesia Arteries Blood Gas Analysis Blood Platelets Body Weight Bronchoscopy Chest Complete Blood Count concomitant disease Diabetes Mellitus, Non-Insulin-Dependent Echocardiography Electrocardiography Enzymes Exhaling Forced Vital Capacity Heart Diseases Hemoglobin High Blood Pressures Kidney Function Tests Leukocytes Liver Liver Function Tests Lung Lung Cancer Mediastinoscopy Operative Surgical Procedures Oxygen Saturation Patients Physical Examination Radiography, Thoracic Staging, Cancer Tests, Pulmonary Function Thoracic Surgery, Video-Assisted Thoracotomy Training Programs Volumes, Forced Expiratory X-Ray Computed Tomography
The seven adult marmosets were inoculated endobronchially at the level of the main carina using a special narrow diameter bronchoscope with one mL of a 108 CFU/mL M. intracellulare obtained from the Mycobacteria/Nocardia Research Laboratory at the UTHSCT. All procedures (bronchoscopy, blood draws and euthanasia) were conducted under ketamine anesthesia with the additional use of isoflurane anesthesia with bronchoscopy and bronchoalveolar lavage (BAL) in the presence of veterinary staff. Each animal underwent assessment of serum chemistry, and complete blood count prior to inoculation and on the day of euthanasia. Because there are no previous comparable studies with this primate, we sacrificed a group of animals at 30 days and another group at 60 days to optimize the chance of recovering M. intracelluare as well as to define the time course of an evolving inflammatory response. Cytokine analysis was obtained prior to inoculation with M. intracellualre and on a weekly basis from day 0 to day 30 for all animals and again on day 60 for the animals sacrificed at day 60. All the animals had BAL performed prior to euthanasia at either 30- or 60-days post-inoculation. The animals were then taken directly to necropsy by a primate pathologist.
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Publication 2023
Adult Anesthesia Animals Autopsy Bronchoalveolar Lavage Bronchoscopes Bronchoscopy Callithrix Complete Blood Count Cytokine Euthanasia Inflammation Isoflurane Ketamine Mycobacterium Myeloid Progenitor Cells Nocardia Pathologists Phlebotomy Primates Serum Vaccination
Data and plasma from participants who were screened for the Phefumula cohort, a research bronchoscopy study described previously in Muema et al., 202015 and Khuzwayo et al., 2021,16 were used for this retrospective analysis. Adult males or females (self-reported gender) living with and without HIV, between 18 and 50 years, who were otherwise healthy (no chronic medical conditions, no current or past tobacco use, no current TB symptoms) were recruited from KwaDabeka Community Health Clinic in peri-urban KwaZulu-Natal, South Africa. The HIV status of all participants was determined by fourth generation enzyme linked-immunosorbent assay (ELISA) testing and HIV RNA plasma viral load (Sigma–Aldrich). Participants living with HIV were newly diagnosed and had not initiated antiretroviral therapy (ART) at the time of enrolment; on the day of enrolment they received immediate referral for ART-initiation according to South African guidelines. No longitudinal data was collected after ART initiation. BCG and influenza vaccination status were not recorded.
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Publication 2023
Adult Bronchoscopy Chronic Condition Enzyme-Linked Immunosorbent Assay Females Males Plasma Southern African People Therapeutics Vaccination Virus Vaccine, Influenza
All patients received PD-1/PD-L1 immune checkpoint inhibitors combined with platinum-based doublet chemotherapy as neoadjuvant chemoimmunotherapy. Chemoimmunotherapy drugs were given on the first day of each treatment cycle (21 days per cycle). A standard staging evaluation was performed before and after neoadjuvant chemoimmunotherapy, including a computed tomography (CT) scan (11 (link)); 18-F-fluorodeoxyglucose positron emission tomography/CT scan; magnetic resonance imaging or CT for the brain; and a bronchoscopy examination. All patients received 18-F-fluorodeoxyglucose positron emission tomography/CT scan to assess the presence of mediastinal involvement before and after neoadjuvant chemoimmunotherapy. Surgery was planned 3–7 weeks after the first day of the last treatment cycle. If there were progressive M1 or N3 metastasis after neoadjuvant chemoimmunotherapy, patients would continue medical therapy and be excluded from this study. The type of resection for the primary tumor was determined according to standard institutional procedures, including lobectomy, bronchial or vascular sleeve lobectomy, bilobectomy, and pneumonectomy. Systematic lymphadenectomy was performed in every patient. Decisions of conversion to thoracotomy were made by surgeons during operation whenever they felt necessary. Pathological responses and yield pathologic stage (yp-stage) were determined by the Department of Pathology according to resected samples.
Patients were divided into the VATS or RATS groups according to the initial surgery approach. Surgery approach was determined by patients’ will. All surgeries were performed by surgeons with extensive experience. VATS was performed in a two-port or three-port approach liberally. RATS was performed using the Da Vinci Xi surgery system (Intuitive Surgical, Inc., Mountain View, CA, USA), using the three-arm method. Patients without viable tumor cells in resected lymph nodes and primary lung cancer were defined as pCR, while less than 10% of viable tumor cells were defined as MPR, and more than 10% were defined as an incomplete pathological response (IPR) (12 (link)).
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Publication 2023
Antineoplastic Combined Chemotherapy Protocols Blood Vessel Brain Bronchi Bronchoscopy CD274 protein, human Cells F18, Fluorodeoxyglucose Feelings Immune Checkpoint Inhibitors Lung Cancer Lymph Node Excision Mediastinum Neoadjuvant Therapy Neoplasm Metastasis Neoplasms Operative Surgical Procedures Patients Pharmaceutical Preparations Platinum Pneumonectomy Radionuclide Imaging Rattus norvegicus Scan, CT PET Surgeons Therapeutics Thoracic Surgery, Video-Assisted Thoracotomy X-Ray Computed Tomography
A retrospective analysis of data about services provided to patients at Minia Cardiothoracic University Hospital was obtained from pre-pandemic era (2018–2019) and during the pandemic time (2020–2021). The two sets of data were compared together. Data were collected about the number of patients who underwent different procedures such as Pulmonary Function Tests, sleep studies or interventional chest procedures (bronchoscopy and thoracoscopy). Also, data were collected about the number of patients admitted in the chest ward, respiratory ICU and Coronary care unit (CCU) and number of patients who visited cardiothoracic, cardiology or chest outpatient clinics. Minia Cardiothoracic University Hospital has three departments: 1) chest department, with a capacity of 24 inward beds and 8 beds in respiratory intensive care unit, as well as pulmonary function unit, sleep study unit and interventional unit, which includes bronchoscopy and thoracoscopy, 2) cardiology department, with a capacity of 10 beds inward and 20 beds in CCU and 3) cardiothoracic surgery department, with a capacity 20 inward beds and 8 beds in post-operative care unit.
Publication 2023
Bronchoscopy Cardiovascular System Chest Lung Operative Surgical Procedures Pandemics Patients Polysomnography Postoperative Care Respiratory Rate Tests, Pulmonary Function Thoracoscopy

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More about "Bronchoscopy"

Bronchoscopy is a vital medical procedure that allows healthcare providers to closely examine the airways and lungs.
This minimally invasive technique involves the insertion of a flexible, lighted tube called a bronchoscope through the nose or mouth and into the respiratory system.
Bronchoscopy plays a crucial role in the diagnosis and treatment of various lung conditions, such as infections, cancer, and airway blockages.
During a bronchoscopy, the healthcare provider can obtain samples of lung tissue or fluid for further analysis, providing critical information to guide the management of respiratory disorders.
The procedure is generally well-tolerated, though patients may experience some temporary discomfort or a sore throat.
Proper preparation and anesthesia help ensure patient comfort and safety.
Bronchoscopes come in different models, including the BF-UC260F-OL8, BF-UC260F, BF-260, BF-1T260, and the NA-201SX-4022, each with its own unique features and capabilities.
Healthcare providers may also use related tools like the K-201 and EU-ME2 to support the bronchoscopy procedure.
Bronchoscopy is an essential tool in pulmonary medicine, allowing healthcare providers to see the airways and lungs in real-time and make informed decisions about the best course of treatment.
By understanding the nuances of this procedure and the various equipment involved, researchers and healthcare professionals can optimize their bronchoscopy studies and enhance the overall quality of patient care.