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Minimally Invasive Surgical Procedures

Minimally Invasive Surgical Procedures are a range of surgical techniques that aim to minimize tissue damage and patient recovery time.
These procedures utilize small incisions, specialized instruments, and advanced imaging technologies to perform complex operations with greater precision and reduced invasiveness.
By leveraging innovative approaches, surgeons can target specific areas of the body with minimal disruption to surrounding structures, leading to improved patient outcomes and faster healing.
This MeSH term encompasses a variety of minimally invasive techniques, such as laparoscopic, arthroscopic, and endovascular procedures, that have transformed modern surgery and enhanced the quality of patient care.

Most cited protocols related to «Minimally Invasive Surgical Procedures»

1
Benchmarking Methanogen Taxonomic Assignment
Cited 32 times
Benchmarking was performed on isolate sequences and on an amplicon test dataset. Twenty-four sequences of rumen and intestinal methanogens were selected for benchmarking with isolate sequences (see Table S2). The selected sequences were either exported from SILVA or are published as part of this study (see Table S2 for isolates). Analysis was performed on long length (>1,000 bp) sequences and on sequences of the V6–V8 variable regions of the 16S rRNA gene. Taxonomic assignment of sequences was carried out using the parallel_assign_taxonomy_blast.py script in QIIME, version 1.5. The three different reference databases used for taxonomic assignments of sequences were RIM-DB (File S1 and File S3), SILVA (release 111, Pruesse et al., 2007 (link)) and Greengenes (release GG_13_05, McDonald et al., 2012 (link)). QIIME-compatible SILVA and Greengenes databases were downloaded from http://qiime.wordpress.com. Specific options/files used for taxonomic assignments with SILVA were: –id_to_taxonomy Silva_111_taxa_map_full.txt and –blast_db Silva_111_full_unique.fasta; and with Greengenes: –id_to_taxonomy gg_13_5_taxonomy and -blast_db gg_13_5.fasta. Abundance tables were generated and only OTUs with a mean minimum relative abundance of 1% across all samples were retained.
A test set of amplicon sequence data was generated by combining the following sequence datasets (for accession numbers see Table S4). These datasets contain partial 16S rRNA gene sequences covering nucleotide positions 935–1,385 (Escherichia coli 16S rRNA nucleotide numbering (Brosius et al., 1978 (link))). Sequence data were processed using the QIIME package, version 1.5 (Caporaso et al., 2010 (link)). Reads were quality filtered and assigned to the corresponding sample by barcodes using the QIIME split_library.py script. Only reads with average quality scores >25 were included in the analysis. The resulting fna-files from all experiments were concatenated and denoised using combined flowgram-files, using the denoise_wrapper.py script with default settings (Reeder & Knight, 2010 (link)). The output was subjected to the inflate_denoiser_output.py script (default settings). Denoised sequence reads were chimera-checked with the QIIME script parallel_identify_chimeric_seqs.py, using the parameters –d 4 and –n 2, and using RIM-DB as the reference database. The chimeric sequences that were identified were removed from the dataset using the QIIME filter_fasta.py script. Subsequently, the denoised and chimera-checked dataset was processed with the QIIME pipeline. Sequences were clustered into operational taxonomic units (OTUs) used the default clustering method UCLUST (Edgar, 2010 (link)) with a sequence similarity cut-off of 99% (pick_otus.py option: -s 0.99). Abundance tables were generated and only OTUs with a mean minimum relative abundance of 1% across all samples were retained. Taxonomic assignment of representative sequences was carried out as described for the isolate sequences.
Seedorf H., Kittelmann S., Henderson G, & Janssen P.H. (2014). RIM-DB: a taxonomic framework for community structure analysis of methanogenic archaea from the rumen and other intestinal environments. PeerJ, 2, e494.
Publication 2014
Base Sequence Chimera DNA Library Escherichia coli Genes Intestines Methanobacteria Minimally Invasive Surgical Procedures Nucleotides Ribosomal RNA Genes RNA, Ribosomal, 16S Rumen
2
Finnish Helicopter Emergency Medical Service
Cited 12 times
Finland is a Nordic country with a population of 5.5 million and an area of 338,424 km2, thus making it the most sparsely populated country in the European Union. Healthcare is governed regionally by 21 hospital districts, each braced by one of the five university hospitals for tertiary care.
EMS in Finland are locally organized by the hospital districts. The system is publicly funded, including the dispatch centers and HEMS. Since 2012 HEMS is administered by a national administrative unit FinnHEMS Ltd., owned and governed by the five university hospitals during the study period. A few central hospitals have also organized physician staffed rapid response cars to support the local EMS.
Emergency calls are all made to a national emergency number 112 (healthcare, fire, police & social services). The calls are processed by Emergency Response Centre Operators (ERCO) in one of the six regional dispatch centers using a nationally unified, tiered dispatch structure assisting in the dispatch of units, with slight local variations. ERCOs are specially educated for the task but they are not healthcare providers. In addition to being alarmed by the dispatch centers, the HEMS units can also be requested by the EMS crews. A list of dispatch codes and those leading to HEMS activation can be seen in Additional File 1.
HEMS units are alerted to patients who are thought to benefit from early prehospital intensive care. Typical alarm criteria are Out-of-Hospital Cardiac Arrest (OHCA), major trauma and unconsciousness with an unknown origin. In the Finnish EMS system, HEMS units are not normally dispatched to conscious stroke patients, patients suffering from respiratory failure, and cardiovascular accidents, with the exception of the unit based in Lapland, due to the extremely sparse population and long distances in the area.
Five HEMS units are based at the university hospitals and one in Lapland, and their actual service areas encompassing 95% of the operations cover nearly the whole population of Finland (Fig. 1) [16 (link), 17 ]. The three southernmost units operate with Airbus H135 and the three other units with Airbus H145 helicopters. The primary task of the HEMS units is prehospital care, with rare interhospital transfers and search-and-rescues being decided upon in a case-by-case fashion.

The population density of Finland, location of HEMS bases and their actual service areas with 95% of the missions in 2017 [16 (link), 17 ]. The population density is shown as density (population per km2) per postal area. H = HEMS base, FH = FinnHEMS unit

The HEMS units operating out of the university hospitals are staffed by a physician, a HEMS Crew Member (HCM; either a paramedic or a firefighter according to local regulations) and a pilot, while the unit in Lapland has two advanced level flight paramedics and two pilots. Physicians in the HEMS units are mainly anesthesiologists with sub specialization in prehospital critical care whereas HCMs are specially trained in prehospital critical care as well as in aviation. The HEMS pilots have significant previous experience in either civilian or military helicopter operations.
The wide array of equipment and medications used in the HEMS units is not nationally standardized but locally governed by the hospital districts. All units are on-call 24/7/365 and are capable of flying under instrument flight rules and night-time flight operations using night vision goggles. Rapid response vehicles are available for the HEMS crews in every base for short-range missions or for when weather conditions don’t meet the HEMS minima for airborne operations.
Saviluoto A., Björkman J., Olkinuora A., Virkkunen I., Kirves H., Setälä P., Pulkkinen I., Laukkanen-Nevala P., Raatiniemi L., Jäntti H., Iirola T, & Nurmi J. (2020). The first seven years of nationally organized helicopter emergency medical services in Finland – the data from quality registry. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 28, 46.
Publication 2020
Accidents Anesthesiologist Cardiovascular System Cerebrovascular Accident Conditioning, Psychology Consciousness Critical Care Crow Dark Adaptation Emergencies Health Personnel Hemorrhage Intensive Care Military Personnel Minimally Invasive Surgical Procedures Out-of-Hospital Cardiac Arrest Paramedical Personnel Patients Pharmaceutical Preparations Physicians Respiratory Failure Vision Wounds and Injuries
3
RNA Backbone Repair via FCCD
Cited 12 times
Possible discontinuities in the backbone (resulting e.g. from an imperfect match of fragment ends to the flanking regions of the template), are repaired using the Full Cyclic Coordinate Descent (FCCD) algorithm that connects two ends with a minimal number of operations (41 (link)). ModeRNA rebuilds coordinates of the RNA backbone atoms between two residues, aiming to restore the following native-like features, ordered according to the priority (i) acceptable bond lengths, (ii) absence of interatomic clashes, (iii) acceptable bond angles, (iv) acceptable torsion angles. Acceptable values of bond lengths and angles have been taken from a statistical analysis of structures in our fragment library. Acceptable torsion angles were directly taken from Richardson et al. (39 (link)). To avoid clashes, 42 RNA suites defined by Richardson et al. (39 (link)) are tried one after another as starting conformations, until a clash-free loop closure is found. Subsequently, the positions of the most flexible P and O5′ atoms are optimized by a simple stochastic search algorithm trying to satisfy angle and dihedral constraints. For generating coordinates at various stages of the procedure, the NeRF algorithm used in ROSETTA (42 (link)) has been implemented. In case the entire procedure fails to close the backbone, details about the kind of distortion for the residues flanking the problematic site are reported.
Rother M., Rother K., Puton T, & Bujnicki J.M. (2011). ModeRNA: a tool for comparative modeling of RNA 3D structure. Nucleic Acids Research, 39(10), 4007-4022.
Publication 2011
DNA Library Minimally Invasive Surgical Procedures Vertebral Column
4
Andexanet Alfa for Acute Major Bleeding
Cited 8 times
Patients were enrolled at 63 centers in North America and Europe. Patients were eligible if they were at least 18 years of age, presented with acute major bleeding, and had received within 18 hours one of the following: apixaban, rivaroxaban, or edoxaban at any dose or enoxaparin at a dose of at least 1 mg per kilogram of body weight per day. Acute major bleeding was defined as bleeding having one or more of the following features: potentially life-threatening bleeding with signs or symptoms of hemodynamic compromise (e.g., severe hypotension, poor skin perfusion, mental confusion, or low cardiac output that could not otherwise be explained); bleeding associated with a decrease in the hemoglobin level of at least 2 g per deciliter (or a hemoglobin level of ≤8 g per deciliter if no baseline hemoglobin level was available); or bleeding in a critical area or organ (e.g., retroperitoneal, intraarticular, pericardial, epidural, or intracranial bleeding or intramuscular bleeding with compartment syndrome). Written informed consent was obtained from all the patients, whether directly from the patient, by proxy consent from a legally authorized representative, or by emergency consent (as described in the Supplementary Appendix, available at NEJM.org).
Patients were enrolled from April 2015 through May 2018. From July 2016 through August 2017, only patients with intracranial hemorrhage were enrolled to enrich the study with these patients. After August 2017, patients with all types of bleeding except visible, musculoskeletal, or intraarticular bleeding were enrolled. Substantive amendments to the enrollment criteria during the trial are presented in the Supplementary Appendix.
Key exclusion criteria were planned surgery within 12 hours after andexanet treatment (with the exception of minimally invasive operations or procedures); intracranial hemorrhage in a patient with a score of less than 7 on the Glasgow Coma Scale (scores range from 15 [normal] to 3 [deep coma]) or an estimated hematoma volume of more than 60 cc; expected survival of less than 1 month; the occurrence of a thrombotic event within 2 weeks before enrollment; or use of any of the following agents within the previous 7 days: vitamin K antagonist, dabigatran, prothrombin complex concentrate, recombinant factor VIIa, whole blood, or plasma.
Connolly S.J., Crowther M., Eikelboom J.W., Gibson C.M., Curnutte J.T., Lawrence J.H., Yue P., Bronson M.D., Lu G., Conley P.B., Verhamme P., Schmidt J., Middeldorp S., Cohen A.T., Beyer-Westendorf J., Albaladejo P., Lopez-Sendon J., Demchuk A.M., Pallin D.J., Concha M., Goodman S., Leeds J., Souza S., Siegal D.M., Zotova E., Meeks B., Ahmad S., Nakamya J, & Milling TJ J.r. (2019). Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors. The New England journal of medicine, 380(14), 1326-1335.
Publication 2019
andexanet apixaban BLOOD Body Weight Comatose Compartment Syndromes Dabigatran edoxaban Emergencies Enoxaparin Factor IX Complex Hematoma Hemodynamics Hemoglobin Hemoglobin A Intracranial Hemorrhage Minimally Invasive Surgical Procedures Operative Surgical Procedures Patients Perfusion Pericardium Plasma recombinant FVIIa Retroperitoneal Space Rivaroxaban Skin Vitamin K
5
Evaluating Interdisciplinary Research Trends
Cited 6 times
There are various indicators used in the study to better demonstrate distribution of the literature. The total local citation score (TLCS) and the total global citation score (TGCS) were calculated in this study, which have been the key indicators capable of evaluating the relevance of each research paper in our sample [16 ]. TLCS refers to the number of times that a set of papers included in a collection has been cited by other papers within the same collection, whereas TGCS refers to the number of times that a set of papers included in a collection has been cited in the WoSCC [17 (link)]. In addition, the average global citation score (AGCS) is the mean value of TGCS. However, it should be noted that TLCS presents the important papers in a chosen research area, whereas TGCS mainly displays the effects of the papers related to a chosen research area on the papers in the WoSCC [18 (link)]. Distribution of the literature was presented using the HistCite tool, which is an analysis and visualization software that helps us to obtain information at the country and institution level [19 ]. Meanwhile, we divided the 21 years into 4 periods of time to exam the distribution at the country level.
Furthermore, interdisciplinarity and cross-disciplinarity have been buzzwords for the last few years, which are used to describe contributions from and collaborations among several or more disciplines. Interdisciplinary means that the content of research is not only a method or ability in a field but a field that involves more [20 (link)]. Through interdisciplinary research, we can more comprehensively understand the research content of a field. Interdisciplinary inevitably exists between disciplines, indicating that the scope involved in a certain field is constantly expanding [21 (link)]. Meanwhile, research areas constitute a subject categorization scheme that is shared by all Web of Science product databases. The literature indexed by WoSCC is assigned to at least 1 subject category, which is mapped to 1 research area [22 ]. VOSviewer—a software tool developed by Nees Jan van Eck and Ludo Waltman at Leiden University's Centre for Science and Technology Studies [23 (link)]—was employed to visualize the interdisciplinary collaboration on the basis of subject categorization of publication [24 (link)]. Each node represents a discipline, whereas the connection between nodes represents collaborations between disciplines. In addition, nodes with a close connection are assigned the same color to form their respective clusters. Furthermore, a co-occurrence matrix was generated by using the Bibliographic Item Co-occurrence Mining System (BICOMS) [25 (link)] to calculate the centrality, which includes degree centrality, closeness centrality, and betweenness centrality by using Ucinet6.6 [26 (link)]. Degree centrality is simply the number of tie of a given type that a node has; closeness is an inverse measure of centrality in the sense that large numbers indicate that a node is highly peripheral, whereas small numbers indicate that a node is more central; betweenness centrality is a measure of how often a given node falls along the shortest path between 2 other nodes [27 ]. Moreover, we analyzed the centrality in the different periods of time based on the top 5 centralities over the period from 1997 to 2017.
In addition, we used Cortext to visualize the evolution of individual disciplines and interdisciplinary clusters. The tubes layout represents the transformation of cluster of discipline over time [28 (link)-30 ]. The width of tubes represents the number of records in which they appear in the same cluster. Darker tubes mean more disciplines are shared between 2 consecutive time periods.
Finally, 3 stages were completed, as follows, regarding the analysis of research hotspots. First, BICOMS was employed to calculate the frequency of keywords. Subsequently, a total of 13,706 keywords were obtained and merged based on the following 4 criteria [31 (link)]: (1) merging some keywords into corresponding Medical Subject Headings terms using PubMed (eg, “gynaecology” and “lymphadenectomy” were merged into “gynecology” and “lymph node excision,” respectively); (2) unifying the uppercase and lowercase of some keywords (eg, “Laparoscopy” and “Bladder cancer” were changed to “laparoscopy” and “bladder cancer,” respectively); (3) standardizing the singular and plural of keywords (eg, “child” and “pediatric” were changed to “children” and “pediatrics,” respectively); and (4) merging some synonym keywords (eg, “minimal invasive surgery” and “MIS” were replaced by “minimally invasive surgery”). After merging, 90 keywords with frequencies not less than 40 were obtained.
Second, we used BICOMS to generate the 88×88 co-occurrence matrix of keywords with a frequency not less than 40. It is worth noting that we removed robotic surgery and surgical robot because they are our research object. Then, a social network map was drawn with respect to these 88 keywords by Ucinet6.6 and VOSviewer [26 (link),32 ,33 (link)], which intuitively reflects the relationship between keywords of high frequency. The relative size of nodes is proportional to the frequency of keywords, whereas the relative width of lines is proportional to the correlation between keywords [34 (link)].
Third, we detected the burst strength of the cleaned keywords and drew a temporal bar graph for high-burst strength keywords. Burst strength depicts the intensity of the burst, that is, how great the change is in the word frequency that triggered the burst. Kleinberg burst detection algorithm [35 (link)] can recognize the sudden increase of word frequency over time and detect the burst of keyword popularity effectively. We chose Science of Science (Sci2) [36 ], which can implement this algorithm to find out the burst terms in the processed data and calculate the burst strength. Finally, 48 keywords with a burst strength of not less than 4 were obtained. However, these keywords may only be core keywords to a certain extent. Further screening by word frequency can improve the quality of core keywords. The higher the number of keyword frequency, the more likely it is to become a hot topic in future. Then we drew a temporal visualization map of 26 keywords with a frequency no less than 40 and burst strength more than 4 by Sci2 [37 (link)]. Each keyword has its own starting and ending time, and the area of each bar reflects its burst strength.
Shen L., Wang S., Dai W, & Zhang Z. (2019). Detecting the Interdisciplinary Nature and Topic Hotspots of Robotics in Surgery: Social Network Analysis and Bibliometric Study. Journal of Medical Internet Research, 21(3), e12625.
Publication 2019
Biological Evolution Bladder Neoplasm Child Darkness Laparoscopy Lymph Node Excision Maritally Unattached Minimally Invasive Surgical Procedures Operative Surgical Procedures Robotic Surgical Procedures

Most recents protocols related to «Minimally Invasive Surgical Procedures»

1
Minimally Invasive Magnetic Hyperthermia Instruments
With the idea of an MFH technique limited only to small tumor sizes, a special instrument was needed to deliver the heat in a minimally invasive manner. One potential end use of the LIH is during a laparoscopic procedure, a minimal invasive surgery where the surgeon inserts multiple tube-like instruments (with different functions) through small incisions in the patient’s body [53 –56 (link)]. This instrument was designed with a tube-like structure, considering current laparoscopic instrument designs, and its performance is mainly limited by the magnetic generator parameters and the electrical current flowing through it. The TRIH was designed for prostate cancer malignancies. This instrument could be used to reach the prostate transrectally or to access the prostate by placing it in contact with the perineum. A normal prostate has a volume of approximately 25 cm3. Nevertheless, in cases of benign prostate hyperplasia (BPH) or prostate cancer, the prostate volume can increase to over 30 cm3. This was the rationale behind designing this coil larger than the one in the LIH.
The enclosures for each instrument were designed to have a medical device appearance, while also providing a means to maintain the internal temperature of the coil below 155 °C to avoid damage. Both embodiments were designed using NX software (Siemens, Plano, TX, USA) and were partially constructed by a Zortrax Inkspire 3D printer (Zortrax SA, Olsztyn, Poland) with epoxy-based resin from the same company. The constructs can regulate the coil temperature by circulating water (20 °C–25 °C) throughout the instrument similar as inside MFH coils [57 (link)]. The materials for the LIH design and its measurements were selected considering the dimensions of current laparoscopic instruments. A polycarbonate tubing (⌀inner = 12.7 mm × ⌀outer = 15.9 mm × 1.6 mm wall) (Small Parts Inc., Logansport, IN, USA) connected the 3D printed parts (handle and tip). The handle included the water inlet and outlets, as well as a nylon wet-location multi-cord grip (McMaster-Carr, Elmhurst, IL, USA) for the 6 AWG Type 2 Litz wires that connect directly to the circuit. The tip was where the coil was placed and served as a connection point for the Masterflex® 25 L/S® inner tubing (Cole-Palmer, Vernon Hills, IL, USA). This ensures that the water flows right into the coil before exiting the instrument. A cap at the tip ensured fast replacement of the coil if a problem was encountered. The overall length of the LIH was approximately 23 cm (see figure 3(a)).
The TRIH design was similar in the parts used, but different in shape. In this case, a tygon flexible tubing (⌀inner = 25.4 mm × ⌀outer = 31.8 mm × 3.2 mm wall) (McMaster-Carr, Elmhurst, IL, USA) connected the 3D printed parts (handle and tip). Similar to the LIH, the handle included the water inlet and outlets, as well as the nylon wet-location multi-cord grip for the 6 AWG Type 2 Litz wires that connect directly to the circuit. The tip in this case also enclosed the coil and served as a connection point for the 25 L/S® inner tubing. This part had a 4-jet nozzle for improved heat removal of this larger coil. This design also had a cap for fast replacement of the coil if a problem was encountered. Because of the 3D printed enclosure, the instrument itself is slightly larger than what we aim to use in the future. However, this does not affect its performance, as the coil has the exact dimensions we designed for. The overall length of the TRIH was approximately 25 cm (see figure 3(b)).
Castro-Torres J.L., Méndez J., Torres-Lugo M, & Juan E. (2023). Development of handheld induction heaters for magnetic fluid hyperthermia applications and in-vitro evaluation on ovarian and prostate cancer cell lines. Biomedical Physics & Engineering Express, 9(3), 035010.
Publication 2023
Benign Prostatic Hyperplasia Cone-Rod Dystrophy 2 Electricity Epoxy Resins Grasp Human Body Laparoscopy Malignant Neoplasms Medical Devices Minimally Invasive Surgical Procedures Neoplasms nylon 6 Nylons Patients Perineum polycarbonate Prostate Prostate Cancer Surgeons
2
Surgical Procedures Database Analysis
Categories of common surgical purposes and procedures were set across the fields and included transplantation surgery, trauma surgery, surgical oncology (operations of malignant disease), endoscopic and minimum invasive surgery, including robot-assisted surgery, and the number of corresponding programs were counted. As an example of advanced medical technologies, mediastinoscopic radical esophagectomy for esophageal cancer [5 (link)–7 (link)], transanal minimally invasive surgery (TAMIS) and transanal total mesorectal excision (TaTME) for rectal cancer [8 (link), 9 (link)], laparoscopic pancreaticoduodenectomy (Lap-PD) for pancreatic lesions [10 (link)], and minimally invasive cardiac surgery (MICS) for cardiovascular lesions [11 (link)] were selected, and their numbers were counted.
Shichinohe T., Date H., Hatano E., Kobayashi E., Hiramatsu M., Hirano S., Izawa Y, & Shirakawa Y. (2023). Cadaver surgical training and research using donated cadavers in the field of surgery in Japan: an overview of reports from 2012 to 2021. Surgery Today.
Publication 2023
Cardiovascular System Endoscopy Esophageal Cancer Esophagectomy Heart Laparoscopy Malignant Neoplasms Mediastinoscopy Minimally Invasive Surgical Procedures Operative Surgical Procedures Pancreas Pancreaticoduodenectomy Proctectomy Robotic Surgical Procedures Transanal Minimally Invasive Surgery Transplantation Wounds and Injuries
3
Minimally Invasive Spinal Metastasis Treatment
Six patients were diagnosed with malignant tumors and spinal metastases between May and August of 2021. There were five men and one woman with an average age of 59 years (range 50–71 years) and an average Karnofsky Performance Scale (KPS) score of 75 (range 70–80). All patients had symptoms of mechanical pain, nerve root, or/and spinal cord compression. Each patient signed informed consent and underwent robot and working tube-assisted ICS of spinal metastases. The robot was manufactured by Shanghai Jiao Information Technology Development Co., Ltd., and the catheter was manufactured by Medtronic, Inc. All patients had a limited life expectancy, with a mean revised Tokuhashi score of 8.8 (range 7–11). Table 1 provides a summary of the preceding key statistics. Before surgery, the patients underwent anteroposterior and lateral radiographs, computed tomography (CT), and magnetic resonance imaging (MRI) examination of the segment with the lesion and two to three adjacent segments. The average spine instability neoplastic score (SINS) was 10.2 points (range 8–13 points) according to the CT image. MRI demonstrated lesions were all located in the lower thoracic spine or lumbar spine. The lesions involved unilateral articular joints and led to unilateral nerve root or/and spinal cord compression. CT and MRI images are depicted in Figure 1. The responsible lesion segment involves a part of the side of the vertebral body and yet does not exceed the midline of the vertebral body. The patients with spinal metastasis from a malignant tumor required surgical intervention, but their physical condition was generally poor, and the minimally invasive surgical treatment plan was determined through multidisciplinary consultation.
Zhou S., Li B., Wang P., Xu M., Zhao J., Duan S., Zhu Z., Xu W, & Xiao J. (2023). Robot and working tube-assisted invasion-controlled surgery for spinal metastases. Frontiers in Surgery, 10, 1041562.
Publication 2023
Catheters Joints Malignant Neoplasms Minimally Invasive Surgical Procedures Neoplasm Metastasis Nervousness Operative Surgical Procedures Pain Parts, Body Patients Physical Examination Plant Roots Spinal Cord Compressions Spinal Cord Neoplasms Vertebra Vertebrae, Lumbar Vertebral Body Vertebral Column Woman X-Ray Computed Tomography X-Rays, Diagnostic
4
Minimally Invasive Breast Mass Excision
All minimally invasive surgical procedures were conducted using a vacuum-assisted Mammotome biopsy system (Devicor Medical Products, Inc.) with the following components: 8G Mammotome rotary cutter, control handle, vacuum suction pump and associated software (Mammotome EX SCMSW5). While undergoing routine sterilization, the patient was placed in a supine or semi-lateral position with their ipsilateral arm lifted up and then draped with a surgical towel. A moderate anesthetic (local anesthesia, 1% lidocaine ≤200 mg.) was administered subcutaneously and underneath the posterior breast space in the surgical area. A ~3-mm incision was made in the predetermined location, which allowed for the proper insertion of the 8G Mammotome needle. The needle was placed underneath the deep surface of the breast mass by US guidance at an appropriate angle so that the breast mass was just inside the groove of the needle (Fig. 1). Repeated rotary cutting was performed to remove the aspirated lesion tissue until no residual lesions were detected in the US images. After completion of the resection, hemostasis was performed in the surgical area to stop bleeding. Compression bandages were applied to all patients for 72 h following the procedure.
US BI-RADS classification. Breast mass classification was based on the latest edition of the US BI-RADS recommendations of the ACR (8 ). Two physicians with >10 years of breast US experience determined the US BI-RADS classification. If the analysis results were inconsistent, the two physicians discussed the results together until a consensus was reached. According to the US BI-RADS management recommendations, category 3 lesions should have a short (6-month) follow-up interval or continued surveillance, while category 4 lesions require biopsy for tissue diagnosis. As there is a marked difference in the treatment of category 3 and 4 lesions by clinicians, category 3 lesions were defined as benign and lesions of category 4 and above were defined as malignant in the present study.
Wang H., Wang Q., Zhang Y, & Peng Y. (2023). Value of ultrasound BI‑RADS classification in preoperative evaluation of the ultrasound‑guided Mammotome‑assisted minimally invasive resection of breast masses: A retrospective analysis. Experimental and Therapeutic Medicine, 25(4), 143.
Publication 2023
Anesthetics Biopsy Breast Compression Bandages Diagnosis Hemostasis Lidocaine Local Anesthesia Minimally Invasive Surgical Procedures Needles Operative Surgical Procedures Patients Physicians RRAD protein, human Sterilization Suction Drainage Tissues Vacuum
5
Diagnostic Efficacy of US BI-RADS in Breast Masses
SPSS19.0 (IBM Corp.) statistical analysis software was used to analyze the diagnostic efficacy of US BI-RADS classification in breast masses that underwent minimally invasive resection using the Mammotome system. To detect statistical differences in lesion characteristics, χ2-test was used for shape while Fisher's exact test was used for other characteristics. The specificity, sensitivity, accuracy, positive predictive value and negative predictive value were calculated by comparison with pathology results. The receiver operating characteristic (ROC) curve for the US BI-RADS classification in the diagnosis of breast masses subjected to minimally invasive surgery was constructed, and the area under curve (AUC) was calculated.
Wang H., Wang Q., Zhang Y, & Peng Y. (2023). Value of ultrasound BI‑RADS classification in preoperative evaluation of the ultrasound‑guided Mammotome‑assisted minimally invasive resection of breast masses: A retrospective analysis. Experimental and Therapeutic Medicine, 25(4), 143.
Publication 2023
Breast Diagnosis Hypersensitivity Minimally Invasive Surgical Procedures RRAD protein, human

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Collagenase 4 by Merck Group
Sourced in United States, Germany, United Kingdom, France, China, Sao Tome and Principe, Israel, Canada, Macao, Italy, Australia, Japan, Switzerland, Senegal
Collagenase IV is a purified enzyme used to dissociate and isolate cells from various tissue types. It is effective in breaking down collagen, a major structural component of the extracellular matrix.
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Franz cell system by Teledyne
Sourced in United States
The Franz Cell system is a lab equipment product designed for the study of membrane permeability. It consists of two chambers separated by a membrane, allowing the measurement of the diffusion or transport of substances across the membrane. The system enables researchers to assess the permeability characteristics of various materials or compounds.

More about "Minimally Invasive Surgical Procedures"

Minimally Invasive Surgical Procedures (MISP) are a diverse range of surgical techniques that aim to minimize tissue damage and accelerate patient recovery times.
These procedures utilize small incisions, specialized instruments, and advanced imaging technologies to perform complex operations with enhanced precision and reduced invasiveness.
By leveraging innovative approaches, surgeons can target specific areas of the body with minimal disruption to surrounding structures, leading to improved patient outcomes and faster healing.
This MeSH term encompasses a variety of minimally invasive techniques, such as laparoscopic, arthroscopic, and endovascular procedures, that have transformed modern surgery and enhanced the quality of patient care.
Synonyms for MISP include keyhole surgery, minimally invasive surgery (MIS), and minimally invasive interventions.
Related terms include robotic-assisted surgery, computer-assisted surgery, and image-guided surgery.
The advancements in MISP have been facilitated by the development of specialized instruments, such as the Da Vinci Surgical System, and the use of technologies like Suprarenin (a vasoconstrictor used to reduce bleeding) and Toradol (a nonsteroidal anti-inflammatory drug) to optimize surgical outcomes.
Additionally, the utilization of imaging modalities, such as the CS 9000 3D system, has enabled surgeons to precisely target and access areas of the body with minimal disruption.
The ongoing research and innovation in MISP have led to the emergence of new techniques, such as endovascular procedures, which involve the use of catheters and other specialized tools to perform minimally invasive interventions within the body's blood vessels.
The use of Collagenase IV and the Franz Cell system have also been instrumental in the development of new MISP approaches.
To further enhance the precision and safety of MISP, researchers have been studying the use of C57BL/6J mice as model organisms, as well as the application of Penicillin/streptomycin to prevent postsurgical infections.
These advancements, coupled with the continued evolution of MISP techniques, have the potential to revolutionize the field of surgery and improve patient outcomes across a wide range of medical specialties.