Ten percent buffered formalin was injected into wedge resection specimens using needle, or into segmentectomy, lobectomy, and pneumonectomy specimens from the bronchial stump soon after excision. After inflation of the lung, the specimen was soaked in 10% buffered formalin. All specimens were evaluated by three pathologists. Pathological tumor size was evaluated with hematoxylin and eosin staining (H&E) microscopically. We reviewed all pathological reports and restaged the cases after 2018 according to the 7th Edition of TNM in IASLC.
Ishizawa H., Matsuda Y., Ohno Y., Sakurai E., Ota A., Hattori H., Tsukamoto T., Matsunaga M., Kawai H., Suzuki Y., Nagano H., Negi T., Tochii D., Tochii S., Suda T, & Hoshikawa Y. (2023). Honeycomb lung is a major risk factor for preoperative radiological tumor size underestimation in patients with primary lung cancer. Journal of Thoracic Disease, 15(2), 516-528.