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Valsalva Maneuver

The Valsalva Maneuver is a physiological technique involving a forced expiration against a closed airway, typically used to assess cardiovascular function and intrathoracic pressure changes.
This maneuver can help diagnose various medical conditions and is a valuable tool in research and clinical settings.
By understanding how to properly perform the Valsalva Maneuver and utilizing PubCompare.ai's protocol comparison tools, researchers can optimize their studies for reproducibility and accuracy, boosting the quality and impact of their work.

Most cited protocols related to «Valsalva Maneuver»

Under a Clinical Trial Agreement ANSAR supplied an ANX 3.0 device for clinical evaluation. ANSAR did not participate in any way in the design or conduct of the study or in the interpretation of the results. The testing procedure was conducted according to the company’s instructions and done by or under the supervision of personnel certified by ANSAR to carry out the testing protocol.
Electrocardiographic leads were attached and an automated arm blood pressure cuff applied. The electrocardiogram was used for power spectral analysis of heart rate variability and trans-thoracic electrical impedance for analysis of respiratory rate variability [6 (link)]. The ANX 3.0 gives instructions to subjects for the stages of the testing—baseline relaxed breathing for 5 minutes while sitting, deep breathing for 1 minute, return to baseline breathing for 1 minute, 5 Valsalva maneuvers, return to baseline for 2 minutes, and standing for 5 minutes.
A parameter termed RFa was calculated as the area within a 0.12 Hz bin of the spectrum centered at the fundamental respiratory frequency. The fundamental respiratory frequency, in breaths per second, is the frequency of the highest peak of the respiratory rate variability spectrum. In a healthy individual this frequency corresponds to the inverse of the respiratory rate during resting breathing. LFa was calculated from the LF component of the heart rate variability after taking into account RFa [6 (link)]. The exact calculations made by the ANSAR device were not available to us.
Based on the obtained LFa and RFa values the ANSAR device reports diagnostic implications and recommendations about possible treatments. “Sympathetic withdrawal” is reported if the standing:baseline ratio of LFa is less than 0.9. OH is diagnosed if a decrease of more than 20 mm Hg in systolic blood pressure or more than 10 mm Hg in diastolic pressure is found after 2 minutes of standing. If there is OH and the heart rate increases during standing, then the OH is reported as non-neurogenic; otherwise the OH is reported as neurogenic. A drop in blood pressure that is insufficient to satisfy criteria for OH is reported as “orthostatic intolerance.” If the blood pressure decreases by less than 5 mm Hg or the heart rate increases by less than 30 bpm, the diagnosis is possible “pre-clinical orthostatic intolerance.”
Publication 2010
Ansar Blood Pressure Cardiography, Impedance Diagnosis Electrocardiography Medical Devices Neurogenesis Pressure, Diastolic Rate, Heart Respiratory Rate Supervision Systolic Pressure Valsalva Maneuver

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Publication 2016
Common Cold Dietary Supplements Healthy Volunteers Pressure Sphygmomanometers Valsalva Maneuver Wrist
After obtaining study approval from the University of Utah Health Sciences Center Institutional Review Board, informed consent was collected from seven volunteers undergoing standard urodynamic testing. A sterile wireless Gen2 IVT and standard rectal balloon catheter was placed in each study participant by a member of the clinical research team. Each participant performed a series of coughs followed by a Valsalva maneuver both in the seated and standing position. Rectal balloon IAP readings were recorded at 15 Hz using clinical cystometry software (Laborie Medical Technologies) under a standard bladder volume of 200 ml. Wireless IVT pressure measurements were taken at 30 Hz using the Zarlink ADK base station and custom laptop software. Results of each transducer were plotted and compared.
Publication 2011
Catheters Cough Ethics Committees, Research Pressure Rectum Sterility, Reproductive Transducers Urinary Bladder Urodynamics Valsalva Maneuver Voluntary Workers
The Value of Urodynamic Evaluation (VALUE) study, an 11-center, randomized, noninferiority trial, compared the results among women who underwent an office evaluation without urodynamic testing (evaluation-only group) with those among women who underwent urodynamic testing in addition to the office evaluation (urodynamic-testing group) before their planned surgery. Details of the study design and methods have been published previously,9 (link) and the protocol is available with the full text of this article at NEJM.org.
Women presenting with urinary incontinence underwent a standardized basic office evaluation and were eligible for the study if they were 21 years of age or older, had a history of symptoms of stress urinary incontinence for at least 3 months, and had a score on the Medical, Epidemiological, and Social Aspects of Aging (MESA) questionnaire for stress urinary incontinence that was greater than the score on this questionnaire for urgency incontinence,10 (link) a postvoiding residual urine volume of less than 150 ml, a negative urinalysis or urine culture, a clinical assessment of urethral mobility, a desire for surgery for stress urinary incontinence, and a positive provocative stress test (defined as an observed transurethral loss of urine that was simultaneous with a cough or Valsalva maneuver at any bladder volume). Exclusion criteria were previous surgery for incontinence, a history of pelvic irradiation, pelvic surgery within the previous 3 months, and anterior or apical pelvic-organ prolapse of 1 cm or more distal to the hymen. Eligible patients were invited to participate in the study and asked to provide consent before any urodynamic testing was performed. After written informed consent had been obtained, study surgeons recorded their diagnoses on a comprehensive checklist of clinical diagnoses.
Patients were randomly assigned to a study group with the use of an automated randomization system stratified according to surgeon; more than 90% of the surgeons were fellowship-trained. Women in the urodynamic-testing group underwent noninstrumented uroflowmetry with a comfortably full bladder, filling cystometry with Valsalva leak-point pressures, and a pressure-flow study. Urethral pressure profilometry or urodynamic testing with the use of video was permitted if it was routinely performed as part of the pre-operative investigation at the study site. Testing followed the Good Urodynamic Practice guidelines of the International Continence Society,11 (link) and interpretation conformed to International Continence Society nomenclature.12 (link) After interpretation of the urodynamic tests, study physicians again completed the same comprehensive checklist of clinical diagnoses without viewing their previous entries. At office visits 3 and 12 months after treatment, outcome data were obtained by study personnel who were unaware of the group assignments.
The protocol was approved by the institutional review board at each site, and an independent data and safety monitoring board reviewed the progress and safety of the study. The third author, the senior statistician for the study, vouches for the accuracy of the reported data and for the fidelity of the study to the protocol.
Publication 2012
Aftercare Clinical Trials Data Monitoring Committees Cough Diagnosis Ethics Committees, Research Exercise Tests Fellowships Hymen Office Visits Operative Surgical Procedures Patients Pelvic Organ Prolapse Pelvis Physicians Pressure Radiotherapy Range of Motion, Articular Safety Surgeons Urethra Urinalysis Urinary Bladder Urinary Incontinence Urinary Stress Incontinence Urine Urodynamics Valsalva Maneuver Volume, Residual Woman
Ejection fraction was measured by quantitative 2-D methodology, as previously reported. 11 (link) Systolic dysfunction was defined as ejection fraction <50%. Decreased ejection fraction was defined as a decrease of >7.5% (i.e., 1 SD decrease).
Diastolic function was assessed by pulse wave Doppler examination of mitral flow (before and during Valsalva maneuver), pulmonary venous flow, and Doppler imaging of the medial mitral annulus.11 (link), 19 (link), 25 –28 (link) Diastolic dysfunction was graded on a four-point ordinal scale: 1) normal; 2) mild diastolic dysfunction = abnormal relaxation without increased LV end-diastolic filling pressure (decreased E/A ratio <0.75); 3) moderate or “pseudonormal” diastolic dysfunction = abnormal relaxation with increased LV end-diastolic filling pressure (E/A 0.75 to 1.5, deceleration time >140 ms, plus 2 other Doppler indices of elevated end-diastolic filling pressure); 4) or severe diastolic dysfunction = advanced reduction in compliance, (i.e. markedly increased stiffness) with restrictive filling (E/A ratio of >1.5, deceleration time <140 ms, and Doppler indices of elevated LV end-diastolic filling pressure). For participants in atrial fibrillation, diastolic function was classified as indeterminate unless restrictive physiology (E/A >1.5, deceleration time <140 ms) was present. Valvular heart disease was assigned for moderate to severe echocardiographic valvular stenosis or regurgitation.
Publication 2011
Atrial Fibrillation Deceleration Diastole Echocardiography physiology Pressure, Diastolic Pulse Rate Stenosis Systole Valsalva Maneuver Valve Disease, Heart Veins, Pulmonary

Most recents protocols related to «Valsalva Maneuver»

This study was a large single-center, prospective, controlled study. It was carried out in the Second Affiliated Hospital of Nanchang University. From March 2019 to March 2022, 132 “unexplained” dizziness patients and 121 patients with explained dizziness were enrolled, additionally,132 healthy volunteers without dizziness were recruited as normal controls. All patients recruited for the study voluntarily and signed an informed consent form. The ethics committee of the Second Affiliated Hospital of Nanchang University approved our research protocol [approval number (2019) 009].
We did a series of examinations (such as Dix–Hallpike maneuver, pure tone audiometry, an orthostatic hypotension test, a videonystagmography, caloric test parameters, video head impulse-test results, or vestibular-evoked potential measure of otolith function, carotid ultrasound, transcranial Doppler sonography, brain magnetic resonance imaging (MRI), magnetic resonance angiography (MRA), 24-hour dynamic electrocardiogram, echocardiography) on all patients with dizziness and detailed medical history inquiry, routine laboratory examinations, psychological/psychiatric evaluations, etc. After the burden of diagnosis and evaluation, the patient’s dizziness remains “unexplained”, which was considered for inclusion in the study. Also, the Valsalva maneuver is required, as it is the basis for determining whether RLS exists or not. Nevertheless, with a definite diagnosis of dizziness, including benign positional paroxysmal vertigo (BPPV), vestibular neuritis, vestibular migraine, Meniere’s disease, bilateral vestibular dysfunction, vestibular paroxysm, orthostatic hypotension, stroke, cerebellar ataxia, sudden deafness, cervical spondylosis, cardiogenic dizziness and combined tumor, endocrine, blood system, liver or kidney failure, patients with psychiatric disorder (such as suicide idea, addict, etc.) and other possible dizziness diseases have been excluded from our study, as well as pregnant woman and pulmonary arteriovenous malformation (PAVF), patent ductus arteriosus (PDA) also have been excluded.
Publication 2023
Arteriovenous Malformation Audiometry, Pure-Tone Benign Paroxysmal Positional Vertigo Brain Caloric Tests Cerebellar Ataxia Cerebrovascular Accident Deafness, Sudden Diagnosis Echocardiography Electrocardiography Ethics Committees, Clinical Evoked Potentials Head Impulse Test Healthy Volunteers Hemic System Hypotension, Orthostatic Kidney Failure Liver Lung Magnetic Resonance Angiography Meniere Disease Mental Disorders Migraine Disorders Neoplasms Otoconia Patent Ductus Arteriosus Patients Physical Examination Pregnant Women Spondylosis, Cervical System, Endocrine Ultrasonography, Carotid Arteries Ultrasonography, Doppler, Transcranial Valsalva Maneuver Vestibular Labyrinth Vestibular Neuronitis
The following activities were performed: leg extension (quadriceps) and leg press (quadriceps, gluteus, hamstrings, and calf muscles). Before the test, 12 repetitions with a modest weight were performed to mitigate learning effects. All participants completed the 1 min time limit on two attempts. Between repetitions, 1–2 minutes of relaxation were allowed. The Valsalva manoeuvre was avoided, and the proper technique for doing each muscle group's workout was emphasized [35 (link)].
Publication 2023
Buttocks Hamstring Muscle Muscle Tissue Quadriceps Femoris Valsalva Maneuver
All of the patients with PD underwent a standardized evaluation of cardiovascular autonomic function, as described by Low [16 (link)]. The testing was performed in the “off” state. The tests included detecting the heart rate response to deep breathing (HRDB), the Valsalva maneuver (VM), and the 5-min head-up tilt test. After the cardiovascular autonomic testing, the sudomotor function was then assessed using the Sudoscan following a previously described method [4 (link)]. No coffee, food, alcohol, or nicotine was permitted within the 4 h before the tests. Patients on medications known to cause orthostatic hypotension or to otherwise affect autonomic testing results were asked to stop the drug for five half-lives if it was not harmful to the patient’s well-being.
Heart rate (HR) was derived from continuously recorded standard three-lead ECG (Ivy Biomedical, model 3000; Branford, CT) while continuous blood pressure (BP) was recorded using beat-to-beat photoplethysmographic recordings (Finameter Pro, Ohmeda; Englewood, OH, USA). Subsequently, the parameters of the HRDB and the Valsalva ratio (VR) were obtained through the computation conducted by Testworks (WR Medical Electronics Company, Stillwater, MN). The detailed computation is described by Low [16 (link)]. In addition, baroreflex sensitivity (BRS) was derived from changes in the HR and the blood pressure during the early phase II of VM by applying the least-squares regression analysis (BRS_VM). As for the sympathetic sudomotor function, the ESCs of the hands and feet were obtained using the Sudoscan. The scoring system for the Sudoscan was modified from the original CASS scores for sudomotor domains [1 (link)]. AN was defined as a minimum score of 1 in at least two of the CASS domains (cardiovagal, sudomotor, or adrenergic) or a minimum score of 2 in one domain according to Low’s study [17 (link)]
Publication 2023
6-chloropenicillanic acid S-sulfoxide Adrenergic Agents Baroreflex Blood Pressure Cardiovascular Physiological Phenomena Cardiovascular System Coffee Enhanced S-Cone Syndrome Ethanol Food Foot Head Heart Hypersensitivity Hypotension, Orthostatic Nervous System, Autonomic Nicotine Patients Pharmaceutical Preparations Rate, Heart Respiratory Rate Valsalva Maneuver
Postoperative clinical evaluation was done with Chicago Chiari Outcome Scale (CCOS), includes pain, non-pain symptoms, functionality, and complications), and then categorized as improved (score 13–16), unchanged (score 9–12), or worse (4 (link)–8 (link)) based on the outcome score (9 (link)). This evaluation was made at 24 months postoperatively. According to the improvement in postoperative CCOS scores, patients will be grouped according to their preoperative ONSD values (increased intracranial pressure) using the ROC curve.
Preoperative headache was obtained by retrospective review of patient files. Characteristics such as the type of headache (headache increasing with cough), localization, severity, frequency, and the number of days of the month were determined. Postoperative headache assessment was made 1 year or more after surgery, by completing a questionnaire during a telephone interview or hospital visit. In the postoperative evaluation, it was asked to evaluate the severity of pain numerically (0 = no pain, 10 = the most severe pain), and also the localization of the pain, its frequency, and whether medication was taken, pain had changed after the surgical procedure (worsened, not changed, improved). Headache semiology was decided according to the International Classification of Headache Disorders 3rd edition (ICHD-3) (10 (link)). Typical headache attributable to CIM (according to the ICHD-3 diagnostic criteria, according to section) was described as a (sub-)occipital headache lasting seconds to a maximum of 5 min, triggered by coughing, laughing, or other Valsalva-type maneuvers.
Publication 2023
BAD protein, human Diagnosis Headache Headache Disorders Neoplasm Metastasis Operative Surgical Procedures Pain Patients Pharmaceutical Preparations Primary Cough Headache Severity, Pain Valsalva Maneuver
Totally, 26 males with bilateral varicocele (grade 2 or grade 3) and 20 healthy males were enrolled. All participants were examined in the standing positions, and the diagnosis standards and methods of varicocele included was visible swelling of the scrotum, and palpation of the spermatic cord at rest and during the Valsalva maneuver. Moreover, the ultrasound criteria for diagnosing a varicocele was spermatic vein diameter ≥2 mm and retrograde blood flow. There three grades of varicocele by the clinical grading system: grade 0 (subclinical): non-palpable and visualized only by Color Doppler ultrasound (CDUS); grade 1: palpable only with Valsalva maneuver; grade 2: easily palpable but not visible; and grade 3: easily visible. According to abovementioned criteria, varicocele on either side of the spermatic vein was excluded in 20 control males (Wein, 2007 ).
Semen samples were collected in sterile containers from healthy males and bilateral varicocele patients by masturbation after 2–7 days of sexual abstinence. After liquefaction, the characteristics of sperm concentration, pH, sperm motility, and sperm morphology were examined using a computer-assisted semen analyzer (WL-9000 sperm analyzer, Beijing Weili New Century Technology Development Co., LTD., Beijing, China) according to WHO guidelines (Sun et al., 2018 (link)). All semen samples were centrifuged at 500 g for 5 min. Then, the seminal plasma and spermatozoa were separated and stored at −80°C until analysis.
Publication 2023
Blood Circulation Males Palpation Patients Scrotum Semen Sperm Spermatic Cord Sperm Motility Sterility, Reproductive Ultrasonography Ultrasounds, Doppler Valsalva Maneuver Varicocele Veins

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More about "Valsalva Maneuver"

The Valsalva Maneuver is a physiological technique that involves forcibly exhaling while keeping the mouth and nose closed.
This maneuver is commonly used to assess cardiovascular function and changes in intrathoracic pressure.
By understanding how to properly perform the Valsalva Maneuver and leveraging advanced tools like PubCompare.ai's protocol comparison features, researchers can optimize their studies for reproducibility and accuracy, leading to higher-quality and more impactful research.
The Valsalva Maneuver is a valuable diagnostic tool in various medical conditions, including cardiovascular, respiratory, and neurological disorders.
It can be used in conjunction with instruments like the SOMATOM Force CT scanner, Manoscan esophageal manometry system, Dinamap ProCare blood pressure monitors, IE33 Color Doppler Ultrasound System, and the Finometer PRO system to gather comprehensive data and insights.
Performing the Valsalva Maneuver correctly is crucial for obtaining reliable results.
Researchers can utilize PubCompare.ai's protocol comparison tools to ensure they are following the best practices from the literature, preprints, and patents.
This AI-driven platform can help identify the optimal procedures and methodologies, ultimately enhancing the reproducibility and accuracy of their studies.
By mastering the Valsalva Maneuver and leveraging PubCompare.ai's powerful insights, researchers can take their work to new heights.
This combination of physiological techniques and advanced analytical tools can lead to groundbreaking discoveries and push the boundaries of scientific understanding.
With the right approach, researchers can maximize the impact of their research and contribute to the advancement of their respective fields.