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Vagus Nerve Stimulation

Vagus Nerve Stimulation: Unravel the potential of this powerful neuromodulation technique.
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Most cited protocols related to «Vagus Nerve Stimulation»

1
Vagus Nerve Stimulation in Rats
Cited 6 times

Protocol full text hidden due to copyright restrictions

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Publication 2015
Acoustics Impedance, Electric Neoplasm Metastasis Operative Surgical Procedures Pulse Rate Pulses Rattus norvegicus Sound Vagus Nerve Stimulation
2
Vagus Nerve Stimulation in Rats
Cited 6 times
All subjects underwent headcap and VNS cuff implantations, as previously described [3 (link)–5 , 7 (link), 12 (link)]. Immediately following lesion surgery, a two channel connector was attached with acrylic to four skull screws. An incision and blunt dissection of the neck exposed the left cervical vagus nerve. Stimulation of the left branch of the vagus avoids cardiac complications [4 (link), 5 , 7 (link)]. The nerve was placed inside the cuff (5-6 kΩ impedance), and cuff leads were tunneled subcutaneously and attached to the two-channel connector atop the skull. Rats were provided amoxicillin (5 mg) and carprofen (1 mg) for three days following surgery.
Hays S.A., Khodaparast N., Ruiz A., Sloan A.M., Hulsey D.R., Rennaker RL I.I, & Kilgard M.P. (2014). The timing and amount of vagus nerve stimulation during rehabilitative training affect post-stroke recovery of forelimb strength. Neuroreport, 25(9), 682-688.
Publication 2014
Amoxicillin carprofen Cranium Heart Neck Neck Dissection Nervousness Operative Surgical Procedures Ovum Implantation Pneumogastric Nerve Rattus norvegicus Vagus Nerve Stimulation
3
Defibrillation Protocols for Cardiac Arrhythmias
Cited 6 times
Experiments were conducted in open-chest anesthetized dogs or in isolated arterially perfused canine atrial and ventricular preparations in vitro (see methods). Atrial fibrillation was induced in vivo using rapid pacing during stimulation of the right vagus nerve (2–4 mA at 10 Hz) and in vitro during perfusion with acetylcholine (1–3 µM). Ventricular fibrillation was induced in vitro using rapid pacing. Membrane potential was recorded in vitro by optical mapping using a voltage-sensitive dye (di-4-anepps). Standard 6.5F cardioversion catheters were used to deliver defibrillation shocks in vivo and in vitro. The shocks consisted of 1–5 symmetrical biphasic pulses of 8 ms duration at shock strengths of 20–100 V delivered via a custom-built cardioverter/defibrillator. Immediately following the optical mapping experiments, tissues were injected with 1–2 mL of Microfil contrast agent at 0.05–0.15 mL/min via the same cannula used for perfusion. The chambers were then filled with silicone to preserve tissue morphology during scans performed using a GE 120 micro-CT scanner with 25 µm x-y-z resolution to determine blood vessel sizes and distributions.
Luther S., Fenton F.H., Kornreich B.G., Squires A., Bittihn P., Hornung D., Zabel M., Flanders J., Gladuli A., Campoy L., Cherry E.M., Luther G., Hasenfuss G., Krinsky V.I., Pumir A., Gilmour RF J.r, & Bodenschatz E. (2011). Low-energy Control of Electrical Turbulence in the Heart. Nature, 475(7355), 235-239.
Publication 2011
1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine Acetylcholine Atrial Fibrillation Blood Vessel Canis familiaris Cannula Catheters CAT SCANNERS X RAY Chest Contrast Media Defibrillators Electric Countershock Heart Atrium Heart Ventricle Membrane Potentials Microfil Perfusion Pulses Radionuclide Imaging Shock Silicones Tissues Vagus Nerve Stimulation Ventricular Fibrillation Vision
4
Defibrillation Protocols for Cardiac Arrhythmias
Cited 6 times
Experiments were conducted in open-chest anesthetized dogs or in isolated arterially perfused canine atrial and ventricular preparations in vitro (see methods). Atrial fibrillation was induced in vivo using rapid pacing during stimulation of the right vagus nerve (2–4 mA at 10 Hz) and in vitro during perfusion with acetylcholine (1–3 µM). Ventricular fibrillation was induced in vitro using rapid pacing. Membrane potential was recorded in vitro by optical mapping using a voltage-sensitive dye (di-4-anepps). Standard 6.5F cardioversion catheters were used to deliver defibrillation shocks in vivo and in vitro. The shocks consisted of 1–5 symmetrical biphasic pulses of 8 ms duration at shock strengths of 20–100 V delivered via a custom-built cardioverter/defibrillator. Immediately following the optical mapping experiments, tissues were injected with 1–2 mL of Microfil contrast agent at 0.05–0.15 mL/min via the same cannula used for perfusion. The chambers were then filled with silicone to preserve tissue morphology during scans performed using a GE 120 micro-CT scanner with 25 µm x-y-z resolution to determine blood vessel sizes and distributions.
Luther S., Fenton F.H., Kornreich B.G., Squires A., Bittihn P., Hornung D., Zabel M., Flanders J., Gladuli A., Campoy L., Cherry E.M., Luther G., Hasenfuss G., Krinsky V.I., Pumir A., Gilmour RF J.r, & Bodenschatz E. (2011). Low-energy Control of Electrical Turbulence in the Heart. Nature, 475(7355), 235-239.
Publication 2011
1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine Acetylcholine Atrial Fibrillation Blood Vessel Canis familiaris Cannula Catheters CAT SCANNERS X RAY Chest Contrast Media Defibrillators Electric Countershock Heart Atrium Heart Ventricle Membrane Potentials Microfil Perfusion Pulses Radionuclide Imaging Shock Silicones Tissues Vagus Nerve Stimulation Ventricular Fibrillation Vision
5
Transcutaneous Vagus Nerve Stimulation Protocol
Cited 5 times

Protocol full text hidden due to copyright restrictions

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Publication 2019
ARID1A protein, human Common Carotid Artery Electric Conductivity Medical Devices Neck Pain Pulses Short Interspersed Nucleotide Elements Skin Vagus Nerve Stimulation

Most recents protocols related to «Vagus Nerve Stimulation»

1
Epilepsy Surgery Outcomes in Japan
We reviewed the records of consecutive patients aged >10 years with drug‐resistant focal epilepsy who underwent evaluations for epilepsy surgery between March 2010 and December 2019 at the NHO Shizuoka Institute of Epilepsy and Neurological Disorders in Japan. We included patients who had undergone resective surgery and excluded those who had undergone palliative surgery (such as corpus callosotomy and vagus nerve stimulation) or surgery that was performed across the cerebral lobes. A total of 370 patients who had undergone epilepsy surgery were identified. Patients who achieved a favorable seizure outcome at least 2 years after surgery (Engel class I) were included. A total of 240 patients satisfied the above criteria and were included in this retrospective study. We divided the patients with surgically defined EZ into three groups: EZ on frontal lobe, temporal lobe, and posterior cortex (parietal or occipital lobe). We defined extra‐FLE as EZ on temporal lobe and posterior cortex, and extra‐TLE as EZ on frontal lobe and posterior cortex.
All patients underwent presurgical evaluation including long‐term video‐electroencephalogram (EEG) monitoring, 1.5 or 3 Tesla magnetic resonance imaging (MRI), and single‐photon emission computed tomography (SPECT) and/or [18F] fluorodeoxyglucose positron emission tomography. Long‐term video‐EEG monitoring was performed using the EEG‐1000 instrument (Nihon Kohden), and the standard 10–20 system of electrode placement was used in all cases. T1 and T2 or sphenoidal electrodes were added when necessary. In some patients, the Wada test or a functional MRI was undergone to determine the dominant hemisphere for language/speech functions. Additional intracranial electrode was conducted to determine the EZ and the extent of resection when the EZ could not be sufficiently identified and/or in the absence of a clear lesion on MRI after estimating the EZ based on the above evaluations.
This retrospective study was reviewed and approved by the Ethics Committee of the NHO Shizuoka Institute of Epilepsy and Neurological Disorders (2021–28).
Tanno Y., Matsudaira T., Usui N., Ogawa H., Tokumoto K., Kawaguchi N., Kondo A., Nishida T, & Takahashi Y. (2023). Periictal water drinking revisited: Occurrence and lateralizing value in surgically confirmed patients with focal epilepsy. Epilepsia Open, 8(1), 173-182.
Full text: Click here
Publication 2023
Cortex, Cerebral Drug Resistant Epilepsy Electroencephalography Epilepsy Ethics Committees F18, Fluorodeoxyglucose Lobe, Frontal Nervous System Disorder Occipital Lobe Operative Surgical Procedures Palliative Surgery Patients Positron-Emission Tomography Seizures Speech Sphenoid Bone Temporal Lobe Tomography, Emission-Computed, Single-Photon Vagus Nerve Stimulation
2
EEG Patterns in Neuropsychiatric Disorders
Electronic medical health records (EMHR) were used to identify all participants that underwent at least one EEG examination between the years 2011 and 2019. The participants were then divided into the following groups: control participants undergoing EEG due to indications unrelated to neuropsychiatric diseases, participants with a diagnosis of major depressive disorder (MDD) and patients diagnosed with schizophrenia. A total of 166 participants (average age: 52.4 ± 18.7 years; range: 18–91 years; 98 (59.4%) female) were included in the study:

Controls: Participants (n = 96; age: 52.2 ± 16.8 years; range: 19–80 years; 63 females) undergoing EEG due to indications unrelated to neuropsychiatric diseases. Exclusion criteria for this group included diagnosis of depression or schizophrenia, bipolar disorder, substance abuse, psychiatric or general medical conditions requiring hospitalization, history of epilepsy or conditions requiring anticonvulsants, ECT, vagal nerve stimulation, or transcranial magnetic stimulation (TMS), history of traumatic brain injury and history or imaging findings of cerebrovascular diseases including ischaemic and haemorrhagic stroke.

Depression: Participants with a diagnosis of major depressive disorder (MDD) hospitalized during the index time. This diagnosis had been established by two senior psychiatrists according to DSM-IV and DSM-V criteria following a psychiatric interview where the severity of depression was found to be at least moderate. In addition, the participants (n = 28; age: 69.7 ± 14.8 years; range: 33–91 years; 20 females) had to have had at least 1 previous major depressive episode, prior to age 30—namely, the index episode was a recurrent one.

Schizophrenia: Diagnosis of schizophrenia had been established by two senior psychiatrists according to the ICD-10 criteria. In addition, the participants (n = 42; age: 41.4 ± 16.8 years; range: 18–76 years; 15 females) had to be hospitalized during the index time.

Shor O., Yaniv-Rosenfeld A., Valevski A., Weizman A., Khrennikov A, & Benninger F. (2023). EEG-based spatio-temporal relation signatures for the diagnosis of depression and schizophrenia. Scientific Reports, 13, 776.
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Publication 2023
Anticonvulsants Bipolar Disorder Cerebrovascular Disorders Diagnosis Epilepsy Females Hemorrhagic Stroke Hospitalization Patients Psychiatrist Schizophrenia Stimulation, Transcranial Magnetic Substance Abuse Traumatic Brain Injury Unipolar Depression Vagus Nerve Stimulation Woman
3
Exclusion Criteria for Depressive Disorder Trials

Depressive episodes secondary to a systemic disease or neurological disorder, such as depression due to hypothyroidism.

Received modified electric convulsive therapy (MECT), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS) or vagus nerve stimulation (VNS) within 3 months before screening.

Withdrawal of psychotropic drugs did not equate to seven half-life periods before the screening.

Women with a positive blood human chorionic gonadotropin (HCG)/urine HCG test; men with reproductive potential and women of reproductive age unable to use contraception effectively and women who plan to become pregnant within 3 months of the start of the study.

Participated in any interventional clinical trial 3 months before screening.

Zhou J., Xu J., Liu R., Qi H., Yang J., Guo T., Zhou J., Zhu X., Zhang L., Chen X., Lyu N., Feng Z., Zhang G., Liu M., Wang W., Wang Y., Zhang Z., Xiao L., Feng Y, & Wang G. (2023). A prospective cohort study of depression (PROUD) in China: rationale and design. Current Medicine (Cham, Switzerland), 2(1), 1.
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Publication 2023
Contraceptive Methods Deep Brain Stimulation Electroconvulsive Therapy Hematologic Tests Human Chorionic Gonadotropin Hypothyroidism Nervous System Disorder Psychotropic Drugs Reproduction Stimulation, Transcranial Magnetic Urine Vagus Nerve Stimulation Woman
4
Exclusion Criteria for Psychiatric Disorders
In both studies, volunteers were excluded if they met lifetime DSM-V criteria for MDD with psychotic features, bipolar disorder, schizophrenia, or schizoaffective disorder, or if they had manifested drug/alcohol use disorder of at least moderate severity within 6 months. Patients who had received vagal nerve stimulation, electroconvulsive therapy, transcranial magnetic stimulation, or deep brain stimulation were excluded from participation. Patients currently receiving stimulants, anticonvulsants, or mood stabilizers were excluded. Additionally, women who were pregnant or planning to become pregnant during screening were excluded.
Vairavan S., Rashidisabet H., Li Q.S., Ness S., Morrison R.L., Soares C.N., Uher R., Frey B.N., Lam R.W., Kennedy S.H., Trivedi M., Drevets W.C, & Narayan V.A. (2023). Personalized relapse prediction in patients with major depressive disorder using digital biomarkers. Scientific Reports, 13, 18596.
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Publication 2023
Anticonvulsants Bipolar Disorder Central Nervous System Stimulants Deep Brain Stimulation Electroconvulsive Therapy Mental Disorders Mood Patients Schizoaffective Disorder Schizophrenia Stimulation, Transcranial Magnetic Substance Use Disorders Vagus Nerve Stimulation Voluntary Workers Woman
5
Comprehensive Neurosurgical Intervention Protocols
For the analysis, the interventions were divided into subgroups: (I) spinal pathology (degenerative diseases of the spine, lesions of the spine), (II) lesions of the brain (any supra- or infratentorial brain tumours, abscesses, cysts or similar pathologies), (III) ventriculoperitoneal drainage, (IV) cranioplasty, (V) procedures in functional neurosurgery (spinal cord stimulation, battery replacement, vagus nerve stimulation, deep brain stimulation), (VI) vascular pathology (aneurysms, arteriovenous malformations…) and (VII) endonasal endoscopy (pituitary adenoma, Rathke’s cyst, clivus chordoma, craniopharyngioma). Any procedure that required immediate surgical intervention was considered vital or emergency surgery. This included any form of acute cerebral haemorrhage (subdural, epidural or intracerebral), placement of external ventricular drainage or intracranial pressure monitoring, decompressive craniectomy and removal of a chronic subdural haematoma, or vital spinal disease.
Munda M., Velnar T., Bosnjak R., Zele T., Gradisnik L., Spazzapan P., Kos N., Kocivnik N., Benedicic M, & Prestor B. (2023). COVID-19 and Surgical Practice in Slovenia: Managing the Crisis in Neurosurgery during the COVID-19 Pandemic. Life, 13(10), 2095.
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Publication 2023
Abscess Aneurysm Arteriovenous Malformation Blood Vessel Brain Brain Neoplasms Cerebral Hemorrhage Chordoma Clivus Craniopharyngioma Cyst Decompressive Craniectomy Deep Brain Stimulation Drainage Emergencies Endoscopy Heart Ventricle Hematoma, Subdural, Chronic Intracranial Pressure Neurosurgical Procedures Operative Surgical Procedures Pituitary Adenoma Spinal Cord Stimulation Spinal Diseases Subdural Space Tumor, Infratentorial Vagus Nerve Stimulation Vertebral Column

Top products related to «Vagus Nerve Stimulation»

1
Model 2200 by A-M Systems
Sourced in United States
The Model 2200 is a high-precision electrical stimulator designed for a variety of laboratory applications. It features adjustable current and voltage outputs, and supports both constant current and constant voltage modes of operation.
2
C57bl 6 mice by Taconic Biosciences
Sourced in United States, Denmark, United Kingdom
C57BL/6 mice are a widely used inbred mouse strain. They are a commonly used laboratory mouse model for a variety of research applications.
3
Nim response 3 by Medtronic
Sourced in United States
The NIM-Response 3.0 is a medical device designed for intraoperative nerve monitoring. It provides real-time feedback on the functional status of nerves during surgical procedures. The device can be used to detect, identify, and monitor the functional integrity of motor and sensory nerves.
4
Prism software by GraphPad
Sourced in United States, United Kingdom, Belgium, Austria, Lao People's Democratic Republic, Canada, Germany, France, Japan, Israel
Prism software is a data analysis and graphing tool developed by GraphPad. It is designed to help researchers and scientists visualize, analyze, and present their data. Prism software provides a range of statistical and graphical capabilities to help users interpret their experimental results.
5
Vetbutal by Biowet
Sourced in Poland
Vetbutal is a laboratory equipment product that serves as a general anesthetic for veterinary use. It is designed to provide safe and effective sedation for animals during medical procedures or other situations requiring anesthesia. Vetbutal's core function is to induce a state of unconsciousness and pain relief in animals.
6
Fc block by BD
Sourced in United States, United Kingdom, Germany, Australia, France, Uruguay, Canada
The Fc block is a laboratory equipment designed to block Fc receptors. It functions as a tool to prevent non-specific binding of antibodies during various immunological assays and experiments.
7
D70eee by Data Sciences International
Sourced in Sao Tome and Principe
The D70EEE is a scientific instrument designed for laboratory use. It serves as a data acquisition and control system, facilitating the collection and analysis of experimental data. The device features precision sensors, interface connections, and software for streamlined data management. Further details on the intended use or specific applications of this product are not available.
8
Grass s88 stimulator by Natus
Sourced in United States
The Grass S88 stimulator is a laboratory equipment device designed for electrical stimulation applications. It generates electrical pulses and signals for various research and experimental purposes.
9
Mousestat jr by Kent Scientific
Sourced in United States
The MouseSTAT Jr. is a compact and portable physiological monitoring system designed for preclinical research applications. It provides real-time monitoring of vital signs, including heart rate, respiration rate, and body temperature, in small animal models such as mice. The device is designed for ease of use and reliable data collection to support various research studies.
10
Image studio by LI COR
Sourced in United States, United Kingdom, Germany
Image Studio is a software application that enables the analysis and quantification of data from a variety of imaging platforms, including those produced by LI-COR. The software provides tools for visualizing, processing, and interpreting image data, facilitating the scientific workflow.

More about "Vagus Nerve Stimulation"

Vagus Nerve Stimulation (VNS) is a powerful neuromodulation technique that has garnered significant interest in the scientific community.
The vagus nerve, a crucial component of the parasympathetic nervous system, plays a vital role in regulating various physiological functions, including heart rate, digestion, and immune response.
By stimulating the vagus nerve, researchers can harness its potential to unlock new insights and accelerate their studies.
PubCompare.ai's AI-driven platform offers a comprehensive solution for researchers exploring the realm of VNS.
The platform's intuitive and efficient tools empower researchers to navigate a wealth of literature, preprints, and patents, locating optimal research protocols and methodologies.
Leveraging cutting-edge comparisons, researchers can identify the best products and techniques for their VNS studies, whether they're using C57BL/6 mice, the NIM-Response 3.0 system, or the Grass S88 stimulator.
By exploring the power of VNS with PubCompare.ai, researchers can unlock new avenues of discovery.
The platform's AI-driven insights can help researchers identify the most effective protocols, such as those utilizing Vetbutal or Fc block, to achieve their research goals.
With the ability to analyze vast amounts of data, PubCompare.ai's tools can assist researchers in uncovering novel applications of VNS, from the study of the MouseSTAT Jr. to the use of D70EEE in their experiments.
Dive into the world of Vagus Nerve Stimulation with PubCompare.ai and unleash the full potential of this powerful neuromodulation technique.
Leverage the platform's cutting-edge comparisons and AI-driven insights to accelerate your research, unlock new discoveries, and stay ahead of the curve in this rapidly evolving field.