Citronellol

Manufactured by Tokyo Chemical Industry

Sourced in Japan

Citronellol is an organic compound with the chemical formula C₁₀H₂₀O. It is a colorless liquid with a floral, rose-like odor. Citronellol is commonly used as a fragrance ingredient in various consumer products.

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Lab products found in correlation

Limonene, by Tokyo Chemical Industry (1 mentions) Antibody against gapdh, by Cell Signaling Technology (1 mentions) Sodium pyruvate, by Thermo Fisher Scientific (1 mentions) 3 4 5 dimethylthiazol 2 yl 2 5 diphenyltetrazolium bromide mtt, by Merck Group (1 mentions) Streptomycin, by Thermo Fisher Scientific (1 mentions) Penicillin, by Thermo Fisher Scientific (1 mentions) Fetal bovine serum (fbs), by Thermo Fisher Scientific (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Mccoy s medium, by Thermo Fisher Scientific (1 mentions) Geraniol, by Tokyo Chemical Industry (1 mentions) Geraniol, by Fujifilm (1 mentions) Crystal violet, by Merck Group (1 mentions) Mueller hinton broth (mhb), by BD (1 mentions) N formyl met leu phe fmlp, by Merck Group (1 mentions) Phenethyl alcohol, by Fujifilm (1 mentions)

2 protocols using citronellol

Essential Oils and SARS-CoV-2 Inhibition

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All the essential oils were provided by Bio-Jourdeness International Groups Co. Ltd. (Taichung Taiwan). Citronellol, geraniol, neryl acetate, and limonene were obtained from Tokyo Chemical Industry Co., Ltd. (Tokya, Japan). Purity of these compounds were above 99%, according to the GC and ¹H-NMR analysis. McCoy’s medium, fetal bovine serum (FBS), sodium pyruvate, penicillin, and streptomycin were obtained from Invitrogen (Carlsbad, CA, USA). 3-(4,5-Dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and dimethylsulfoxide (DMSO) were purchased from Sigma-Aldrich. Antibody against ACE2 was obtained from Arigo Biolaboratories (Hsinchu, Taiwan). Antibody against GAPDH was obtained from Cell Signaling Technology Inc. All other chemicals were reagent grade or HPLC grade and were supplied by either Merck or Sigma-Aldrich.

Senthil Kumar K.J., Gokila Vani M., Wang C.S., Chen C.C., Chen Y.C., Lu L.P., Huang C.H., Lai C.S, & Wang S.Y. (2020). Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells. Plants, 9(6), 770.

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Rose-Derived Compounds Biological Activity

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Agents Rose water and rose oil were gifts from Bulgaria Rose Japan Ltd. (Tokyo, Japan, lot: 153 and 61, respectively). According to the company's analytical certificates, the main constituents of rose oil are Citronellol (31.47%), geraniol (19.10%), nerol (9.68%), and phenethyl alcohol (1.52%). The essential oil content in rose water was 0.095%, the main constituents of which were phenethyl alcohol (43.65%), Citronellol (18.24%), and geraniol (14.8%). Human recombinant tumor necrosis factor alpha (TNF-α), Dextran 200000, sodium dodecyl sulfate (SDS), geraniol, and phenethyl alcohol were purchased from Wako Pure Chemical Industries, Ltd. (Osaka, Japan). Citronellol was from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Roswell Park Memorial Institute medium (RPIM) 1640, lipopolysaccharide (LPS) (Escherichia coli Serotype 0127:B8), and N-formyl-Met-Leu-Phe (fMLP) were from Sigma-Aldrich Japan (Tokyo, Japan). Crystal violet (CV) was from Merck (Darmstadt, Germany). Fetal bovine serum (FBS) was from Thermo Trace (Melbourne, VIC, Australia). Mueller-Hinton broth was from Becton, Dickinson and Company (Sparks, MD, U.S.A.).

Maruyama N., Tansho-Nagakawa S., Miyazaki C., Shimomura K., Ono Y, & Abe S. (2017). Inhibition of Neutrophil Adhesion and Antimicrobial Activity by Diluted Hydrosol Prepared from Rosa damascena. Biological & pharmaceutical bulletin, 40(2).

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