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Bariatric Surgery

Bariatric Surgery: A specialized field of surgery focused on the treatment of obesity and its related health conditions.
This procedure involves modifying the digestive system to induce weight loss, often through techniques like gastric bypass, sleeve gastrectomy, or adjustable gastric banding.
Bariatric surgery has been shown to be an effective long-term solution for individuals struggling with severe obesity, leading to significant weight loss and improvements in comorbidities like type 2 diabetes, hypertension, and heart disease.
Patients undergo a comprehensive evaluation and tailored treatment plan to ensure safe and successful outcomes.
Reasearch in this area continues to evolve, exploring new surgical techniques and adjunct therapies to optimie results and minimize risks.

Most cited protocols related to «Bariatric Surgery»

The Clinformatics™ Data Mart captures administrative health claims across the United States for members of a large national managed care company affiliated with OptumInsight (Eden Prairie, MN). We examined claims from January 1, 2012 to June 30, 2015 among adults ages 18 to 64 to capture surgical procedures performed between 2013 and 2014 to account for the 12-month preoperative and 6-month postoperative study period. We included only individuals with continuous medical and prescription drug coverage to evaluate the complete health care experience. We excluded patients ages 18 and younger, as well as patients older than 64 years due to incomplete capture of Medicare Part D prescriptions claims data. The study was deemed exempt from review by the University of Michigan Institutional Review Board.
We selected 13 common elective surgical procedures, and categorized these into minor and major groups based on prior literature. Minor surgical procedures included varicose vein removal, laparoscopic cholecystectomy, laparoscopic appendectomy, hemorrhoidectomy, thyroidectomy, transurethral prostate surgeries, and parathyroidectomy. Major surgical procedures included ventral incisional hernia repair, colectomy, reflux surgery, bariatric surgery, and hysterectomy. We identified patients undergoing surgery using Current Procedural Terminology (CPT) or International Statistical Classification of Diseases and Related Health Problems (ICD9_ procedure codes (Supplemental Table 1).
We sought to determine new persistent opioid use after surgery, and included only patients who filled an opioid prescription fill either in the month prior to surgery or within two weeks after discharge. Comparable to previous studies of opioid naïve surgical populations,7 (link),8 patients who had filled one or more prescriptions for opioids 12 months to 31 days prior to their surgical procedure were excluded from the analysis (Figure 1). To account for prescriptions provided preoperatively for postoperative pain control, patients filling opioids in the 30 days prior to surgery were included, and prescriptions filled in this time was included as a covariate in the analyses. Lastly, we excluded patients who underwent additional surgical procedures during the study period using subsequent procedural codes for anesthesia in the 6-month postoperative period.
As a comparison cohort of patients who did not undergo surgery, we identified a random 10% sample patients ages 18 to 64 years of age who did not undergo surgery in the study period We included only patients in the nonoperative group who did not fill an opioid prescription during a 12 month period and did not have any codes for surgical procedures or anesthesia during this period. These patients were then given a random date of surgery. No patients had an opioid fill in the year prior to their fictitious surgery date nor did they have any anesthesia codes in the 6 months following their fictitious surgery date.
Publication 2017
Adult AN 12 Anesthesia Appendectomy Bariatric Surgery Cholecystectomy, Laparoscopic Colectomy Elective Surgical Procedures Ethics Committees, Research Hemorrhoidectomy Herniorrhaphy Hysterectomy Laparoscopy Managed Care Minor Surgical Procedures Operative Surgical Procedures Opioids Pain, Postoperative Parathyroidectomy Patient Discharge Patients Prescription Drugs Prostate Surgery, Day Thyroidectomy Varices Youth
Subjects were recruited from an obesity treatment center in a university hospital in Taiwan. The obesity treatment center personnel comprised a multi-disciplinary team, and included a surgeon, internal physician, psychiatrist, urologist, obstetrics and gynecology doctor, nurse, case manager, dietician, and physical activity director. The obesity treatments in this center included non-surgical procedures: meal replacement, pharmacotherapy, psychiatric bio-feedback treatment and intra-gastric balloon, and surgery: bariatric surgery (sleeve, band, Roux-en-Y gastric bypass). First of all, the patients made up their mind as to the treatment modality. However, the patients who wanted to receive bariatric surgery had to meet the criteria of morbid obesity. They then needed to undergo a complete pre-operation evaluation, including a psychiatric evaluation. Our hospital has a committee in charge of determining whether the patients are eligible for bariatric surgery.
Patients received a complete physical evaluation during their first visit, and also completed two questionnaires: the Taiwanese Depression Questionnaire (TDQ) and the Chinese Health Questionnaire (CHQ). The TDQ is a 0-3-point, 18-question questionnaire used to screen clinical depressive disorder.
[22 (link)]. The cut-off point in the community population is 18/19 points. The CHQ
[23 (link)] is a 12-question, 2-reverse questions, 0-1-point questionnaire for screening “minor psychiatric disorders” such as anxiety disorder. The cut-off point in community surveys screening minor mental disorders is 4/5 points.
To avoid false negative results, we lowered the cut-off points for the CHQ and TDQ in our clinical practice. Those patients with CHQ <3 and TDQ <13 were regarded as having no psychiatric disorder. If any of the two scores were above the cut-off point (i.e., CHQ ≧3 or TDQ ≧13, or both), the patients would be referred to psychiatrists for further evaluation. The lifetime psychiatric diagnosis was made based on the psychiatrist’s diagnostic interview, using the Structured Clinical Interview for the DSM-IV (SCID).
We recruited all patients that visited the obesity treatment center of E-Da Hospital from January 2007 to December 2010. The exclusion criteria were age younger than 18 years, having incomplete BMI, TDQ or CHQ data, and refusal of psychiatric interview when needed.
All analyses were performed with the Statistical Package for Social Sciences, SPSS Version 17.0. The chi-square test was used to compare differences for categorical variables and the t-test was used to compare differences for continuous variables. The level of statistical significances was 0.05, two-tailed. Logistic regression was applied to examine whether BMI was associated with a psychiatric disorder.
This study was approved by the Institutional Review Board of E-Da Hospital, Taiwan (EMPR-098-073). The study design and performance complied with the Declaration of Helsinki.
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Publication 2013
Anxiety Disorders Bariatric Surgery Biofeedback Case Manager Chinese Diagnosis Diagnosis, Psychiatric Dietitian Disorder, Depressive Ethics Committees, Research Gastric Balloon Gastrojejunostomy Hospital Administration Mental Disorders Nurses Obesity Obesity, Morbid Patients Pharmacotherapy Physicians Psychiatrist Surgeons Urologists Youth

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Publication 2013
Bariatric Surgery Biliopancreatic Diversion Duodenum Gastrectomy Gastric Bypass Gastrojejunostomy Laparoscopy Operative Surgical Procedures Patients Stomach Surgeons
Over the 6‑month period covering April 2010 to September 2010, all patients admitted to one of our patient wards at the Division of General Surgery, Department of Surgery, Medical University of Vienna were included in this study.
The Division of General Surgery in our university hospital consists of the following teams and specializations: colorectal surgery, hepatobiliary surgery, endocrine surgery, upper gastrointestinal (GI) surgery (esophageal and stomach surgery), bariatric surgery, breast surgery, and pancreatic surgery.
The patient data were extracted by reviewing all discharge letters from that period taken from the digital archives.
Overall, 517 patients were admitted over this period, some repeatedly, leading to a total of 817 admissions. These 517 patients underwent 463 operations. The complications of these operations were then rated according to the Clavien-Dindo classification (Table 1). For easier use, the suffix “d” for permanent disability was not drawn upon.

Clavien-Dindo classification

GradeDefinition
Grade IAny deviation from the normal postoperative course without the need for pharmacological treatment, or surgical, endoscopic, and radiological interventions.Allowed therapeutic regimens are: drugs as antiemetics, antipyretics, analgetics, diuretics and electrolytes, and physiotherapy. This grade also includes wound infections opened at the bedside
Grade IIRequiring pharmacological treatment with drugs other than such allowed for grade I complications.Blood transfusions and total parenteral nutrition are also included
Grade IIIRequiring surgical, endoscopic, or radiological intervention
Grade IIIaIntervention not under general anesthesia
Grade IIIbIntervention under general anesthesia
Grade IVLife-threatening complication (including central nervous system complications) requiring IC/ICU management
Grade IVaSingle organ dysfunction (including dialysis)
Grade IVbMultiorgan dysfunction
Grade VDeath of a patient

According to Dindo et al. [6 (link)]

IC intermediate care, ICU intensive care unit

The operations were sorted according to the complexity ranking (eight groups) in the accounting system of the Austrian Chamber of Physicians (Table 2; [8 ]).

Operation groups (complexity according to the Austrian Chamber of Physicians)

Operation groupExamples
IAbscess incisions, secondary sutures, proctoscopy, skin biopsy
IIExcisions of atheromas, fibromas, lipomas, incisions of anal abscesses
IIIToe amputation, small lymph node extirpation, thoracic drainage, colonoscopy
IVTracheotomy, appendectomy, hernia operation, colostomy, gastrostomy, ERCP
VGastroenterostomy, interventions for recurrent hernia, Cimino fistula, radical varicose vein stripping
VIStrumectomy, cholecystectomy, splenectomy, hemicolectomy, reduction mammoplasty
VIIPartial pancreatectomy, subtotal colectomy, subsegmental and large liver resections
VIIIEsophageal resection, open surgery of aortic aneurysms, organ transplantation
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Publication 2018
Amputation Antiemetics Antipyretics Anus Aortic Aneurysm Appendectomy Atheroma Bariatric Surgery Blood Transfusion Central Nervous System Cholecystectomy Colectomy Colostomy Dialysis Disabled Persons Diuretics Drainage Electrolytes Endocrine Surgical Procedures Fibroma Fingers Fistula Gastrointestinal Surgical Procedure Gastrostomy Hemicolectomy Hepatectomy Hernia Intensive Care Lipoma Lymph Node Excision Operative Surgical Procedures Organ Transplantation Pancreas Pancreatectomy Parenteral Nutrition, Total Patient Discharge Patients Pharmaceutical Preparations Pharmacotherapy Physicians Proctoscopy Skin Splenectomy Stomach Surgical Endoscopy Surgical Wound Sutures Therapeutics Therapy, Physical Thoracic Surgical Procedures Treatment Protocols Upper Gastrointestinal Tract Varices Wound Infection X-Rays, Diagnostic
All patients who were enrolled in the bariatric surgery program in the Center for Nutrition and Weight Management at Geisinger Clinic were offered participation in an ongoing research program in obesity using clinical data accessed through the electronic health record that was approved by the Geisinger Clinic Institutional Review Board. For this study, a total of 2028 patients who underwent RYGB gastric bypass surgery from 01/01/2004 through 07/02/2010 were included in the database. The bariatric surgery program consisted of a 6 to 12 month pre-operative assessment and preparation period that included a diet-induced weight loss target of 10% of body weight. Patients were followed at approximately 1, 3, 5, and 12 months following RYGB surgery and every 12 months thereafter. All clinical data were entered into the EpicCare® EHR (Verona, WI). The EpicCare® EHR integrates information from a variety of sources into a common interoperable database that includes patient demographics, vitals, clinical measures, problem list (based on ICD-9 codes), medical history, medication history, personal and family histories, encounters (e.g. office visits, hospitalizations, nurse encounters, telephone inquiries and specialty consultations), orders (e.g. labs, medications, imaging and procedures), appointments, digital imaging (e.g. MRI, CT, X-ray, medical photography), results (e.g. procedure reports, lab results, pathology reports), and billing and claims databases (detailed financial transactions associated with each clinical encounter). All data except laboratory results, which were fed directly to the EHR by the laboratory information system, were entered at the point-of-care including age, sex, height, and weight, lifestyle factors (e.g., smoking, alcohol, etc.), clinical measures (e.g., blood pressure), all orders (i.e., lab requests, prescriptions, imaging, and procedures) which require at least one indication (i.e., ICD-9 code), active use of all medications, and all co-morbidities. The schema for data acquisition is shown in Figure 1.
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Publication 2012
Bariatric Surgery Blood Pressure Diet Ethanol Ethics Committees, Research Fingers Gastric Bypass Hospitalization Nurses Obesity Office Visits Operative Surgical Procedures Patients Pharmaceutical Preparations Point-of-Care Systems Prescriptions Radiography

Most recents protocols related to «Bariatric Surgery»

Several clinical cohorts were included in the current study. This was approved by the Regional Committees for Medical and Health Research Ethics in Bergen (REK: 2010/502 and 2015/2343) and written consent was obtained from all participants. First, subcutaneous adipose tissue from liposuction aspirates of individuals undergoing plastic surgery was used for proteomic screening. Buffy coats from anonymous blood donors were used as blood samples and internal controls for the cell surface screening. For the 27-color flow cytometry analysis, matched fasting blood samples and subcutaneous- and visceral adipose tissue biopsies were obtained from 43 patients with obesity undergoing bariatric surgery at Voss Hospital. The clinical characteristics and biochemical measurements of this cohort are presented in Table 1.
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Publication 2023
Bariatric Surgery Biopsy BLOOD Blood Buffy Coat Cells Donors Flow Cytometry Obesity Patients Plastic Surgical Procedures Subcutaneous Fat Suction Lipectomy Visceral Fat
Subcutaneous adipose tissue and visceral adipose tissue biopsies obtained from bariatric surgery were immediately stored in Krebs-Ringer Phosphate (KRP) buffer until processing. The biopsies were cut into pieces and enzymatically digested with collagenase Type I (Life Technologies) for 1 hour at 37°C with constant shaking. The subcutaneous adipose tissue from liposuction was washed in 0.9% NaCl, diluted in KRP buffer and digested with Liberase (Roche). The dissolved tissues were filtered, and the stromal vascular cells (SVC) were isolated from the mature adipocytes and washed with Phosphate Buffered Saline (PBS). The liposuction SVC was freshly stained, whereas the SVC from biopsies were preserved in freezing media containing FBS and 10% DMSO and stored in liquid nitrogen until further flow cytometry experiments. Peripheral blood mononuclear cells (PBMC) were isolated from blood of bariatric surgery patients and healthy donors using density gradient centrifugation, as previously described (33 (link)).
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Publication 2023
Adipocytes Bariatric Surgery Biopsy BLOOD Blood Vessel Centrifugation, Density Gradient Collagenase, Clostridium histolyticum Donors Flow Cytometry Liberase Nitrogen Normal Saline Patients PBMC Peripheral Blood Mononuclear Cells Phosphates Saline Solution Stromal Cells Subcutaneous Fat Suction Lipectomy Sulfoxide, Dimethyl Tissues Visceral Fat

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Publication 2023
Adult Bariatric Surgery Ethnicity Face Hispanic or Latino Households Interviewers Obesity Reading Frames
We selected newspapers based in the UK and US. These countries are representative of the Anglo-Saxon world, yet have distinct socio-economic and healthcare contexts that might impact how the topic is framed in the media. Specifically, in the UK, resources for healthcare interventions are allocated through the National Health Service (NHS), whereas in the US the publicly financed Medicare and Medicaid health coverage coexists with privately financed coverage, which is unaffordable for many Americans. In both countries, pediatric obesity rates are high, and adolescent bariatric surgery has been available for some time. Consequently, obesity and bariatric surgery are being discussed not only in the scientific community but also in the national and regional media.
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Publication 2023
Adolescent Bariatric Surgery Health Services, National Obesity Pediatric Obesity
The search strategy yielded 537 articles (205 UK and 332 US newspaper articles), which were downloaded in Word format. Duplicates and articles reprinted in newspapers based in countries other than the US or the UK were excluded. Selection criteria were a focus on adolescent bariatric surgery and relevance for an analysis of media framing; i.e. articles limited to describing the results of a scientific study on adolescent surgery were excluded. Given the broad search, most articles were not relevant for our purpose. After assessment of all articles by the first author, 38 articles (26 from the UK and 12 from the US) were included (Fig. 1). The list of all included articles is presented in Supplementary Table 1.

PRISMA Flowchart of the study selection process

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Publication 2023
Adolescent Bariatric Surgery Operative Surgical Procedures

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TaqMan assays are a type of real-time PCR (polymerase chain reaction) technology developed by Thermo Fisher Scientific. They are designed for sensitive and specific detection and quantification of target DNA or RNA sequences. TaqMan assays utilize fluorescent probes and specialized enzymes to generate a measurable signal proportional to the amount of target present in a sample.
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More about "Bariatric Surgery"

Bariatric surgery, also known as weight loss surgery, is a specialized field of medicine focused on treating obesity and its associated health conditions.
This procedure involves modifying the digestive system to facilitate significant and sustained weight loss, often through techniques like gastric bypass, sleeve gastrectomy, or adjustable gastric banding.
Bariatric surgery has been shown to be an effective long-term solution for individuals struggling with severe obesity, leading to substantial weight loss and improvements in comorbidities like type 2 diabetes, hypertension, and cardiovascular disease.
Patients undergo a comprehensive evaluation and personalized treatment plan to ensure safe and successful outcomes.
Research in this area continues to evolve, exploring new surgical techniques and adjunct therapies to optimize results and minimize risks.
Techniques like the RNeasy Mini Kit, TaqMan assays, and the High Capacity RNA-to-cDNA Kit may be used to analyze genetic and molecular changes associated with bariatric surgery.
The Vacutainer System and RNAlater may be employed for sample collection and preservation, while the 7900HT Fast Real-Time PCR System could be utilized for gene expression analysis.
The SAS version 9.4 statistical software may be used to analyze data and draw insights from bariatric surgery studies.
Barriatric surgery has emerged as a transformative approach in the management of obesity, offering hope and improved quality of life for millions of individuals worldwide.
As research continues to advance, we can expect to see further refinements in surgical techniques, optimized patient selection, and enhanced long-term outcomes.