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Pulmonary Surgical Procedures

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Most cited protocols related to «Pulmonary Surgical Procedures»

1
Comprehensive Lung Cancer Transcriptome Analysis
Cited 29 times
A total of 66 samples were used for microarray analysis, including paired adjacent normal-tumor samples from 27 patients underwent surgery for lung cancer at the Taipei Veterans General Hospital, two tissue mixtures from the Taichung Veterans General Hospital (one was adjacent normal lung mixtures and the other was lung adenocarcinoma mixtures), two commercial human normal lung tissues (Clontech (Catalog No. 636524) and Stratagene (Catalog No. 735020)), one immortalized, nontumorigenic human bronchial epithelial cell line (NL-20 (ATCC® No. CRL-2503™)) and 7 lung cancer cell lines (A-549 (ATCC® No. CCL-185™), NCI-H1299 (ATCC® No. CRL-5803™), NCI-H661 (ATCC® No. HTB-183™), CL1-0 [33 (link)], CL1-1 [33 (link)], CL1–5 [33 (link)], and CL1–5-F4 [34 (link)]).
Su L.J., Chang C.W., Wu Y.C., Chen K.C., Lin C.J., Liang S.C., Lin C.H., Whang-Peng J., Hsu S.L., Chen C.H, & Huang C.Y. (2007). Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. BMC Genomics, 8, 140.
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Publication 2007
Adenocarcinoma of Lung Bronchi Cell Lines Homo sapiens Lung Lung Cancer Malignant Neoplasms Microarray Analysis Neoplasms Operative Surgical Procedures Patients Pulmonary Surgical Procedures Tissues
2
Transcriptomic Profiling of Idiopathic Pulmonary Fibrosis
Cited 14 times
Specimens were obtained from the peripheral area of the lower lobe of each lung as soon as the first recipient lung was taken out, snap frozen in liquid nitrogen, and stored at − 80 °C. RNA was extracted and hybridized to the Human Gene 1.0 set array (Affymetrix) from explanted lungs (2001–2008) in 22 patients with clinical diagnosis of sporadic IPF, entirely typical UIP HRCT pattern [16 (link)] and definite histologic UIP pattern; 10 subjects with clinical diagnosis of idiopathic NSIP and definite histologic pattern of fibrotic NSIP; and 11 normal lung samples (age 52 ± 18 years, 4 females) obtained from the region of normal tissue flanking lung cancer resections in ILD-free patients. Histopathologic diagnoses were based on whole explanted lungs. IPF cases with atypical radiographic features for UIP, and patients with other types of ILD, connective tissue disease or concomitant emphysema were excluded. A separate set of patients who underwent surgical lung biopsies at London Health Science Centre (Western University) (2005–2015) were identified and representative blocks were used for immunohistochemistry (IHC). This set included 23 cases with definite IPF/UIP and 13 with definite NSIP.
The study was approved by the Human Tissue Committees and Research Ethics Boards of the University Health Network (protocol n.11–0932) and Western University (n.105214).
Cecchini M.J., Hosein K., Howlett C.J., Joseph M, & Mura M. (2018). Comprehensive gene expression profiling identifies distinct and overlapping transcriptional profiles in non-specific interstitial pneumonia and idiopathic pulmonary fibrosis. Respiratory Research, 19, 153.
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Publication 2018
Biopsy Connective Tissue Diseases Diagnosis Females Fibrosis Freezing Homo sapiens Immunohistochemistry Lung Lung Cancer Nitrogen Patients Pulmonary Emphysema Pulmonary Surgical Procedures Tissues X-Rays, Diagnostic
3
COPD Comorbidities Observational Cohort
Cited 12 times
Keio University and affiliated hospitals have established an observational COPD cohort designed to prospectively investigate the management of COPD comorbidities. A total of 572 subjects were enrolled between April 2010 and December 2012, including patients who had been diagnosed as having COPD and at risk for COPD (non-COPD) by pulmonary physicians. Inclusion criteria consisted of (1) age≧40 years old, (2) forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) < 0.7, (3) presence of emphysematous changes on chest computed tomography (CT) scans, and (4) chronic respiratory symptoms with significant smoking history (≧30 pack-years). Pulmonary function tests and chest CT scan were performed in all participants, and the COPD group fulfilled the criteria (1) and (2), while the non-COPD group met the criteria (1) and either (3) or (4) without airflow limitation (FEV1/FVC≧0.7). Excluded were patients who had a history of lung resection surgery or serious complications such as unstable cardiovascular or cerebral diseases and malignant tumors under treatment. For the purpose of this study, only subjects with complete data available for comorbidities (n = 403) were enrolled. All patients were clinically stable and without exacerbations for at least one month prior to recruitment. The protocol was approved by the ethics committees of Keio University and the affiliated hospitals, and written, informed consent was obtained from each patient.
Miyazaki M., Nakamura H., Chubachi S., Sasaki M., Haraguchi M., Yoshida S., Tsuduki K., Shirahata T., Takahashi S., Minematsu N., Koh H., Nakamura M., Sakamaki F., Terashima T., Sayama K., Jones P.W., Asano K, & Betsuyaku T. (2014). Analysis of comorbid factors that increase the COPD assessment test scores. Respiratory Research, 15(1), 13.
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Publication 2014
Cardiovascular System Chest Chronic Obstructive Airway Disease Ethics Committees Forced Vital Capacity Lung Malignant Neoplasms Patients Physicians Pulmonary Emphysema Pulmonary Surgical Procedures Radionuclide Imaging Signs and Symptoms, Respiratory Tests, Pulmonary Function Volumes, Forced Expiratory X-Ray Computed Tomography
4
IPF-PRO Registry: Eligibility and Enrollment
Cited 8 times
To be eligible to participate in the registry, patients must be aged ≥40 years with a diagnosis of IPF confirmed at a tertiary pulmonary care centre according to current international guidelines within 3 months of the registry enrolment date. At patient enrolment, each site investigator will complete an investigator assessment form recording the diagnostic category most supported by the cumulative clinical data (definite IPF, probable IPF or possible IPF according to American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association definitions based on High-resolution computed tomography patterns and surgical lung biopsy results1 (link)). Patients must be able to read and write in English and provide written informed consent.
Exclusion criteria include malignancy, other than skin cancer, within the past 5 years; being on a lung transplant waiting list or participating in a randomised clinical trial at the time of enrolment. Patients enrolled in a non-interventional registry are eligible for inclusion, and patients may enter a randomised clinical trial after enrolment in the IPF-PRO registry.
Physicians at the enrolling sites will be instructed to approach every eligible patient receiving care at their clinic about participation in the registry and to document reasons for non-participation. As IPF-PRO is a non-interventional registry, enrolled patients will receive usual care for IPF as defined by the treating physician.
O'Brien E.C., Durheim M.T., Gamerman V., Garfinkel S., Anstrom K.J., Palmer S.M, & Conoscenti C.S. (2016). Rationale for and design of the Idiopathic Pulmonary Fibrosis–PRospective Outcomes (IPF-PRO) registry. BMJ Open Respiratory Research, 3(1), e000108.
Publication 2016
Biopsy Cancer of Skin Diagnosis Europeans Japanese Lung Transplantation Malignant Neoplasms Patients Physicians Pulmonary Surgical Procedures Respiratory Rate Respiratory Therapy X-Ray Computed Tomography
5
Surgical Skill Evaluation of Trainees
Cited 8 times
We surveyed all operations, in which postgraduate year 3, 4, and 5 surgical trainees participated as the main surgeon or as the first assistant in Hiroshima City Asa Hospital, between January, 2007 and December, 2010. The surgical skills were evaluated using the global rating scale of the OSATS (Fig. 1).

The global rating scale used in the Objective Structured Assessment of Technical Skills (OSATS) [2 (link)], which we used to score the skills of each surgical trainee in performing or assisting in real operations. Full marks are 35 points on 7 items and 30 points on 6 items, respectively, as a surgeon and as an assistant (in the case of assistant, ‘Use of Assistant’ is excluded from the scoring)

Operations were classified according to whether the trainee was acting as the surgeon or the first assistant and were based on the level of difficulty of the surgical procedure. The surgical procedures were arbitrarily classified into three groups (Table 1). The scores of each trainee evaluated with the global rating scale were collected and studied in relation to each postgraduate year.

Example of the operation classification according to the degree of difficulty

Degree of difficultyOperations
LowThyroidectomy
Breast surgery
Bullectomy, VATS
Appendectomy (open or lap.)
Inguinal hernioplasty
IntermediateOpen lung surgery (such as lobectomy)
Open distal gastrectomy
Lap. local resection of the stomach
Open colectomy
Lap. cholecystectomy
Distal pancreatectomy
HighEsophagectomy
Lobectomy of lung (VATS)
Open or lap. total gastrectomy
Lap. distal gastrectomy
Lap. colectomy
Open or lap. proctectomy
Hepatectomy
Pancreatoduodenectomy
Evaluations were carried out by staff surgeons who participated in the operation in a supervisory role, rather than as a third-party evaluator who watched the operation or its video, because the main purpose of our method was to educate based on feedback, rather than to simply evaluate. To ensure objectivity of the evaluation, before starting this assessment system, all evaluators watched three videos of laparoscopic cholecystectomy being performed by three different trainees, and made a standard matching of the scores.
The scores of each trainee were analyzed as the median during each of nine terms, being the first term (from April to July), second term (from August to November), and third term (from December to March) in each postgraduate year. To examine the correlation between the postgraduate year and the surgical skill evaluated by the global rating scale, the scores in the second term of each year were statistically analyzed as follows: The Kruskal–Wallis test was used to compare the three groups and the Mann–Whitney U test was used to compare differences between two groups. Analyses were performed using the SPSS software application and p values <0.05 and 0.05/3 were considered to indicate significance.
Niitsu H., Hirabayashi N., Yoshimitsu M., Mimura T., Taomoto J., Sugiyama Y., Murakami S., Saeki S., Mukaida H, & Takiyama W. (2012). Using the Objective Structured Assessment of Technical Skills (OSATS) global rating scale to evaluate the skills of surgical trainees in the operating room. Surgery Today, 43(3), 271-275.
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Publication 2012
Cholecystectomy, Laparoscopic Groin Lung Operating Tables Operative Surgical Procedures Pulmonary Surgical Procedures Supervision Surgeons Teaching Thoracic Surgery, Video-Assisted

Most recents protocols related to «Pulmonary Surgical Procedures»

1
Primary CRC Radical Surgery Outcomes
A total of 394 patients with primary CRC, who underwent radical operation between 2013 and 2015 at Liaoning Cancer Hospital and Institute (Shenyang, Liaoning Province, People’s Republic of China) were included in this study. All patients were at stages I, II, or III according to the Union for International Cancer Control TNM classification system. Patients who died perioperatively or with secondary malignancy and those with distant metastases such as liver or lung before the operation were excluded. Histology specimens were evaluated by two senior pathologists, and the diagnosis of CRC with or without NED was confirmed in all patients. This study was approved by the local ethics committee of Liaoning Cancer Hospital and Institute.
Chen Y., Liang Y., Cao L., Dong X, & Sun D. (2023). Neuroendocrine differentiation: a risk fellow in colorectal cancer. World Journal of Surgical Oncology, 21, 89.
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Publication 2023
Diagnosis Ethics Committees, Clinical Liver Malignant Neoplasms Neoplasm Metastasis Pathologists Patients Pulmonary Surgical Procedures
2
Tele-delivered Exercise for Lung Transplant Patients

Protocol full text hidden due to copyright restrictions

Open the protocol to access the free full text link

Publication 2023
Blood Pressure Chronic Condition Disorders, Cognitive Eligibility Determination Grafts Hearing Heart Infantile Neuroaxonal Dystrophy Lung Lung Transplantation Medical Devices Operative Surgical Procedures Patient Discharge Patients Physical Examination Physicians Pulmonary Surgical Procedures Rehabilitation Transplant, Organ
3
Perioperative Factors in Lung Surgery Outcomes
We collected following variables, including: 1) basic demographics such as age, sex, history of smoking, body mass index (BMI), preoperative chemotherapy, history of lung surgery; 2) preoperative comorbidities containing hypertension, chronic obstructive pulmonary disease (COPD), asthma, diabetes, coronary heart disease, arrhythmia; 3) preoperative laboratory testing including Hemoglobin, serum albumin, Serum glucose; 4) preoperative pulmonary function including forced vital capacity rate of one second(FEV1/FVC), diffusion capacity for carbon monoxide of the lung(DLCO); 5) surgery related characteristics including surgery types, surgery extent, surgery sides, duration of surgery; 6) anesthesia related characteristics including ASA grade, anesthesia types, use of flurbiprofen axetil, use of colloid, allogenic blood transfusion, Input per unit of time (ml·kg-1·h-1). Smoking was defined as smoking index ≥ 400. Duration of surgery was defined as the time interval between skin incision and suture. Input per unit of time was equal to total input divided by duration of surgery and actual weight.
Jin F., Liu W., Qiao X., Shi J., Xin R, & Jia H.Q. (2023). Nomogram prediction model of postoperative pneumonia in patients with lung cancer: A retrospective cohort study. Frontiers in Oncology, 13, 1114302.
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Publication 2023
Anesthesia Asthma Blood Transfusion Cardiac Arrhythmia Chronic Obstructive Airway Disease Colloids Diabetes Mellitus Diffusion flurbiprofen axetil Glucose Heart Disease, Coronary Hemoglobin High Blood Pressures Index, Body Mass Lung Lung Capacities Monoxide, Carbon Operative Surgical Procedures Pharmacotherapy Pulmonary Surgical Procedures Serum Serum Albumin Skin Sutures
4
Isolation and Characterization of Human Lung Fibroblasts
Surgical lung biopsy tissue was obtained from consented patients under protocols approved by the Institutional Review Board of Weill Cornell Medical College and included macroscopically normal surgical waste tissue specimens. Unidentified waste tissue specimens were used for human lung fibroblast cultures. Lung fibroblasts were isolated from human lung tissue specimens. The human lung tissue was digested with type I collagenase solution (Thermo Fisher, Waltham, MA, United States 1%) and then spun down. Cell pellets were resuspended in DMEM/F12 (Corning, Corning, NY, United States) with 10% fetal bovine serum (Hyclone Laboratories, Logan, UT, United States) and 1% penicillin/streptomycin/amphotericin (Corning, Corning, NY, United States) and the cells were plated into T75 tissue culture flasks. Before treatments cells were left quiescent for 24 h. Treatments included exposure to MC-EXO (40 μg total protein), TGF-β (Peprotech, Cranbury, NJ, United States 10 ng/ml) with or without the TGF-βR1 inhibitor SB525334 (Selleck Chemicals, Houston, TX, United States 10 μM). Cells were pretreated with the inhibitor or vehicle [phosphate-buffered saline (PBS) or ethanol] 15 min before treatment with TGF-β and MC-EXO.
Savage A., Risquez C., Gomi K., Schreiner R., Borczuk A.C., Worgall S, & Silver R.B. (2023). The mast cell exosome-fibroblast connection: A novel pro-fibrotic pathway. Frontiers in Medicine, 10, 1139397.
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Publication 2023
Amphotericin Biopsy Cells Collagenase, Clostridium histolyticum Ethanol Ethics Committees, Research Fetal Bovine Serum Fibroblasts Homo sapiens Lung Operative Surgical Procedures Patients Pellets, Drug Penicillins Phosphates Proteins Pulmonary Surgical Procedures Saline Solution SB 525334 Streptomycin Tissues Transforming Growth Factor beta
5
Uniportal vs. Multiportal VATS Matching
Descriptive statistics were calculated and presented by groups, using median and interquartile range (IQR) for continuous variables and frequency and percentage for categorical variables. Continuous variables were compared between groups using Wilcoxon rank sum test and for categorical variables we used Chi-squared test or Fisher’s exact test if any cell count was 5 or less. Given the nonrandom treatment assignment and to minimize selection bias, we matched 1:1 uniportal patients and multiportal patients using propensity score matching methods. We performed a multivariate logistic model to calculate propensity scores for each patient accounting for the following covariates: age, sex, tumor location (upper or lower), Charlson Comorbidity Index, previous lung surgery, clinical tumor size (not pathologic), smoking status, BMI, and FEV1%. Standardized mean differences were assessed before and after matching. No differences were found after matching, when comparing demographics and baseline characteristics between the matched groups. We performed a post-match balance assessment and generated 2 groups with 156 patients in each cohort. Data was analyzed before and after propensity score matching and used SAS software version 9.4 (SAS Institute Inc., Cary, NC, USA). We considered P values less than 0.05 as statistically significant.
Diaz-Gutierrez I., Menier C.A., Savoie-White F.H., Doyle J.E., Wang Q., Andrade R.S, & Figueroa P.U. (2023). Uniportal vs. multiportal thoracoscopic segmentectomy: a north American study. Journal of Thoracic Disease, 15(2), 335-347.
Publication 2023
Neoplasms Neoplasms by Site Patients Pulmonary Surgical Procedures

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More about "Pulmonary Surgical Procedures"

Pulmonary surgical procedures, also known as thoracic or lung surgeries, are a critical aspect of respiratory healthcare.
These intricate operations involve the diagnosis, treatment, and management of various lung conditions, such as lung cancer, lung transplantation, and pulmonary nodules.
The success of these procedures is heavily dependent on the utilization of accurate and reproducible research protocols.
PubCompare.ai, an advanced AI-driven platform, offers a comprehensive solution to optimize pulmonary surgical procedures.
By leveraging a vast repository of literature, preprints, and patents, the platform empowers healthcare professionals to locate the best research protocols.
This ensures enhanced reproducibility and accuracy, ultimately elevating the quality and outcomes of pulmonary surgeries.
The platform's advanced comparison features enable users to confidently choose the right protocols and products for their specific needs.
This includes comparing the efficacy of different treatment methods, evaluating the performance of surgical instruments and devices, and exploring the latest advancements in lung tissue engineering and regenerative medicine.
Synonyms and related terms for pulmonary surgical procedures include thoracic surgery, lung surgery, respiratory surgery, and cardiothoracic surgery.
Abbreviations like VATS (video-assisted thoracic surgery) and RATS (robotic-assisted thoracic surgery) are also commonly used in this field.
Key subtopics within pulmonary surgical procedures include lung transplantation, lung volume reduction surgery, lobectomy, pneumonectomy, and the management of pulmonary nodules, pleural effusions, and interstitial lung diseases.
Advancements in these areas have been enhanced by the integration of technologies like HEPES, DMEM/F12, Y-27632, Ultraglutamine, and Primocin.
Additionally, the use of tools like the Human1M-Duo BeadChip array has facilitated the genetic profiling of lung tissues, enabling personalized treatment approaches and improved surgical outcomes.
By leveraging the insights gained from these technologies, healthcare professionals can optimize their pulmonary surgical procedures and deliver better patient care.