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Gentest human cyp1a1

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Gentest human CYP1A1 is a laboratory equipment product that measures the activity of the CYP1A1 enzyme, which is involved in the metabolism of various compounds, including environmental pollutants and certain drugs. The core function of this product is to provide a standardized and quantitative assessment of CYP1A1 activity, which can be useful in various research and clinical applications.

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Lab products found in correlation

D glucose 6 phosphate sodium salt, by Merck Group (2 mentions) β nicotinamide adenine dinucleotide phosphate sodiumsalt nadp, by Merck Group (2 mentions) Glucose 6 phosphate dehydrogenase, by Merck Group (2 mentions) Prism 6, by GraphPad (2 mentions) Cyp1a2, by BD (2 mentions) Cyp1b1, by BD (1 mentions)

Spelling variants of this product

CYP1A1 (5 citations) BD Gentest (4 citations)

2 protocols using gentest human cyp1a1

1

CYP1A1, CYP1A2, and CYP1B1 Supersomes Assay

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Gentest human CYP1A1, CYP1A2, and CYP1B1 supersomes were purchased from BD Biosciences (Franklin Lakes, NJ). D-Glucose 6-phosphate sodium salt, β-nicotinamide adenine dinucleotide phosphate sodium salt (NADP+), and glucose 6-phosphate dehydrogenase were purchased from Sigma-Aldrich Corporation. Other reagents in bioassays were purchased from Fisher Scientific International, Inc. Figures were plotted with Prism 6 (GraphPad Software, Inc., La Jolla, CA) as well as Microsoft Excel 2013.
Liu J., Pham P.T., Skripnikova E.V., Zheng S., Lovings L.J., Wang Y., Goyal N., Bellow S.M., Mensah L.M., Chatters A.J., Bratton M.R., Wiese T.E., Zhao M., Wang G, & Foroozesh M. (2015). A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2. Journal of medicinal chemistry, 58(16), 6481-6493.
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2

Cytochrome P450 Enzyme Assay

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Gentest human
CYP1A1, CYP1A2,
CYP1B1, and CYP2A6 supersomes and rat CYP2B1 supersomes were purchased
from BD Biosciences (Franklin Lakes, NJ). d-Glucose-6-phosphate
sodium salt, β-nicotinamide adenine dinucleotide phosphate sodium
salt (NADP+), and glucose-6-phosphate dehydrogenase were
purchased from Sigma-Aldrich Corporation. Other reagents in bioassays
were purchased from Fisher Scientific International, Inc. Figures
were plotted with Prism 6 (GraphPad Software, Inc., La Jolla, CA).
Goyal N., Liu J., Lovings L., Dupart P., Taylor S., Bellow S., Mensah L., McClain E., Dotson B., Sridhar J., Zhang X., Zhao M, & Foroozesh M. (2014). Ethynylflavones, Highly Potent, and Selective Inhibitors of Cytochrome P450 1A1. Chemical Research in Toxicology, 27(8), 1431-1439.
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