> Procedures > Therapeutic or Preventive Procedure > Splenectomy

Splenectomy

Q: What are some common reasons for undergoing a splenectomy?

Splenectomy, the surgical removal of the spleen, may be performed to treat a variety of conditions. The most common reasons include an enlarged or damaged spleen, certain blood disorders like immune thrombocytopenic purpura (ITP), and splenic injuries. Splenectomy can also be done as part of the treatment for some types of cancer affecting the spleen or blood.

Q: What are the different surgical approaches for a splenectomy?

Splenectomies can be performed through open surgery or minimally invasive techniques. Open splenectomy involves making a larger incision to access and remove the spleen, while laparoscopic splenectomy uses smaller incisions and specialized tools to perform the procedure in a less invasive manner. Laparoscopic splenectomy is often associated with a faster recovery time for patients.

Q: What are the potential risks and complications of a splenectomy?

One of the primary risks of splenectomy is an increased susceptibility to certain infections, as the spleen plays a crucial role in the body's immune system. Patients who undergo splenectomy may require lifelong antibiotic prophylaxis and close monitoring to manage this heightened infection risk. Other potential complications include bleeding, blood clots, and the risk of injury to surrounding organs during the procedure.

Q: How can PubCompare.ai assist with splenectomy research?

PubCompare.ai's AI-driven platform can help researchers optimize their splenectomy studies in several ways. First, it allows you to efficiently screen the literature and identify the most relevant protocols related to splenectomy. The platform's intelligent search and comparison tools can pinpoint critical insights, enabling you to choose the most effective protocols for your specific research goals. Secondly, PubCompare.ai's cutting-edge analysis can highlight key differences in protocol effectiveness, helping you select the best options for reproducibility and accuracy in your splenectomy research.

Q: Are there any new or emerging techniques in splenectomy procedures?

Reserach into splenectomy techniques is ongoing, with a focus on improving outcomes and reducing complications for patients. One area of innovation is the development of robotic-assisted splenectomy, which combines the precision of robotics with the minimally invasive approach of laparoscopic surgery. This technique may offer enhanced visualization and dexterity for the surgeon, potentially leading to faster recoveries and lower complication rates for patients.

Splenectomy is a surgical procedure involving the removal of the spleen, an organ located in the upper left part of the abdomen.
The spleen plays a crucial role in the body's immune system and blood filtration.
Splenectomy may be performed as a treatment for various conditions, such as an enlarged or damaged spleen, certain blood disorders, or splenic injuries.
The procedure can be done through open surgery or minimally invasive techniques like laparoscopic splenectomy.
Patients undergoing splenectomy may require lifelong antibotic prophylaxis and monitoring to manage the increased risk of infection due to the absence of the spleen.
Reserarch into optimal splenectomy protocols and techniques is ongoing to improve outcomes and reduce complications for patients.

Most cited protocols related to «Splenectomy»

Comprehensive Analysis of Surgical Complications at a University Hospital

Cited 33 times

Over the 6‑month period covering April 2010 to September 2010, all patients admitted to one of our patient wards at the Division of General Surgery, Department of Surgery, Medical University of Vienna were included in this study.
The Division of General Surgery in our university hospital consists of the following teams and specializations: colorectal surgery, hepatobiliary surgery, endocrine surgery, upper gastrointestinal (GI) surgery (esophageal and stomach surgery), bariatric surgery, breast surgery, and pancreatic surgery.
The patient data were extracted by reviewing all discharge letters from that period taken from the digital archives.
Overall, 517 patients were admitted over this period, some repeatedly, leading to a total of 817 admissions. These 517 patients underwent 463 operations. The complications of these operations were then rated according to the Clavien-Dindo classification (Table 1). For easier use, the suffix “d” for permanent disability was not drawn upon.Table 1

Clavien-Dindo classification

Grade	Definition
Grade I	Any deviation from the normal postoperative course without the need for pharmacological treatment, or surgical, endoscopic, and radiological interventions.Allowed therapeutic regimens are: drugs as antiemetics, antipyretics, analgetics, diuretics and electrolytes, and physiotherapy. This grade also includes wound infections opened at the bedside
Grade II	Requiring pharmacological treatment with drugs other than such allowed for grade I complications.Blood transfusions and total parenteral nutrition are also included
Grade III	Requiring surgical, endoscopic, or radiological intervention
Grade IIIa	Intervention not under general anesthesia
Grade IIIb	Intervention under general anesthesia
Grade IV	Life-threatening complication (including central nervous system complications) requiring IC/ICU management
Grade IVa	Single organ dysfunction (including dialysis)
Grade IVb	Multiorgan dysfunction
Grade V	Death of a patient

According to Dindo et al. [6 (link)]

IC intermediate care, ICU intensive care unit

The operations were sorted according to the complexity ranking (eight groups) in the accounting system of the Austrian Chamber of Physicians (Table 2; [8 ]).Table 2

Operation groups (complexity according to the Austrian Chamber of Physicians)

Operation group	Examples
I	Abscess incisions, secondary sutures, proctoscopy, skin biopsy
II	Excisions of atheromas, fibromas, lipomas, incisions of anal abscesses
III	Toe amputation, small lymph node extirpation, thoracic drainage, colonoscopy
IV	Tracheotomy, appendectomy, hernia operation, colostomy, gastrostomy, ERCP
V	Gastroenterostomy, interventions for recurrent hernia, Cimino fistula, radical varicose vein stripping
VI	Strumectomy, cholecystectomy, splenectomy, hemicolectomy, reduction mammoplasty
VII	Partial pancreatectomy, subtotal colectomy, subsegmental and large liver resections
VIII	Esophageal resection, open surgery of aortic aneurysms, organ transplantation

Bolliger M., Kroehnert J.A., Molineus F., Kandioler D., Schindl M, & Riss P. (2018). Experiences with the standardized classification of surgical complications (Clavien-Dindo) in general surgery patients. European Surgery, 50(6), 256-261.

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Publication 2018

Amputation Antiemetics Antipyretics Anus Aortic Aneurysm Appendectomy Atheroma Bariatric Surgery Blood Transfusion Central Nervous System Cholecystectomy Colectomy Colostomy Dialysis Disabled Persons Diuretics Drainage Electrolytes Endocrine Surgical Procedures Fibroma Fingers Fistula Gastrointestinal Surgical Procedure Gastrostomy Hemicolectomy Hepatectomy Hernia Intensive Care Lipoma Lymph Node Excision Operative Surgical Procedures Organ Transplantation Pancreas Pancreatectomy Parenteral Nutrition, Total Patient Discharge Patients Pharmaceutical Preparations Pharmacotherapy Physicians Proctoscopy Skin Splenectomy Stomach Surgical Endoscopy Surgical Wound Sutures Therapeutics Therapy, Physical Thoracic Surgical Procedures Treatment Protocols Upper Gastrointestinal Tract Varices Wound Infection X-Rays, Diagnostic

Standardized Approach to Genomic Blood-Cell Trait Analysis

Cited 11 times

Protocol full text hidden due to copyright restrictions

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Publication 2020

Anemia BLOOD Blood Cells Bone Marrow Transplantation Erythropoietin Europeans Gene Components Genetic Diversity Hematologic Neoplasms Kidney Failure, Chronic L Cells Liver Cirrhosis Pharmacotherapy Phenotype Phenotypic Sex Pregnant Women Splenectomy Syndrome, Myelodysplastic

Comprehensive Blood Cell Phenotype Analysis

Cited 10 times

When possible, we excluded samples with any of the following: pregnancy (when complete blood count (CBC) done), acute medical/surgical illness (when CBC done), blood cancer, leukemia, lymphoma, chemotherapy, myelodysplastic syndrome, bone marrow transplant, congenital or hereditary anemia (e.g., hemoglobinopathy such as sickle cell anemia or thalassemia), HIV, end-stage kidney disease, dialysis, EPO treatment, splenectomy, cirrhosis and those with any of the following extreme measurements: WBC count > 100^∗10⁹/L with > 5% immature cell or blasts, WBC > 200^∗10⁹/L, Hemoglobin > 20 g/dL, Hematocrit > 60%, Platelet > 1000^∗10⁹/L. For the WBC subtypes (e.g., basophils count) we used the relative count, i.e., the total WBC count multiplied by the proportion for each cell type (e.g., basophils percentage). Raw phenotypes were regressed on age, age-squared, sex, principal components and cohort specific covariates (e.g., study center, cohort, etc) if needed, WBC related traits were log₁₀ transformed before regression modeling. Residuals from the modeling were obtained and then inverse normalized for cohort level association analysis or GWAS. All cohorts followed the same exclusions and phenotype modeling except for UKBB and INTERVAL that had their procedure described elsewhere (Astle et al., 2016 (link)). The cohort level association analyses were then conducted using a linear mixed effects model in order to account for known or cryptic relatedness (e.g., BOLT-LMM (Loh et al., 2015 (link), 2018 (link)), EPACTS https://github.com/statgen/EPACTS and rvtests (Zhan et al., 2016 (link)) with the additive genetic model. Linear mixed effects models have been shown to effectively account for both population structure and inter-individual relatedness within the UK Biobank cohort, along with having increased discovery power over simple linear regression with principal components.

Vuckovic D., Bao E.L., Akbari P., Lareau C.A., Mousas A., Jiang T., Chen M.H., Raffield L.M., Tardaguila M., Huffman J.E., Ritchie S.C., Megy K., Ponstingl H., Penkett C.J., Albers P.K., Wigdor E.M., Sakaue S., Moscati A., Manansala R., Lo K.S., Qian H., Akiyama M., Bartz T.M., Ben-Shlomo Y., Beswick A., Bork-Jensen J., Bottinger E.P., Brody J.A., van Rooij F.J., Chitrala K.N., Wilson P.W., Choquet H., Danesh J., Di Angelantonio E., Dimou N., Ding J., Elliott P., Esko T., Evans M.K., Felix S.B., Floyd J.S., Broer L., Grarup N., Guo M.H., Guo Q., Greinacher A., Haessler J., Hansen T., Howson J.M., Huang W., Jorgenson E., Kacprowski T., Kähönen M., Kamatani Y., Kanai M., Karthikeyan S., Koskeridis F., Lange L.A., Lehtimäki T., Linneberg A., Liu Y., Lyytikäinen L.P., Manichaikul A., Matsuda K., Mohlke K.L., Mononen N., Murakami Y., Nadkarni G.N., Nikus K., Pankratz N., Pedersen O., Preuss M., Psaty B.M., Raitakari O.T., Rich S.S., Rodriguez B.A., Rosen J.D., Rotter J.I., Schubert P., Spracklen C.N., Surendran P., Tang H., Tardif J.C., Ghanbari M., Völker U., Völzke H., Watkins N.A., Weiss S., Cai N., Kundu K., Watt S.B., Walter K., Zonderman A.B., Cho K., Li Y., Loos R.J., Knight J.C., Georges M., Stegle O., Evangelou E., Okada Y., Roberts D.J., Inouye M., Johnson A.D., Auer P.L., Astle W.J., Reiner A.P., Butterworth A.S., Ouwehand W.H., Lettre G., Sankaran V.G, & Soranzo N. (2020). The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell, 182(5), 1214-1231.e11.

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Publication 2020

Anemia Anemia, Sickle Cell Basophils Blood Platelets Bone Marrow Transplantation Cells CFC1 protein, human Dialysis Genome-Wide Association Study Hematologic Neoplasms Hemoglobin Hemoglobinopathies Kidney Failure, Chronic Leukemia Liver Cirrhosis Lymphoma Pharmacotherapy Phenotype Pregnancy Splenectomy Syndrome, Myelodysplastic Thalassemia Volumes, Packed Erythrocyte

Splenectomy Procedure in Mice

Cited 10 times

Mice were anesthetized with ketamine and xylazine. The spleen was identified after a midline laparotomy incision and removed after appropriate blood vessel ligation. Sham animals underwent laparotomy without splenectomy.

Huston J.M., Ochani M., Rosas-Ballina M., Liao H., Ochani K., Pavlov V.A., Gallowitsch-Puerta M., Ashok M., Czura C.J., Foxwell B., Tracey K.J, & Ulloa L. (2006). Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. The Journal of Experimental Medicine, 203(7), 1623-1628.

Publication 2006

Animals Blood Vessel Ketamine Laparotomy Ligation Mice, House Spleen Splenectomy Xylazine

Epidemiology of Community-Acquired Pneumonia in China

Cited 8 times

Data were collected from 13 hospitals in Northern (Beijing), Central (Yantai, Qindao, Weifang, Zibo, Rizhao cities in Shandong Province) and Southern (Kunming City in Yunan Province) China. A listing of participating centres can be found in online supplementary appendix 1. All patients admitted to the 13 hospitals during 1 January 2014 through 31 December 2014 with the relevant disease codes of pneumonia or pulmonary infection in the WHO International Classification of Diseases 10th revision (online supplementary appendix 2) were eligible. Data on all eligible patients identified in screening were retrieved from the hospital information system in each centre. Trained physicians reviewed the medical case history and collected data on 786 variables for each patient. Chest radiographs and CT scans for each patient were reviewed by pulmonary physicians and radiologists in each centre. Two-level review process was performed for data collection and entry.
The CAP case definition includes (1) illness onset in the community (defined as community-acquired infection among those who have not been hospitalised during recent 28 days)10 (link); (2) chest radiograph or CT scan showing infiltrate or interstitial changes, with or without pleural effusion; (3) any one of pneumonia clinical manifestations: (1) recent cough, sputum or aggravation of respiratory symptoms, the emergence of purulent sputum, with or without chest pain; (2) fever (defined as axillary temperature≥37.3°C)11 (link) or hypothermia (axillary temperature<36°C); (3) signs of pulmonary consolidation and (or) moist crackles; or (4) white cell count >10×10⁹/L or <4×10⁹/L, with or without neutrophil predominance.
Patients were excluded if (1) age <14 years; (2) pneumonia onset ≥48 hours after admission; (3) lung infiltrate or interstitial changes that were interpreted as lung cancer, pulmonary tuberculosis, non-infectious interstitial lung diseases, pulmonary oedema, atelectasis, pulmonary embolism, pulmonary eosinophil infiltrate and pulmonary vasculitis; (4) immunocompromised status (including HIV(+), chemotherapy/radiotherapy within 6 months, immunosuppressive therapy, organ/bone marrow transplantation, splenectomy, haematological neoplasms); (5) readmission within 72 hours after discharge.

Chen L., Zhou F., Li H., Xing X., Han X., Wang Y., Zhang C., Suo L., Wang J., Yu G., Wang G., Yao X., Yu H., Wang L., Liu M., Xue C., Liu B., Zhu X., Li Y., Xiao Y., Cui X., Li L., Uyeki T.M., Wang C, & Cao B. (2018). Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey. BMJ Open, 8(2), e018709.

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Publication 2018

Atelectasis Axilla Bone Marrow Transplantation Chest Pain Community-Acquired Infections Cough Fever Hematologic Neoplasms Immunosuppression Infection Leukocyte Count Lung Lung Cancer Neutrophil Noncommunicable Diseases Patient Discharge Patients Pharmacotherapy Physicians Pleural Effusion Pneumonia Pneumonia, Interstitial Pulmonary Edema Pulmonary Embolism Pulmonary Eosinophilia Radiography, Thoracic Radiologist Radiotherapy Signs and Symptoms, Respiratory Splenectomy Sputum Tuberculosis, Pulmonary Vasculitis X-Ray Computed Tomography

Most recents protocols related to «Splenectomy»

Sensitivity Analysis of Surgical Outcomes

For the analysis of sensitivity, the mixed model analyses were replicated first excluding patients with pancreatic adenocarcinoma, then patients with a Clavien–Dindo complication score^{11 (link)} of IIIa or higher, and lastly patients who had undergone a spleen-preserving procedure. Because of the results of the latter, separate mixed model analyses were done comparing patients who had undergone splenectomy with those who had not.

Johansen K., Lindhoff Larsson A., Lundgren L., Gasslander T., Hjalmarsson C., Sandström P, & Björnsson B. (2023). Quality of life after open versus laparoscopic distal pancreatectomy: long-term results from a randomized clinical trial. BJS Open, 7(2), zrad002.

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Publication 2023

Adenocarcinoma Hypersensitivity Pancreas Patients Spleen Splenectomy

Optimal Splenectomy Procedure for Liver Dysfunction

Patients with liver dysfunction were given liver protection treatment, vitamin supplementation, and anemia correction before surgery, especially for Child–Pugh class C, which should be adjusted to class B. Open splenectomy was used in all cases. The splenic colonic and gastric splenic ligaments were separated, and the splenic artery was fully exposed and ligated under unambiguous vision. Next, the second- and third-grade branch vessels of the spleen were dissected and ligated one by one. After that, the splenic ligament was dissociated sharply, and the spleen was completely removed. For patients with pericardia varices, the esophageal branches, lateral branches, and inferior diaphragmatic branches about 5 cm in the lower esophagus were ligated and severed. Finally, drainage tubes were placed, followed by layer and layer suture. Postoperative anti-infection, liver protection and other support treatments were given.

Zheng Z., Yu Q., Peng H., Huang L., Zhang W., Shen Y., Feng H., Jing W, & Zhang Q. (2023). Nomogram-based prediction of portal vein system thrombosis formation after splenectomy in patients with hepatolenticular degeneration. Frontiers in Medicine, 10, 1103223.

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Publication 2023

Anemia Anti-Infective Agents Blood Vessel Child Colon Drainage Esophagus Ligaments Liver Operative Surgical Procedures Patients Pericardium Spleen Splenectomy Splenic Artery Stomach Sutures Varices Vision Vitamins

Preoperative Factors in Liver Surgery

The included demographic features were age, sex, and Child–Pugh classification (scores of 5–6, 7–9, and 10–15 for classes A, B, and C, respectively). Method of surgery, whether anatomic splenectomy was performed, BMI at admission: BMI = weight (kg)/height (m²), diabetes mellitus, hypertension, smoking history (one or more cigarettes daily for 6 months), duration of surgery, intraoperative bleeding and splenomegaly grade. Patients fasted for 8–12 h, and 5 mL of venous blood was extracted at 8 am before the procedure. Automatic hemacytometer (XN-9000, Sysmex Corporation, Japan) was used to detect the level of WBC, RBC, hemoglobin (HGB), and hematocrit (HCT) by counter method. Activated partial thromboplastin time (APTT), prothrombin time (PT), and fibrinogen (FIG) were determined using the coagulation method, and D-dimer was determined using immunoturbidimetry. Automatic biochemical analyzer (7600-010, Hitachi, Ltd. Japan) was employed to detect the level of alanine transaminase (ALT), while aspartate transaminase (AST) was determined using the rate method. Albumin (ALB) concentration was measured using bromocresol green method, while total bilirubin (TBIL) was measured using the diazo method. Blood urea nitrogen (BUN) level was ascertained using HMMPS method, and serum creatinine (CER) was determined using the uric acid method. The dynamics of blood flow [portal vein diameter (PVD), splenic vein diameter (SVD), portal vein flow (PVF), and portal vein velocity PVV)] were determined using color Doppler ultrasound (ACUSON Antares, Siemens AG, Germany) with 5.0 MHz wide-screen concave array probe.

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Publication 2023

Activated Partial Thromboplastin Time Alanine Transaminase Albumins Bilirubin Blood Circulation Bromcresol Green Child Coagulation, Blood Creatinine Diabetes Mellitus fibrin fragment D Fibrinogen Hemoglobin High Blood Pressures Immunoturbidimetry Operative Surgical Procedures Patients Serum Splenectomy Times, Prothrombin Transaminase, Serum Glutamic-Oxaloacetic Ultrasounds, Doppler Urea Nitrogen, Blood Uric Acid Veins Veins, Portal Veins, Splenic

Bone Regeneration in Critical-Sized Defects

Protocol full text hidden due to copyright restrictions

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Publication 2023

Bone Regeneration Bones Dental Health Services Diet Drill fluorexon Infection Injections, Intraperitoneal Intramuscular Injection Parietal Bone Penicillins Pentobarbital Sodium Rattus norvegicus Response, Immune Skin Spleen Splenectomy Sutures Tetracycline

Metabolic Factors in Type 2 Diabetes

A total of 95 volunteers were recruited from April 1, 2019 to June 30, 2022, including 36 females (17 T2DM patients, 19 normal controls) and 59 males (30 T2DM patients, 29 normal controls). T2DM Patients ranged from 32 to 71 years old (51.32 ± 10.60). The normal control group ranged from 31 to 68 years old (51.28 ± 8.91). Inclusion criteria: (1) patients diagnosed with T2DM and healthy volunteers with similar age to T2DM patients ( ± 3 years old) and no related diseases. Exclusion criteria: (1) patients unable to participate in MRI examination due to contraindications or other reasons; (2) patients with liver and pancreatic tumors; (3) patients after splenectomy; (4) patients with abnormal metabolic function or metabolic diseases excluding T2DM; (5) patients with hepatitis virus or hepatitis B, and liver iron deposition; (6) patients with liver trauma or patients receiving a liver transplant; (7) patients with pancreatic inflammation and alcoholics; (8) Patients with a history of drug therapy for the the pancreas (Sulfonamides, azathioprine, glucocorticoids, thiazide diuretics) and liver (Platinum agents, antibiotics, alkylating agents, antipsychotics, anti-tuberculosis drugs, and anti-tumor drugs) within six months. This study was conducted in accordance with the principles of the Declaration of Helsinki and approved by the hospital Ethics Committee (NO.2022-E460-01).

Yi J., Xu F., Li T., Liang B., Li S., Feng Q, & Long L. (2023). Quantitative study of 3T MRI qDixon-WIP applied in pancreatic fat infiltration in patients with type 2 diabetes mellitus. Frontiers in Endocrinology, 14, 1140111.

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Publication 2023

Alcoholics Alkylating Agents Antibiotics Antineoplastic Agents Antipsychotic Agents Antitubercular Agents Azathioprine Ethics Committees, Clinical Females Glucocorticoids Healthy Volunteers Hepatitis B Hepatitis Viruses Iron Liver Liver Transplantations Males Metabolic Diseases Pancreas Pancreatic Neoplasm Pancreatitis Patients Pharmacotherapy Platinum Splenectomy Sulfonamides Thiazide Diuretics Voluntary Workers Wounds and Injuries

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Ficoll-Paque PLUS is a sterile, ready-to-use medium for the isolation of mononuclear cells from blood or bone marrow by density gradient centrifugation. It is a polysucrose and sodium diatrizoate solution with a density of 1.077 g/mL.

Rpmi 1640 by Thermo Fisher Scientific

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RPMI 1640 is a common cell culture medium used for the in vitro cultivation of a variety of cells, including human and animal cells. It provides a balanced salt solution and a source of essential nutrients and growth factors to support cell growth and proliferation.

Fetal bovine serum (fbs) by Thermo Fisher Scientific

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Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.

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C57BL/6J mice are a widely used inbred mouse strain. They are a commonly used model organism in biomedical research.

What are some common reasons for undergoing a splenectomy?

What are the different surgical approaches for a splenectomy?

Splenectomies can be performed through open surgery or minimally invasive techniques. Open splenectomy involves making a larger incision to access and remove the spleen, while laparoscopic splenectomy uses smaller incisions and specialized tools to perform the procedure in a less invasive manner. Laparoscopic splenectomy is often associated with a faster recovery time for patients.

What are the potential risks and complications of a splenectomy?

One of the primary risks of splenectomy is an increased susceptibility to certain infections, as the spleen plays a crucial role in the body's immune system. Patients who undergo splenectomy may require lifelong antibiotic prophylaxis and close monitoring to manage this heightened infection risk. Other potential complications include bleeding, blood clots, and the risk of injury to surrounding organs during the procedure.

How can PubCompare.ai assist with splenectomy research?

PubCompare.ai's AI-driven platform can help researchers optimize their splenectomy studies in several ways. First, it allows you to efficiently screen the literature and identify the most relevant protocols related to splenectomy. The platform's intelligent search and comparison tools can pinpoint critical insights, enabling you to choose the most effective protocols for your specific research goals. Secondly, PubCompare.ai's cutting-edge analysis can highlight key differences in protocol effectiveness, helping you select the best options for reproducibility and accuracy in your splenectomy research.

Are there any new or emerging techniques in splenectomy procedures?

Reserach into splenectomy techniques is ongoing, with a focus on improving outcomes and reducing complications for patients. One area of innovation is the development of robotic-assisted splenectomy, which combines the precision of robotics with the minimally invasive approach of laparoscopic surgery. This technique may offer enhanced visualization and dexterity for the surgeon, potentially leading to faster recoveries and lower complication rates for patients.

More about "Splenectomy"

Splenectomy is a surgical procedure that involves the removal of the spleen, a crucial organ located in the upper left part of the abdomen.
The spleen plays a vital role in the body's immune system and blood filtration.
This procedure may be performed as a treatment for various conditions, such as an enlarged or damaged spleen, certain blood disorders, or splenic injuries.
The surgery can be done through open surgery or minimally invasive techniques like laparoscopic splenectomy.
Patients undergoing splenectomy may require lifelong antibiotic prophylaxis and close monitoring to manage the increased risk of infection due to the absence of the spleen.
Researchers are actively investigating optimal splenectomy protocols and techniques to improve outcomes and reduce complications for patients.
To support splenectomy research, various tools and materials are commonly utilized, such as Ficoll-Paque PLUS for cell separation, RPMI 1640 medium for cell culture, and fetal bovine serum (FBS) as a supplement.
Statistical software like SAS version 9.4 and Prism may be employed for data analysis, while animal models like C57BL/6 male mice and BALB/c mice are often used in preclinical studies.
SPSS statistical software is another popular choice for data analysis in splenectomy research.
Overall, the field of splenectomy is constantly evolving, with researchers and clinicians working to optimize surgical techniques, improve patient outcomes, and further our understanding of the spleen's role in health and disease.