Patients were randomized to undergo EUS–FNA using either the standard or the fanning technique. At the time of the procedure, the endoscopy nurse opened an envelope containing computer-generated randomization assignments for the study patients. All procedures were performed by one endosonographer (S.V.) using a linear array echoendoscope (Olympus UCT140; Olympus, Tokyo, Japan). Procedures were performed under conscious sedation with patients in the left lateral decubitus position.
Pancreatic masses located in the head or uncinate process were sampled using a 25-G needle (Expect; Boston Scientific Corp., Natick, Massachusetts, USA) via the transduodenal route, and those in the pancreatic body or tail were sampled using a 22-G needle (Expect) via the transgastric route. The 25-G needles for transduodenal passes and 22-G needles for transgastric passes were based on the results of a previous study that demonstrated decreased needle dysfunction using this approach [13 ]. At FNA, suction was not applied in any of the cases, and after the first pass the stylet was not reintroduced into the needle assembly for subsequent FNAs.
Pancreatic masses located in the head or uncinate process were sampled using a 25-G needle (Expect; Boston Scientific Corp., Natick, Massachusetts, USA) via the transduodenal route, and those in the pancreatic body or tail were sampled using a 22-G needle (Expect) via the transgastric route. The 25-G needles for transduodenal passes and 22-G needles for transgastric passes were based on the results of a previous study that demonstrated decreased needle dysfunction using this approach [13 ]. At FNA, suction was not applied in any of the cases, and after the first pass the stylet was not reintroduced into the needle assembly for subsequent FNAs.