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Amputation

Amputation is the surgical removal of a limb or other body part.
It is commonly performed due to trauma, infection, or disease.
Amputation can significantly impact a person's mobility and quality of life, making it an important area of medical research.
Researchers utilize various protocols and strategies to optimize amputation outcomes, including evaluating pre-prints, patents, and published literature.
By leveraging advanced AI-driven comparison tools like PubCompare.ai, researchers can identify the most effective amputation protocols and drive their work forward with confidence.
This platform helps locate the best solutions, enabling informed decisions that enhance amputation research and improve patient care.
Expore the future of amputation management today!

Most cited protocols related to «Amputation»

Studies were included if they met the following inclusion criteria: 1) Prospective or retrospective cohort studies or randomised control trials, 2) Studies that included community dwelling older adults as the population of interest, 3) Studies that validated the original version of the TUG test, 4) Studies that recorded a subsequent fall. Studies were excluded if their population of interest was limited to patients with specific neurological or orthopaedic condition e.g. Parkinson’s disease, stroke, hip fracture or amputation of a lower limb. Studies were also excluded if they were limited to a population with a particular medical condition e.g. patients with chronic obstructive pulmonary disease. For the purposes of this review, we included studies where ≥80% of subjects were community dwelling and/or were described as self caring or independent. Studies where >20% of the subject population were described as institutionalised, living in nursing homes, residential care homes or geriatric inpatients were excluded. The definition of a subsequent fall was considered in the context of each individual study. We considered the following definition of a fall: ‘an unexpected event in which the patient comes to rest on the ground, floor or lower level as the reference standard [1 (link)] and variations of this definition were recorded in Table 1 that contains details of the included studies.
Two reviewers (EB, RG) read the titles and/or abstracts of the identified references and eliminated irrelevant studies. Studies that were considered eligible for inclusion were read fully in duplicate and their suitability for inclusion was independently determined by both RG and EB. Disagreement was managed by consensus. Data were extracted on study type and setting, patient demographics (age, gender) and clinical characteristics including relevant inclusion and exclusion criteria, person who administered the TUG, person who recorded the subsequent fall, the definition of a fall used. For the purposes of this paper, the unit of analysis was the patient or “faller” rather than each “fall” to avoid duplication bias. Authors were contacted by email to provide further information on patient cohorts where there was insufficient data provided. Studies that included data on the same patient cohort for more than one publication were only included once in the meta-analysis.
Publication 2014
Aged Amputation Cerebrovascular Accident Chronic Obstructive Airway Disease Gender Hip Fractures Inpatient Lower Extremity Patients
Over the 6‑month period covering April 2010 to September 2010, all patients admitted to one of our patient wards at the Division of General Surgery, Department of Surgery, Medical University of Vienna were included in this study.
The Division of General Surgery in our university hospital consists of the following teams and specializations: colorectal surgery, hepatobiliary surgery, endocrine surgery, upper gastrointestinal (GI) surgery (esophageal and stomach surgery), bariatric surgery, breast surgery, and pancreatic surgery.
The patient data were extracted by reviewing all discharge letters from that period taken from the digital archives.
Overall, 517 patients were admitted over this period, some repeatedly, leading to a total of 817 admissions. These 517 patients underwent 463 operations. The complications of these operations were then rated according to the Clavien-Dindo classification (Table 1). For easier use, the suffix “d” for permanent disability was not drawn upon.

Clavien-Dindo classification

GradeDefinition
Grade IAny deviation from the normal postoperative course without the need for pharmacological treatment, or surgical, endoscopic, and radiological interventions.Allowed therapeutic regimens are: drugs as antiemetics, antipyretics, analgetics, diuretics and electrolytes, and physiotherapy. This grade also includes wound infections opened at the bedside
Grade IIRequiring pharmacological treatment with drugs other than such allowed for grade I complications.Blood transfusions and total parenteral nutrition are also included
Grade IIIRequiring surgical, endoscopic, or radiological intervention
Grade IIIaIntervention not under general anesthesia
Grade IIIbIntervention under general anesthesia
Grade IVLife-threatening complication (including central nervous system complications) requiring IC/ICU management
Grade IVaSingle organ dysfunction (including dialysis)
Grade IVbMultiorgan dysfunction
Grade VDeath of a patient

According to Dindo et al. [6 (link)]

IC intermediate care, ICU intensive care unit

The operations were sorted according to the complexity ranking (eight groups) in the accounting system of the Austrian Chamber of Physicians (Table 2; [8 ]).

Operation groups (complexity according to the Austrian Chamber of Physicians)

Operation groupExamples
IAbscess incisions, secondary sutures, proctoscopy, skin biopsy
IIExcisions of atheromas, fibromas, lipomas, incisions of anal abscesses
IIIToe amputation, small lymph node extirpation, thoracic drainage, colonoscopy
IVTracheotomy, appendectomy, hernia operation, colostomy, gastrostomy, ERCP
VGastroenterostomy, interventions for recurrent hernia, Cimino fistula, radical varicose vein stripping
VIStrumectomy, cholecystectomy, splenectomy, hemicolectomy, reduction mammoplasty
VIIPartial pancreatectomy, subtotal colectomy, subsegmental and large liver resections
VIIIEsophageal resection, open surgery of aortic aneurysms, organ transplantation
Publication 2018
Amputation Antiemetics Antipyretics Anus Aortic Aneurysm Appendectomy Atheroma Bariatric Surgery Blood Transfusion Central Nervous System Cholecystectomy Colectomy Colostomy Dialysis Disabled Persons Diuretics Drainage Electrolytes Endocrine Surgical Procedures Fibroma Fingers Fistula Gastrointestinal Surgical Procedure Gastrostomy Hemicolectomy Hepatectomy Hernia Intensive Care Lipoma Lymph Node Excision Operative Surgical Procedures Organ Transplantation Pancreas Pancreatectomy Parenteral Nutrition, Total Patient Discharge Patients Pharmaceutical Preparations Pharmacotherapy Physicians Proctoscopy Skin Splenectomy Stomach Surgical Endoscopy Surgical Wound Sutures Therapeutics Therapy, Physical Thoracic Surgical Procedures Treatment Protocols Upper Gastrointestinal Tract Varices Wound Infection X-Rays, Diagnostic
This is a hybrid cohort-modelled cross-sectional multi-centre surveillance study to be conducted over a period of four years. Two cross-sectional surveys conducted three years apart on standalone representative samples of each of the three city-wide populations, using objective measures will permit estimation of the prevalence and trends of CMDs and their risk factors. Those enrolled in the first cross-sectional survey will be followed as a cohort in a three-year study to estimate (i) the incidence of new risk factors (such as obesity, hypertension, diabetes,); (ii) incidence of later-stage target organ diseases such as peripheral vascular disease, stroke, myocardial infarction, congestive heart failure, chronic stable angina, CKD, retinopathy, neuropathy, and amputation; (iii) assessment of health service utilisation and costs including hospitalisation and outpatient use and (iv) morbidity and mortality associated with CMDs.
The first cross-sectional survey has been completed with ongoing first year of cohort-follow-up. The survey was comprehensive, undertaking assessments of quality of Life (QoL), and socioeconomic burdens on individuals and families with regards to these diseases. Participants underwent anthropometric measurements, blood pressure (BP) assessment, and provided biochemical specimens. The cohort follow-up was limited to patient reports with recording of BP and anthropometry. CMDs and their complications were diagnosed using standard definitions and coded using the International Classification of Diseases 10 (ICD-10) codes.
The study sites are metropolitan urban settings with large, growing (due to continued births and migration from various parts of the country), and heterogeneous populations. Estimates suggest that population size in Chennai (4.68 million)
[36 ], Karachi (13 million)
[37 ], and Delhi (16.3 million)
[36 ], and the diversity in their composition make these cities current and future archetypes of rapid socio-economic, demographic, epidemiologic, and nutrition/lifestyle transitions in the South-Asian region.
Publication 2012
Amputation Autosomal Dominant Craniometaphyseal Dysplasia Blood Pressure Cerebrovascular Accident Congestive Heart Failure Diabetes Mellitus Genetic Heterogeneity High Blood Pressures Hybrids Myocardial Infarction Obesity Outpatients Patients Peripheral Vascular Diseases Population Group Retinal Diseases South Asian People Stable Angina
Recruitment of participants was performed through resident associations, older adult meetings and preventive care establishments in Nishinomiya, Hyogo Prefecture and Ikeda, Osaka Prefecture and the town of Ikaruga, in Nara. The participants included 123 older adults (31 men, 92 women) aged 65 years or older (mean 75.0 ± 5.3 years) who had not received a Certification of Needed Support and Long-Term Care for older adults.
Exclusion criteria were: use of a body implant apparatus, including a pacemaker or artificial joint; any condition that presented a clear physical disability (bone fracture, amputation, difficulty walking); severe dementia (that would create difficulty with understanding instructions) or a severe heart condition not controlled by medication.
The study was approved (H26-11) by the Kio university research ethics committee.
Publication 2017
Aged Amputation Disabled Persons Ethics Committees, Research Fracture, Bone Heart Human Body Joints Long-Term Care Pacemaker, Artificial Cardiac Physical Examination Presenile Dementia Woman
Six self-reported outcome measures suited to prosthetic applications were assessed in this study. The Prosthetic Limb Users Survey of Mobility (PLUS-M) is an item bank developed to measure perceived mobility in people with lower limb amputation.28 -30 (link) The PLUS-M 12- and 7-item short forms were both administered in this study. Additionally, the PLUS-M computerized adaptive test (CAT) was administered to participants in Arm 3 (i.e., electronic-electronic). The Prosthesis Evaluation Questionnaire – Mobility Subscale (PEQ-MS) is a 12-item self-report measure assessing the ability to perform mobility tasks while using a lower limb prosthesis.31 (link) The Activities-Specific Balance Confidence Scale (ABC) is a 16-item instrument that measures respondents' confidence in performing basic ambulatory activities.32 (link) Recent Rasch analyses of the PEQ-MS33 (link) and ABC34 (link) resulted in similar recommendations to reduce the instruments' original visual analog scale (PEQ-MS) and 0-100 (ABC) response options to 5-point ordinal scales. These recommended modifications33 (link),34 (link) were incorporated into the instruments administered in this study. The Quality of Life in Neurological Conditions – Applied Cognition/General Concerns v1.0 (NQ-ACGC) is an item bank developed to measure general cognitive abilities, including memory, attention, and decision-making.35 (link) The 8-item NQ-ACGC short form was administered in this study. The Patient-Reported Outcomes Measurement Information System is a compilation of self-report instruments that measure eight symptom and quality of life constructs across patient populations: physical function, anxiety, depression, fatigue, sleep disturbance, social role satisfaction, pain interference, and pain intensity.36 (link),37 The PROMIS 29-Item Profile (PROMIS-29) was administered to participants in this study. The Socket Comfort Score (SCS) is a one-item measure of prosthetic socket comfort.38 (link) Participants' scores were calculated according to developers' instructions and used to evaluate test-retest reliability, MoA equivalence, SEM, and MDC. The ABC and PEQ-MS are scored from 0 to 4 (i.e., average score of all items), and the SCS is scored from 0 to 10 (i.e., score of the single SCS item). PLUS-M, PROMIS-29, and NQ-ACGC are scored on a T-score metric, which has a mean of 50 and standard deviation of 10.39
Publication 2016
Acclimatization Amputation Anxiety Attention Cognition Dyssomnias Fatigue Gomphosis Leg Prostheses Lower Extremity Memory Nervous System Disorder Pain Patients Physical Examination Population Group Prosthesis Range of Motion, Articular Satisfaction Severity, Pain Visual Analog Pain Scale

Most recents protocols related to «Amputation»

The study subjects (n = 13,750) were enrolled through cluster multistage and random sampling to community population from several districts of Shanghai in China in this cross-sectional study. The participants aged more than 18 years old were investigated in each center from May to September in 2016. Exclusion criteria included history of aortic dissection, history of amputation surgery, atrial fibrillation, mental disorder or lack of compliance. After the subjects with incomplete data or exclusion criteria were removed, there were totally 13,144 participants left (Fig. 1).

Flow chart of subjects enrollment

The study complied with the Declaration of Helsinki. It was also approved by the ethics committee of Shanghai Jiao Tong University and informed consent was obtained from all the participants prior to enrollment.
Publication 2023
Amputation Atrial Fibrillation Dissecting Aneurysms Ethics Committees Mental Disorders
For this pilot study, we chose patients in Tangdu Hospital and Xi’an Gaoxin Hospital with limb motor dysfunction caused by stroke 15-180 days after the onset (recovery period) and requiring rehabilitation training.
Patient inclusion criteria were as follows: (1) stroke diagnosed by computed tomography or magnetic resonance imaging within 90 days; (2) age between 30 and 75 years, male or female; (3) stable rehabilitation patients with limb motor dysfunction (with hemiplegic motor function evaluated according to the Brunnstrom upper or lower extremity grading stages II-VI) caused by stroke 15-180 days after its onset (recovery period); (4) cognition is clear and can follow the research protocol; (5) the patient can understand the study’s purpose, as well as showing sufficient compliance with the study protocol and signed the informed consent.
The following patients were excluded: (1) significant impairment of cognition and consciousness so that the Fugl-Meyer test could not be completed, (2) other significant limb lesions, such as fractures, severe arthritis, or amputation; (3) formation of limb joint contractures; (4) patients with disability, as specified by the International Classification of Functioning, Disability, and Health; (5) patients with a combination of severe primary diseases involving the cardiovascular, liver, kidney, and hematopoietic systems and mentally ill patients, as well as other circumstances that the investigator considers inappropriate to participate in this trial.
Publication 2023
Amputation Arthritis Cardiovascular System Cerebrovascular Accident Cognition Consciousness Contracture Disabled Persons Disorders, Cognitive Fracture, Bone Hematopoietic System Inpatient Joints Kidney Liver Lower Extremity Males Mentally Ill Persons Patients Protocol Compliance Rehabilitation Woman X-Ray Computed Tomography
Patients, hand surgeons, and hand therapists were identified as the key stakeholders. Adult patients with hand injuries were identified through fracture clinics at a UK trauma centre (Queen's Medical Centre, Nottingham). These injuries included fractures (of the phalanges, metacarpals, carpal bones, or distal radius or ulna), or injuries to any of the joints between these bones. We excluded complex hand injuries (i.e. ‘mangled hand’, amputations requiring replantation), primary nerve injuries, burns, and open tendinous injuries.
Surgeons and hand therapists who manage patients with the included injuries were eligible, with the requirement that they work at an independent practitioner level (i.e. consultant or equivalent) and have a subspecialty interest in injuries within the scope of the COS. Clinician participants were identified through established national and international clinical and research networks and professional societies. This involved email correspondence sent to the Secretariat of each of the member societies of the International Federation of Societies for Surgery of the Hand and the International Federation of Societies for Hand Therapy. We also publicized the study through the British Society for Surgery of the Hand (BSSH) newsletter, the British Association of Hand Therapists (BAHT) e-bulletin, the Centre for Evidence Based Hand Surgery Hand Surgery Evidence Updates, and via an announcement and brief presentation to the audience of the weekly Derby Pulvertaft webinar. Many of these clinicians have a role as clinical academics, with both a clinical and researcher perspective.
Publication 2023
Adult Amputation Bones Bones, Metacarpal Bones of Fingers Burns Carpal Bones Consultant Fracture, Bone Hand Injuries Injuries Joints Manual Therapies Nervousness Operative Surgical Procedures Patients Radius Surgeons Surgical Replantation Tendon Injuries Ulna
A literature search was performed in Cochrane, Embase, Medline/Pubmed, and PsycInfo databases until the end of March 2020 with the assistance of an information specialist (librarian). Free text, using keywords and synonyms for Lisfranc and Chopart amputation, including MESH terms, were used in the different searches of the databases. For MEDLINE/Pubmed, the following search strategy was used: partial foot amputation [tiab] OR Lisfranc [tiab] OR Chopart [tiab] OR trans-metatarsal amputation [tiab] OR midfoot amputation [tiab] OR forefoot amputation [tiab]. Adapted search strategies were used in the other databases (Appendix S1, Supplemental Digital Content, http://links.lww.com/MD/I612). Because this is a review, no ethical approval was necessary.
The search was limited to the English, German, and Dutch language, with no restrictions on publication date and patient age. Duplications were removed. Of the remaining publications titles and abstracts were assessed by 2 reviewers (GW and JG) independently.
Studies were included in this review if they reported on wound healing, the need for amputation at a more proximal level, and ambulation level after Lisfranc or Chopart amputation. Excluded from this review were editorials, (expert) reviews, letters to the editor, case reports, publications of which no full text was available after library requests, publications without result differentiation between Lisfranc and Chopart amputations, or not meeting the topic.
Cohen kappa and absolute agreement were calculated, as a measure for inter-observer agreement of study selection. In case of disagreement between observers, a consensus was reached by means of discussion. In case of doubt, the publication was included in the next round of full-text assessment. All included full-text publications were retrieved from the library and were assessed for the same inclusion and exclusion criteria, by the same observers. Again, the inter-observer agreement was calculated using Cohen kappa and an absolute agreement.
References from the included studies were screened for additional relevant studies missed in the database search. These studies were assessed as described above.
All included studies were assessed according to 12 quality evaluation items:[13 (link)] report of source information, report of inclusion criteria, report of exclusion criteria, report of the time frame of recruitment, report of recruitment setting, subjects consecutively recruited, validated questionnaire, (patients were all analyzed, control or assessment of confounding, report of missing data, missing data imputed, and report of response rate. Each item was scored “1” if the criterion item was met, and “0” if the criterion item was not met.
Two reviewers (GW and PD) independently assessed the quality of the included studies. In a consensus meeting the scores were compared. When there was disagreement, a consensus was reached by means of discussion. In case of persistent disagreement, a third reviewer (JG) gave the final judgment. Again, Cohen kappa and absolute agreement were calculated.
Publication 2023
Amputation cDNA Library Foot Information Specialists Metatarsal Bones Patients Reading Frames
Macrovascular complications are composed of cardiovascular disease, cerebrovascular disease, and peripheral arterial occlusive disease (PAOD); whereas microvascular complications comprise neuropathy, nephropathy, and retinopathy [1 (link), 2 (link)]. In this study, patients with any one of the listed conditions including coronary heart disease, myocardial ischemia and/or infarction, angina, congestive heart failure, arrhythmia, and a history of percutaneous transluminal coronary angioplasty (PTCA) or coronary artery bypass graft surgery (CABG) were referred to have cardiovascular disease. The cerebrovascular disease is defined as a group of diseases including transient ischemic attack (TIA), ischemic stroke, and hemorrhagic stroke. PAOD is defined as a composite of following status, such as having symptom of intermittent claudication, abnormal foot assessment with reduced or absent pulse over dorsalis pedis artery and/or posterior tibial artery, and a history of percutaneous transluminal angioplasty (PTA), peripheral artery bypass surgery, or amputation. Moreover, diabetic polyneuropathy comprises patients who had neurologic symptoms or aberrant neurologic physical examinations such as decrease/loss of vibratory or pinprick sensation tested by hemi-quantified tuning fork and single-stranded nylon, respectively, on either foot. Patients with diabetic retinopathy are defined as those who had one of the following conditions including macular degeneration, non-proliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR), blindness, or receiving laser therapy of retina in the past. Estimated glomerular filtration rate (eGFR), expressed in ml/min/1.73 m2, was calculated using the equation from Modification of Diet in Renal Disease (MDRD) [22 (link)]. Finally, diabetic kidney disease (DKD) in this study was defined as eGFR < 60 ml/min/1.73 m2 or albuminuria defined as a spot urine albumin to creatinine ratio (UACR) ≥ 30 mg/g.
Publication 2023
Age-Related Macular Degeneration Albumins Amputation Angina Pectoris Arterial Occlusive Diseases Arteries Blindness Cardiac Arrhythmia Cardiovascular Diseases Cerebrovascular Disorders Congestive Heart Failure Coronary Arteriosclerosis Coronary Artery Bypass Surgery Creatinine Diabetic Nephropathy Diabetic Polyneuropathies Diabetic Retinopathy Dietary Modification Foot Glomerular Filtration Rate Heart Disease, Coronary Hemorrhagic Stroke Infarction Intermittent Claudication Kidney Diseases Laser Therapy Neurologic Examination Neurologic Symptoms Nylons Operative Surgical Procedures Patients Percutaneous Transluminal Angioplasty Percutaneous Transluminal Coronary Angioplasty Peripheral Vascular Diseases Pulse Rate Retina Retinal Diseases Stroke, Ischemic Tibial Arteries, Posterior Transient Ischemic Attack Urine Vibration

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More about "Amputation"

Amputation, the surgical removal of a limb or other body part, is a critical area of medical research and practice.
It is commonly performed due to trauma, infection, or disease, and can significantly impact a person's mobility and quality of life.
Researchers in this field utilize various protocols and strategies to optimize amputation outcomes, including evaluating pre-prints, patents, and published literature.
By leveraging advanced AI-driven comparison tools like PubCompare.ai, researchers can identify the most effective amputation techniques and drive their work forward with confidence.
This platform helps locate the best solutions, enabling informed decisions that enhance amputation research and improve patient care.
Expore the future of amputation management today! Key topics in amputation research include prosthetics and assistive devices, pain management, wound healing, and rehabilitation.
Researchers may also explore the use of anesthetics like MS-222 (Tricaine) and preservatives like TRIzol reagent during the surgical process.
Bioinformatics tools like SAS 9.4 and Prism 9 can be utilized to analyze data and optimize outcomes.
Whether you're working on improving amputation techniques, developing new prosthetic technologies, or exploring ways to enhance patient recovery, PubCompare.ai can help you stay ahead of the curve.
Discover the power of this AI-driven platform and take your amputation research to the next level.
Expore the future of amputation management today!