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Pressures, Maximum Inspiratory

Pressures, Maximum Inspiratory: The maximum force or tension generated by the inspiratory muscles during inhalation.
This measure provides information about the strength and function of the respiratory musculature and can be used to assess respiratory disorders, such as airflow limitation or neuromusclar diseases.
Accurate measurement of maximum inspiratory pressures is important for diagnosis, monitoring, and treatment of respiratory conditions.

Most cited protocols related to «Pressures, Maximum Inspiratory»

1
Manometric Assessment of Esophagogastric Junction
Manometric studies were performed in the supine position after at least a 6-h fast. The HRM catheters were 4.2 mm outer diameter solid-state assemblies with 36 circumferential sensors at 1-cm intervals (Given Imaging, Duluth, GA, USA). Transducers were calibrated at 0 and 300 mmHg using externally applied pressure. Manometric assemblies were placed transnasally and positioned to record from the hypopharynx to the stomach with at least three intragastric sensors. The manometric protocol included a 5-min baseline recording and ten 5-mL swallows in the supine position.
Manometric studies were analyzed with Manoview analysis software (Given Imaging, Duluth, GA, USA). The EPT metrics utilized for the Chicago Classification [3 (link),4 (link)] were the integrative relaxation pressure (IRP), distal contractile integrity (DCI), contractile front velocity (CFV) and distal latency (DL) [5 (link)]. Metrics utilized to quantify resting EGJ pressure (HRM EGJ metrics) were the following:

Lower esophageal sphincter pressure integral (LES-PI) as described by Hoshino [4 (link)] determined by enclosing the domain of the LES area during a 10s-period time with the DCI tool, setting the threshold isobaric contour (IBC) at 20 mmHg

A novel metric, EGJ contractile index (EGJ-CI) developed as an alternative to the LES-PI (Figure 1). As with the LES-PI, the upper and lower margins of the EGJ were enclosed in a DCI tool box. However, the duration of the box was exactly three consecutive respiratory cycles and the threshold IBC was set at 2 mmHg above the gastric pressure. The value computed with the DCI tool in mmHg-s-cm was then divided by the duration of the three respiratory cycles (in seconds) yielding EGJ-CI units of mmHg-cm. Hence, although time is not a factor in EGJ-CI units, the measure does reflect the contractility of the EGJ for a period of three respiratory cycles.

Inspiratory EGJ pressure (EGJP-insp). Average maximal inspiratory EGJ pressure for 3 respiratory cycles, ideally in a quiescent portion of recording, free of swallows

Expiratory EGJ pressure (EGJP-exp). Average EGJ pressure midway between inspirations for the same 3 respiratory cycles

Separation between the LES and crural diaphragm (LES-CD). The EGJ pressure profile on a spatial pressure variation plot at peak inspiration can be a single or double peak. If a single peak, the LES-CD separation is 0; if a double peak, LES-CD separation is the axial distance between peaks.

Nicodème F., Pipa-Muniz M., Khanna K., Kahrilas P.J, & Pandolfino J.E. (2013). Quantifying esophagogastric junction contractility with a novel HRM topographic metric, the EGJ-Contractile Integral: normative values and preliminary evaluation in PPI non-responders. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(3), 353-360.
Publication 2013
A-factor (Streptomyces) Catheters Hypopharynx Inhalation Leg Manometry Maximal Respiratory Pressures MM 36 Muscle Contraction Neoplasm Metastasis Pressure Pressures, Maximum Inspiratory Respiratory Rate Stomach Swallows Transducers Vaginal Diaphragm
2
Diaphragm Ultrasound for Weaning Prediction
When the abovementioned criteria were reached, patients were disconnected from the tube and a spontaneous breathing trial was attempted for 1 h administering supplemental oxygen to achieve a peripheral oxygen saturation (SpO2) >94%. Then, each diaphragm was evaluated by B-mode and M-mode ultrasound subcostal views to rule out abnormalities in muscle movement [13 (link)]. When dysfunction of a single hemi-diaphragm was detected, patients were excluded from the study. Hereafter, right hemi-diaphragm ultrasound scans were performed with patients lying down at a semi-recumbent position (45°). Rapid shallow breathing index and maximum inspiratory pressure (PImax) were also recorded. Weaning failure was defined as the inability to maintain spontaneous breathing for at least 48 h, without any ventilatory support. Criteria for failure to the spontaneous breathing trial were the following: change in mental status, onset of discomfort, diaphoresis, respiratory rate (RR) >35 breaths/min, hemodynamic instability (heart rate >140, systolic blood pressure >180 or <90 mmHg), or signs of increased work of breathing [14 (link)]. Clinicians in charge of the patient's care were blinded to ultrasound measurements.
Ferrari G., De Filippi G., Elia F., Panero F., Volpicelli G, & Aprà F. (2014). Diaphragm ultrasound as a new index of discontinuation from mechanical ventilation. Critical Ultrasound Journal, 6(1), 8.
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Publication 2014
Hemodynamics Mental Disorders Movement Disorders Muscle Tissue Oxygen Patients Pressures, Maximum Inspiratory Rate, Heart Respiratory Rate Saturation of Peripheral Oxygen Systolic Pressure Ultrasonography
3
Respiratory Muscle Strength Measurement Protocol
The respiratory muscle strength, maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP) were measured using a pressure gauge (Respiratory Pressure Meter, Micro Medical Corp, England). MIP and MEP were measured five times, and the highest value was used as the final value.15 (link) For the MIP, patients were asked to exhale to the residual volume and then perform a rapid maximal inspiratory effort, sustained for 1–2 seconds. For MEP, patients were asked to inspire to the total lung capacity and then perform a rapid and maximal expiratory effort, sustained for 1–2 seconds.
Yang S.H., Yang M.C., Wu Y.K., Wu C.W., Hsieh P.C., Kuo C.Y., Tzeng I.S, & Lan C.C. (2021). Poor Work Efficiency is Associated with Poor Exercise Capacity and Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease, 16, 245-256.
Publication 2021
Exhaling Inhalation Muscle Strength Neoplasm Metastasis Patients Pressure Pressures, Maximum Expiratory Pressures, Maximum Inspiratory Respiratory Muscles Respiratory Rate Volume, Residual
4
Evaluating Prognostic Factors in Palliative Care
We summarized the baseline demographics using descriptive statistics, including means, medians, proportions, standard deviations (SD), interquartile ranges (IQR), and 95% confidence intervals (95% CI).
We used both unadjusted and standardized phase angle (SPA) for analysis, where SPA = (phase angle − age/sex/body mass index specific mean phase angle value)/standard deviation of the age/sex/body mass index specific standard deviation of the healthy population.31 We used the Kaplan Meir method for survival analysis, and log rank tests to compare between groups.
We conducted multivariate Cox Proportional Hazards regression analysis with backward selection incorporating variables with P-value <0.10 in univariate survival analysis. These variables included the PaP score, PPI, serum albumin, fat free mass, unadjusted phase angle, hand grip strength, maximal inspiratory pressure and standardized phase angle. Age and sex were also included because hand grip strength and maximal inspiratory pressure are dependent on these variables. Palliative Performance status and Karnofsky Performance Status were not included in the multivariate model because they were already part of PaP and PPI, and correlated strongly with these prognostic scores.
We also determined the association between phase angle (both unadjusted and standardized) with various prognostic variables using the Spearman Correlation test.
The sample size justification was based on having at least 10 events (i.e. deaths) for each prognostic variable in the multivariable Cox Proportional Hazards regression model. We anticipated observing at least 120 deaths in 200 patients, thereby providing enough information to include up to 12 prognostic variables in the model. In total, we recruited 222 patients to ensure at least 200 patients completed all 3 functional measures.
The Statistical Analysis System (SAS version 9.2, SAS Institute, Cary, North Carolina) were used for statistical analysis. A P-value of <0.05 was considered significant.
Hui D., Bansal S., Morgado M., Dev R., Chisholm G, & Bruera E. (2014). Phase Angle for Prognostication of Survival in Patients with Advanced Cancer: Preliminary Findings. Cancer, 120(14), 2207-2214.
Publication 2014
Index, Body Mass Patients Pressures, Maximum Inspiratory Serum Albumin
5
Inspiratory Resistance Training Protocols
This circuit design provides a platform from which a number of inspiratory resistance protocols are compatible and possible. One of the simpler methodologies would be to employ an on/off binary protocol, where the maximal resistance on the POWERbreathe is set to a percentage of each participant’s maximum inspiratory pressure (which can be tested using a standardized maximal inspiratory pressure protocol on the POWERbreathe device). To demonstrate this, we conducted physiological recordings during repeated applications of an inspiratory resistance value of 55 cmH2O, which was determined by calculating 70% of the participant’s maximal inspiratory pressure of 79 cmH2O. The participant was instructed to maintain normal breathing depth and rate during the resistive loading periods.
Alternatively, graded levels of inspiratory resistance could be employed via a pre-determined protocol input to the POWERbreathe, although visual feedback may be a necessity here to ensure participants reach the desired inspiratory pressure in each trial. To demonstrate this protocol, we repeatedly activated valve 1 with 5 cmH2O graded increases in set pressure from 5 to 30 cmH2O.
Rieger S.W., Stephan K.E, & Harrison O.K. (2020). Remote, Automated, and MRI-Compatible Administration of Interoceptive Inspiratory Resistive Loading. Frontiers in Human Neuroscience, 14, 161.
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Publication 2020
Inhalation Medical Devices physiology Pressure Pressures, Maximum Inspiratory Visual Feedback

Most recents protocols related to «Pressures, Maximum Inspiratory»

1
Measuring Respiratory Muscle Strength
An analog manovacuometer with a range of ±300 cmH2O (Murenas, Juiz de Fora, Minas Gerais, Brazil) was used to measure maximal respiratory pressures as quantitative changes in respiratory muscle strength (Black and Hyatt, 1969 (link); Silva Andrade et al., 2022 (link)). Expiratory pressure was calculated from the total lung capacity, represented by the maximum expiratory pressure (MEP), and the maximum inspiratory pressure (MIP) was measured at the residual volume level. The participant was positioned in a comfortable chair in Fowler’s position, with the upper limbs beside the body and the lower limbs flexed at a 90° angle. The mouthpiece of the device was adapted to the participant’s oral cavity with the nose occluded using a nose clip. Verbal commands were delivered by a single trained evaluator, instructing the participant to fully exhale, try to empty the lungs as much as possible, and then inhale deeply and quickly through the mouth. MIP was measured from the residual volume. The mouthpiece of the device was again attached to the participant’s mouth with the nose occluded using a nose clip, and the participant was instructed to inhale completely, trying to fill the lungs as much as possible. The command was then delivered to exhale deeply and quickly through the mouth. MEP was measured using total lung capacity. The procedures were performed thrice, with a measurement interval from one pressure to another of 1 min, considering the highest pressure valid.
Fabrin S.C., Palinkas M., Fioco E.M., Gomes G.G., Regueiro E.M., da Silva G.P., Siéssere S., Verri E.D, & Regalo S.C. (2023). Functional assessment of respiratory muscles and lung capacity of CrossFit athletes. Journal of Exercise Rehabilitation, 19(1), 67-74.
Publication 2023
Clip Exhaling Human Body Inhalation Lower Extremity Lung Maximal Respiratory Pressures Medical Devices Muscle Strength Nose Oral Cavity Pressure Pressures, Maximum Expiratory Pressures, Maximum Inspiratory Respiratory Muscles Respiratory Rate Upper Extremity Volume, Residual
2
Bilevel PAP for Obstructive Sleep Apnea
All patients were switched from CPAP/APAP to bilevel PAP with an AirCurve 10 VAuto device (ResMed SAS, Saint-Priest, France) (Figure 1). Physicians set the minimum expiratory positive airway pressure (EPAP; not below 4 cmH2O) and maximum inspiratory positive airway pressure (IPAP) based on average values during previous CPAP/APAP, then the device automatically adjusts values within these two limits. The goal was for bilevel PAP to effectively treat obstructive events (apneas and hypopneas). Patients were given oral and written instructions on how to use the device before returning home, and had access to a helpline in case of any problems.
Palot A., Nguyên X.L., Launois S., Prigent A., Graml A., Aversenq E., Koltes C., Recart D, & Lavergne F. (2023). Effect of switching from continuous to bilevel positive airway pressure on sleep quality in patients with obstructive sleep apnea: the prospective POP IN VAuto study. Journal of Thoracic Disease, 15(2), 918-927.
Publication 2023
Acetaminophen Apnea Continuous Positive Airway Pressure Exhaling Medical Devices Patients Physicians Pressure Pressures, Maximum Inspiratory
3
Perioperative Respiratory Function Assessment
After being allotted into groups, the patients in the two groups were visited one day before the surgery. Demographic data such as age, height, weight, body mass index (BMI), sex, smoking history, and type of surgery were collected.
Six-minute walk test (6MWT): The patients performed a 6MWT according to the American Society’s guidelines during the preoperative period.17 (link) Dyspnoea and fatigue, mean arterial pressure (MAP), heart rate (HR), and oxygen saturation (SpO2) were measured at the start and immediately after finishing the test. A modified Borg scale was used to measure dyspnoea and fatigue. Distance covered in meters after 6 minutes was the main outcome of the test.
All the subjects underwent evaluations of hemodynamic indexes including MAP, HR, and SpO2 were also recorded on the 1st, 3rd, and 5th postoperative days for both groups. The primary outcome measurements were changes to pulmonary function through the following parameters: maximal inspiratory pressure (MIP), peak expiratory flow (PEF), vital capacity max (Vcmax), FEV1, FVC, and FEV1/FVC. In addition, blood gas indexes such as bass excess (BE), partial pressure of arterial oxygen (PaO2), partial pressure of arterial carbon dioxide (PaCO2), and pH values were recorded. These measurements were taken in the preoperative period and were repeated on the 1st, 3rd, and 5th postoperative days for both groups.
Zhao C.H., Sun Y.H, & Mao X.M. (2023). Volume Incentive Spirometry Reduces Pulmonary Complications in Patients After Open Abdominal Surgery: A Randomized Clinical Trial. International Journal of General Medicine, 16, 793-801.
Publication 2023
6-Minute Walk Test Arteries Bass BLOOD Carbon dioxide Dyspnea Exhaling Fatigue Hemodynamics Index, Body Mass Lung Operative Surgical Procedures Oxygen Oxygen Saturation Partial Pressure Patients Pressures, Maximum Inspiratory Rate, Heart Saturation of Peripheral Oxygen Surgery, Day Vital Capacity
4
Retrospective Study of NIV Initiation in ALS
This was a retrospective monocentric study. Data were collected between September 2017 and June 2021 from all patients followed in the Bordeaux ALS Centre and for whom NIV initiation was decided.
The indication for NIV was given by the neurologist according to guideline recommendations [12 (link)] and was based on the presence of symptoms of respiratory muscle weakness (at least one of the following: dyspnoea, tachypnoea, orthopnoea, disturbed sleep due to nocturnal desaturation/arousals, morning headache, use of auxiliary respiratory muscles at rest, paradoxical respiration, daytime fatigue, excessive daytime sleepiness (ESS >9) and abnormal respiratory function tests (with at least one of the following elements: vital capacity <80%, nocturnal peripheral oxygen saturation (SpO2) <90%, time >5% (French recommendations [3 (link)])), sudden nasal inspiratory pressure (SNIP) <40 cmH2O, maximum inspiratory pressure (MIP) <60cmH2O) or hypercapnia.
Some patients refused to try NIV. For the others, home NIV initiation was then proposed, except in those with an arterial carbon dioxide tension (PaCO2) above 6.1 kPa, those without a caregiver and those who were already hospitalised and for whom NIV was initiated in the hospital.
NIV prescription corresponded to the day of the NIV initiation request by the Bordeaux ALS Centre.
The duration of chart inclusion was from the first day of NIV initiation to the 30th day of the last patient included.
Réginault T., Bouteleux B., Wibart P., Mathis S., Le Masson G., Pillet O, & Grassion L. (2023). At-home noninvasive ventilation initiation with telemonitoring in amyotrophic lateral sclerosis patients: a retrospective study. ERJ Open Research, 9(1), 00438-2022.
Publication 2023
Arousal Carbon dioxide Dyspnea Excessive Daytime Sleepiness Fatigue Headache Inhalation Intercostal Muscle Muscle Weakness Neurologists Nose Patients Pressure Pressures, Maximum Inspiratory Respiration Saturation of Peripheral Oxygen Signs and Symptoms, Respiratory Sleep Tests, Pulmonary Function Vital Capacity
5
Measuring Maximal Inspiratory Pressure
The maximum inspiratory pressure was determined as previously described [34 (link)]. At the mouth, the PImax was determined using residual volume and total lung capacity, respectively. A tube-type mouthpiece was linked to the pressure transducer (P23 ID, Gould Instrument Systems, Valley View, Ohio) through 60 cm of pressure tubing, and an air leak was created at the mouthpiece via a small hole (diameter = 1.6 mm) to reduce the contribution of buccal muscles during the manoeuvre. All manoeuvres were carried out while seated in a chair. To avoid tiredness, data collection was paced: five PImax exercises were conducted with one-minute rest intervals; patients rested for five minutes before doing an additional five PImax manoeuvres with one-minute rest intervals. The PImax trials were classified as those with the highest sustained negative and positive pressures, respectively, against an obstructed airway for 1 second. The PImax per cent predicted was determined using Black and Hyatt's prediction equations: PImax per cent predicted = 120 (0.25 age) for men.
Hamad S.H., Hadi A.H., Mohr M., Mahadevan S.P, & Kzar M.H. (2023). The Effect of Threshold Loading Training and an Innovative Respiratory Training Devices with Lower Torso Sports Training in Asthma Patients: A Randomized Trial. BioMed Research International, 2023, 3049804.
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Publication 2023
Fatigue Muscle Tissue Oral Cavity Patients Pressures, Maximum Inspiratory Transducers, Pressure Volume, Residual

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1
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3
Autospiro as 507 by Minato Medical Science
Sourced in Japan
The Autospiro AS-507 is a compact, automated spirometer designed for pulmonary function testing. It is capable of measuring various respiratory parameters, including forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and peak expiratory flow (PEF).
4
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The Vmax Auto Box is a laboratory equipment product that provides automated data collection and analysis capabilities. It is designed to streamline various laboratory processes and tasks.
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Methacholine is a laboratory reagent used in various research and diagnostic applications. It functions as a cholinergic agonist, acting on muscarinic acetylcholine receptors. The core function of methacholine is to induce a physiological response, typically used in assessing airway responsiveness.
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More about "Pressures, Maximum Inspiratory"

Maximum inspiratory pressures (MIP) are a crucial measure of respiratory muscle strength and function.
This metric provides valuable insights into the overall health and performance of the respiratory system.
MIP reflects the maximum force or tension generated by the inspiratory muscles during inhalation, offering important information about respiratory disorders such as airflow limitation, neuromuscular diseases, and other respiratory conditions.
Accurate measurement of MIP is essential for the diagnosis, monitoring, and treatment of these respiratory issues.
Specialized equipment like MicroRPM, Pony FX, Autospiro AS-507, Vmax Auto Box, MyLab Twice, and Micro MRC can be used to precisely assess MIP.
These devices leverage technologies such as Methacholine and MasterScreen Body to capture reliable MIP data.
Understanding MIP is crucial for optimizing respiratory healthcare and research.
By leveraging the power of AI-driven platforms like PubCompare.ai, researchers and clinicians can enhance the reproducibility and accuracy of their MIP studies.
PubCompare.ai helps locate relevant protocols from literature, preprints, and patents, enabling the identification of the best practices and products for MIP assessment.
Whether you're investigating respiratory conditions, evaluating the efficacy of treatments, or exploring the underlying mechanisms of respiratory function, understanding maximum inspiratory pressures (MIP) is a key component of your research.
Explore the latest advancements in MIP measurement with tools like AAM377 and SpiroUSB, and unlock the full potential of your respiratory research with the help of PubCompare.ai.