The study was approved by Institutional Review Board at Vanderbilt University Medical Center and involved two phases; Phase 1-derivation phase, followed by Phase 2-validation phase. In Phase 1, matched measurements of oxygen saturation by pulse oximetry (SpO2) and partial pressure of oxygen in arterial blood (PaO2) were obtained from 2 groups of patients: Group 1: those undergoing general anesthesia at Vanderbilt University Medical Center from 2002 to 2007 and Group 2: patients from the ARDS network -low versus high tidal volume for the Acute Respiratory Management of ARDS (ARMA) database.(8 (link)) We limited data points to those with SpO2 ≤ 98% to maximize matched data in the linear range of the sigmoidal association between SpO2 and PaO2 in the oxyhemoglobin curve, and at the same time maintain clinical relevance and adequate sample size, given that it is unlikely that patients with higher SpO2 would have PF ratios of less than 400 and thus impact the SOFA score. SF ratios corresponding to PF ratios of 100, 200, 300 and 400 were then derived. In Phase 2, the SOFA scores calculated by using these SF ratios were validated against outcomes in a 3rd group of surgical and trauma ICU patients.
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Oximetry, Pulse
Oximetry, Pulse
Oximetry and Pulse are important clinical measurements that provide insights into cardiovascular and respiratory function.
Oximetry involves the non-invasive assessment of oxygen saturation in the blood, while Pulse measurements track the rhythmic expansion and contraction of arteries.
These parameters offer valuable data for diagnosing and monitoring a wide range of medical conditions, from heart disease to sleep disorders.
Researchers and clinicians rely on carefully designed protocols to accurately capture and interpret Oximetry and Pulse data, requiring a thorough understanding of the latest evidence-based approaches.
PubComapre.ai's innovative AI-driven comparison tool helps streamline this process, enabling users to quickly identify the most effective Oximetry and Pulse research protocols from the literature, preprints, and patents.
By leveraging this powerful resource, researchers can optimize their data collection and analysis, staying ahead of the curve in this critical area of medical research.
Oximetry involves the non-invasive assessment of oxygen saturation in the blood, while Pulse measurements track the rhythmic expansion and contraction of arteries.
These parameters offer valuable data for diagnosing and monitoring a wide range of medical conditions, from heart disease to sleep disorders.
Researchers and clinicians rely on carefully designed protocols to accurately capture and interpret Oximetry and Pulse data, requiring a thorough understanding of the latest evidence-based approaches.
PubComapre.ai's innovative AI-driven comparison tool helps streamline this process, enabling users to quickly identify the most effective Oximetry and Pulse research protocols from the literature, preprints, and patents.
By leveraging this powerful resource, researchers can optimize their data collection and analysis, staying ahead of the curve in this critical area of medical research.
Most cited protocols related to «Oximetry, Pulse»
Anesthesia
Arteries
Ethics Committees, Research
Lung Volume Measurements
Operative Surgical Procedures
Oximetry
Oximetry, Pulse
Oxygen
Oxyhemoglobin
Partial Pressure
Patients
Respiratory Distress Syndrome, Acute
Saturation of Peripheral Oxygen
Wounds and Injuries
Enrollment for ACTT-1 began on February 21, 2020, and ended on April 19, 2020. There were 60 trial sites and 13 subsites in the United States (45 sites), Denmark (8), the United Kingdom (5), Greece (4), Germany (3), Korea (2), Mexico (2), Spain (2), Japan (1), and Singapore (1). Eligible patients were randomly assigned in a 1:1 ratio to receive either remdesivir or placebo. Randomization was stratified by study site and disease severity at enrollment. Patients were considered to have severe disease if they required mechanical ventilation, if they required supplemental oxygen, if the oxygen saturation as measured by pulse oximetry (Spo 2) was 94% or lower while they were breathing ambient air, or if they had tachypnea (respiratory rate ≥24 breaths per minute). Remdesivir was administered intravenously as a 200-mg loading dose on day 1, followed by a 100-mg maintenance dose administered daily on days 2 through 10 or until hospital discharge or death. A matching placebo was administered according to the same schedule and in the same volume as the active drug. A normal saline placebo was used at the European sites and at some non-European sites owing to a shortage of matching placebo; for these sites, the remdesivir and placebo infusions were masked with an opaque bag and tubing covers to maintain blinding. All patients received supportive care according to the standard of care for the trial site hospital. If a hospital had a written policy or guideline for use of other treatments for Covid-19, patients could receive those treatments. In the absence of a written policy or guideline, other experimental treatment or off-label use of marketed medications intended as specific treatment for Covid-19 were prohibited from day 1 through day 29 (though such medications could have been used before enrollment in this trial).
The trial protocol was approved by the institutional review board at each site (or by a centralized institutional review board as applicable) and was overseen by an independent data and safety monitoring board. Written informed consent (or consent by other institutional review board-approved process) was obtained from each patient or from the patient’s legally authorized representative if the patient was unable to provide consent. Full details of the trial design, conduct, oversight, and analyses can be found in theprotocol and statistical analysis plan (available with the full text of this article at NEJM.org).
The trial protocol was approved by the institutional review board at each site (or by a centralized institutional review board as applicable) and was overseen by an independent data and safety monitoring board. Written informed consent (or consent by other institutional review board-approved process) was obtained from each patient or from the patient’s legally authorized representative if the patient was unable to provide consent. Full details of the trial design, conduct, oversight, and analyses can be found in the
Clinical Trials Data Monitoring Committees
COVID 19
Drug Labeling
Ethics Committees, Research
Europeans
Mechanical Ventilation
Normal Saline
Oximetry, Pulse
Oxygen
Oxygen Saturation
Patient Discharge
Patient Representatives
Patients
Pharmaceutical Preparations
Placebos
remdesivir
Respiratory Rate
Saturation of Peripheral Oxygen
Therapies, Investigational
Aged
Cellulitis
Clostridium difficile
Diagnosis
Diarrhea
Fever
Gastroenteritis
Infections, Hospital
Influenza
Leukocyte Count
Long-Term Care
Norovirus
Oximetry, Pulse
Pneumonia
Pressure Ulcer
Respiratory Tract Infections
Scabies
Soft Tissue Infection
Technology Assessment, Biomedical
Urinalysis
Urinary Tract Infection
Urine
Birth
Condoms
Continuous Positive Airway Pressure
Genital Infantilism
Gestational Age
Infant
Multiple Birth Offspring
Neoplasm Metastasis
Obstetric Delivery
Oximetry, Pulse
Oxygen
Oxygen Saturation
Patients
Precipitating Factors
Preterm Infant
Pulse Rate
Surfactants
The outcome of interest was in-hospital mortality among children hospitalized with LRTI. As potential predictors of mortality, we considered the following classes of variables: Demographics, medical history, history of present illness, signs on physical exam, growth standards, chest radiography, and C-reactive protein levels. Information on these variables was collected by study physicians on a standardized case report form when a child was hospitalized. Subjective information on symptoms occurring prior to hospitalization was obtained from the child's caregiver at the time of hospitalization.
For this analysis, age was categorized based on IMCI categories: 6 weeks–2 months, 3–12 months, and 12–23 months. Children were considered to have low oxygen saturation if a pulse oximetry reading on room air was ≤90%. Three growth standards were also evaluated: weight for age, weight for length, and length for age, categorized based on the WHO z-scores [13] . Tables of growth standards were accessed at:http://www.who.int/childgrowth/standards/ . Chest radiographs were evaluated independently by a pediatrician and a radiologist. C-reactive protein levels were categorized as >40 mg/L or ≤40 mg/L, which may indicate bacterial pneumonia [14] (link). For children with HIV infection, the clinical classification of HIV disease without CD4 count was recorded using the CDC categories – N (asymptomatic), A (mildly symptomatic), B (moderately symptomatic), C (severely symptomatic, AIDS-defining) [15] .
For this analysis, age was categorized based on IMCI categories: 6 weeks–2 months, 3–12 months, and 12–23 months. Children were considered to have low oxygen saturation if a pulse oximetry reading on room air was ≤90%. Three growth standards were also evaluated: weight for age, weight for length, and length for age, categorized based on the WHO z-scores [13] . Tables of growth standards were accessed at:
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Acquired Immunodeficiency Syndrome
CD4+ Cell Counts
Child
C Reactive Protein
HIV Infections
Hospitalization
Oximetry, Pulse
Oxygen Saturation
Pediatricians
Physical Examination
Physicians
Pneumonia, Bacterial
Radiography, Thoracic
Radiologist
Most recents protocols related to «Oximetry, Pulse»
This was a prospective, randomized, simulation study that was conducted over 4 months, from November 2019 to February 2020, among second- to fourth-year paramedic students who had clinical practice at the Emergency Medical Center of a university-affiliated hospital. Those who voluntarily agreed to participate were included in the study. Participants were divided into 2 groups: men and women. In each group, the participants performed chest compressions on the Resusci Anne QCPR/SimPad PLUS with SkillReporter (Laerdal, Stavanger, Norway) in pairs. The total chest compression time was defined as 20 minutes assuming an in-hospital cardiac arrest scenario. In the 2-minute scenario, each participant was positioned opposite the other and performed chest compressions for 2 minutes, then took a 10-second break pretending to check the pulse and rhythm. Immediately after each chest compression, investigators measured heart rate using pulse oximetry and the degree of fatigue using questionnaires. This was repeated 5 times in 20 minutes. In the 1-minute scenario, each participant performed chest compressions for 1 minute and took a 10-second break every 2 minutes. This process was repeated 10 times in 20 minutes. After a 3-hour break, under the assumption of full recovery from fatigue, the participants in the 1-minute group crossed over to the 2-minute group and vice versa. In addition, to compare the quality of chest compressions over time, 1 set was performed for 4 minutes and 5 sets were performed in 20 minutes to compare parameters between the 2 groups. This was defined based on a minimum of 4 minutes taken for performing chest compressions by both sets of participants in the 2-minute group. All participants provided informed consent. The Institutional Review Board of the hospital reviewed and approved the specific procedures (CR-19-144).
Cardiac Arrest
Chest
Crossing Over, Genetic
Emergencies
Ethics Committees, Research
Fatigue
Oximetry, Pulse
Paramedical Personnel
Pulse Rate
Rate, Heart
Student
Woman
The patients received their usual cardiac medications in the early morning on the day of surgery. Upon arriving OR, the patients were premedicated with midazolam 0.02 mg/kg and fentanyl 1 mcg/kg. A five-lead EKG, pulse oximetry, and noninvasive blood pressure monitoring were initiated. Then, we inserted a catheter into the radial artery under local anesthesia for invasive blood pressure monitoring. General anesthesia induction consisted of fentanyl 5–10 mcg/kg, midazolam 0.2–0.4 mg/kg, and pancuronium 0.1–0.15 mg/kg. Additionally, propofol 0.5–1 mg/kg was administered as appropriate. After intubation, we inserted a right internal jugular multilumen central venous catheter. Maintenance of anesthesia was with sevoflurane 1%–2%, adjusted by clinical conditions and pancuronium as needed.
Anesthesia
Arteries, Radial
Blood Pressure
Catheters
Fentanyl
General Anesthesia
Heart
Intubation
Local Anesthesia
Midazolam
Oximetry, Pulse
Pancuronium
Patients
Pharmaceutical Preparations
Propofol
Sevoflurane
Surgery, Day
Training Programs
Venous Catheter, Central
All procedures were finished under general anesthesia following a standardized clinical routine. Routine monitoring of electrocardiogram, blood pressure, and pulse oximetry were carried out. General anesthesia was induced with propofol, remifentanil, and rocuronium, and the dosage of drugs depended on the body weight of the patient. The maintenance of anesthesia was implemented by the use of remifentanil and propofol, oxygen, and air (26 (link)). In accordance with the PONV prevention guidelines, we routinely provided dexamethasone and palonosetron at the end of surgery (13 (link), 27 (link)).
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Anesthesia
Blood Pressure
Body Weight
Dexamethasone
Electrocardiogram
General Anesthesia
Operative Surgical Procedures
Oximetry, Pulse
Oxygen
Palonosetron
Patients
Pharmaceutical Preparations
Postoperative Nausea and Vomiting
Propofol
Remifentanil
Rocuronium
The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). This was a retrospective study registered as a service review and approved by the institutional review board of Guy’s and St Thomas’ NHS Foundation Trust (Approval No. LIRB: 2021/12240) and individual consent for this retrospective analysis was waived. Data were collected from the electronic patient records of all patients referred to the Lane Fox Unit (Respiratory High Dependency Unit, St Thomas’ Hospital, London, UK) and to the Sleep Disorders Centre (Guy’s Hospital, London, UK) for pre-operative screening of SDB prior to bariatric surgery (June 2014 to February 2021). The strategy employed in the pre-operative screening process has been outlined elsewhere (3 (link)). Patients referred for bariatric surgery completed a STOP-BANG questionnaire and those who scored >4 points were referred for a nocturnal pulse oximetry for two consecutive nights (3 (link)). Data collected included demographic data, sleep study data, co-morbidities, post-operative complications, maximal level of respiratory support, LOS, mortality, and the highest level of care (Appendix 1 ). Respiratory support data were included only if there was available documentation for the daily oxygen requirements during the whole inpatient stay. Complications are presented according to the Clavien-Dindo classification of post-operative complications. The follow up period was until discharge from hospital and these data were obtained from the electronic patient records.
All sleep data were analysed and reviewed by a sleep technician and a physician with a specialist interest in sleep who recommended the appropriate treatment. OSA was classified based on the 4% oxygen desaturation index (ODI); it was mild with an ODI of 5.0–14.9 events/hour, moderate with an ODI of 15.0–29.9 events/hour, and an ODI of 30 events/hour and above classified as severe OSA. Patients were generally offered CPAP therapy if they had moderate or severe OSA, or mild OSA with significant associated symptoms. Patients with no OSA, or mild OSA without significant symptoms were not offered CPAP therapy. The CPAP device offered was a ResMed AirSense 10 Autoset (ResMed, San Diego, California, USA) and the non-invasive ventilation (NIV) device offered was a ResMed Lumis 150 VPAP ST-A (ResMed, San Diego, California, USA).
All sleep data were analysed and reviewed by a sleep technician and a physician with a specialist interest in sleep who recommended the appropriate treatment. OSA was classified based on the 4% oxygen desaturation index (ODI); it was mild with an ODI of 5.0–14.9 events/hour, moderate with an ODI of 15.0–29.9 events/hour, and an ODI of 30 events/hour and above classified as severe OSA. Patients were generally offered CPAP therapy if they had moderate or severe OSA, or mild OSA with significant associated symptoms. Patients with no OSA, or mild OSA without significant symptoms were not offered CPAP therapy. The CPAP device offered was a ResMed AirSense 10 Autoset (ResMed, San Diego, California, USA) and the non-invasive ventilation (NIV) device offered was a ResMed Lumis 150 VPAP ST-A (ResMed, San Diego, California, USA).
Bariatric Surgery
Continuous Positive Airway Pressure
Ethics Committees, Research
Inpatient
Medical Devices
Noninvasive Ventilation
Oximetry, Pulse
Oxygen
Oxygen-14
Oxygen-15
Patient Discharge
Patients
Physicians
Polysomnography
Postoperative Complications
Respiratory Rate
Sleep
Sleep Disorders
Therapeutics
We conducted a retrospective review of real-world data from routine care of all the patients admitted in a Level I trauma center (Centre Hospitalo-Universitaire des Hospices Civiles de Lyon, France) with severe thoracic trauma who underwent SSRF from September 2010 to January 2020. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). The study received Institutional Review Board approval from the French Society of Thoracic and Cardio-Vascular Surgery (Société Française de Chirurgie Thoracique et Cardio-Vasculaire – IRB00012919 – 05/04/2022) and informed consent was taken from all the patients.
Severe thoracic trauma was defined by an Abbreviated Injury Scale (AIS) of 3 or more (16 (link)). All selected patients had 3 or more displaced rib fractures or flail chest [as defined per the taxonomy of Edwards et al. (17 (link))], a respiratory rate >25 cycles/min or hypoxemia on pulse oximetry (<90% without oxygen) or a circulatory failure (systolic arterial pressure <110 mmHg, or more than 30% decrease in systolic arterial pressure). On admission, full body CT scan (Figure 1 ) screened all patients with severe thoracic trauma without severe hemodynamic instability or life-threatening injury. Patients were managed according to the guidelines of the French society of critical care and anesthesia (18 (link)). All life threatening or hemorrhagic lesions were treated before SSRF.
Severe thoracic trauma was defined by an Abbreviated Injury Scale (AIS) of 3 or more (16 (link)). All selected patients had 3 or more displaced rib fractures or flail chest [as defined per the taxonomy of Edwards et al. (17 (link))], a respiratory rate >25 cycles/min or hypoxemia on pulse oximetry (<90% without oxygen) or a circulatory failure (systolic arterial pressure <110 mmHg, or more than 30% decrease in systolic arterial pressure). On admission, full body CT scan (
Anesthesia
Critical Care
Ethics Committees, Research
Flail Chest
Hemodynamics
Hemorrhage
Hospice Care
Human Body
Injuries
Oximetry, Pulse
Oxygen
Patients
Respiratory Rate
Rib Fractures
Shock
Systolic Pressure
Thoracic Injuries
Vascular Surgical Procedures
X-Ray Computed Tomography
Top products related to «Oximetry, Pulse»
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The MiniMuffs are a compact and portable noise-reduction system designed for use in medical and laboratory settings. The product's core function is to provide a controlled acoustic environment to protect sensitive hearing during procedures or examinations.
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The MouseOx Plus is a non-invasive monitoring system designed for use with small laboratory animals, such as mice. It is capable of measuring various physiological parameters, including heart rate, breathing rate, oxygen saturation, and body temperature.
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MouseOx is a non-invasive monitoring system designed for small animals. It measures key physiological parameters such as heart rate, breathing rate, oxygen saturation, and body temperature. The device provides real-time data through a sensor that is placed on the animal's body.
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Alice 5 is a comprehensive sleep diagnostic device designed for the assessment of sleep disorders. It provides comprehensive data collection and analysis capabilities to support the diagnosis and management of sleep-related conditions.
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The Radical-7 is a versatile patient monitoring system designed for use in healthcare settings. It provides continuous, noninvasive measurement of oxygen saturation, pulse rate, and other vital signs. The Radical-7 utilizes Masimo's trusted signal processing technology to deliver accurate and reliable data, enabling healthcare professionals to make informed decisions about patient care.
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The ApneaLink is a compact and portable diagnostic device designed for the screening and detection of sleep apnea. It records respiratory signals and oxygen levels during sleep, providing healthcare professionals with the necessary data to assess the presence and severity of sleep-disordered breathing.
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The Alice 6 is a lab equipment product designed for sleep analysis. It is a diagnostic device that records various physiological signals during sleep to help healthcare professionals assess sleep patterns and disorders.
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MATLAB is a high-performance programming language and numerical computing environment used for scientific and engineering calculations, data analysis, and visualization. It provides a comprehensive set of tools for solving complex mathematical and computational problems.
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Isoflurane is a volatile anesthetic agent used in the medical field. It is a clear, colorless, and nonflammable liquid that is vaporized and administered through inhalation. Isoflurane is primarily used to induce and maintain general anesthesia during surgical procedures.
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The ApneaLink Plus is a portable sleep apnea screening device. It measures airflow, respiratory effort, and blood oxygen levels to detect the presence of sleep-disordered breathing.
More about "Oximetry, Pulse"
Oximetry and Pulse Monitoring: Unlocking Insights into Cardiovascular and Respiratory Health Oximetry and pulse measurements are vital clinical tools that provide invaluable data for diagnosing and monitoring a wide range of medical conditions.
Oximetry, the non-invasive assessment of oxygen saturation in the blood, offers insights into cardiovascular and respiratory function.
Pulse measurements, which track the rhythmic expansion and contraction of arteries, further enhance our understanding of these critical physiological processes.
Researchers and clinicians utilize carefully designed protocols to accurately capture and interpret Oximetry and Pulse data, requiring a thorough understanding of the latest evidence-based approaches.
From MiniMuffs and MouseOx Plus devices to the Alice 5 and 6 sleep study systems, a range of specialized tools are available to support this important work.
PubCompare.ai's innovative AI-driven comparison tool helps streamline the research process, enabling users to quickly identify the most effective Oximetry and Pulse research protocols from the literature, preprints, and patents.
By leveraging this powerful resource, researchers can optimize their data collection and analysis, staying ahead of the curve in this critical area of medical research.
Whether you're exploring the use of Isoflurane in animal studies or utilizing MATLAB to analyze ApneaLink Plus data, PubCompare.ai's solutions can help you navigate the complexities of Oximetry and Pulse research.
Experience the difference today and unlock the full potential of these essential clinical measurements.
Oximetry, the non-invasive assessment of oxygen saturation in the blood, offers insights into cardiovascular and respiratory function.
Pulse measurements, which track the rhythmic expansion and contraction of arteries, further enhance our understanding of these critical physiological processes.
Researchers and clinicians utilize carefully designed protocols to accurately capture and interpret Oximetry and Pulse data, requiring a thorough understanding of the latest evidence-based approaches.
From MiniMuffs and MouseOx Plus devices to the Alice 5 and 6 sleep study systems, a range of specialized tools are available to support this important work.
PubCompare.ai's innovative AI-driven comparison tool helps streamline the research process, enabling users to quickly identify the most effective Oximetry and Pulse research protocols from the literature, preprints, and patents.
By leveraging this powerful resource, researchers can optimize their data collection and analysis, staying ahead of the curve in this critical area of medical research.
Whether you're exploring the use of Isoflurane in animal studies or utilizing MATLAB to analyze ApneaLink Plus data, PubCompare.ai's solutions can help you navigate the complexities of Oximetry and Pulse research.
Experience the difference today and unlock the full potential of these essential clinical measurements.