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Nonspecific sirna si ns

Manufactured by Santa Cruz Biotechnology
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Nonspecific siRNA (si-NS) is a laboratory tool used for gene silencing experiments. It serves as a control siRNA that does not target any specific gene. This product can be utilized to establish baseline responses in RNA interference (RNAi) studies.

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Lab products found in correlation

Lipofectamine, by Thermo Fisher Scientific (1 mentions) Lipofectamine reagent, by Thermo Fisher Scientific (1 mentions)

Spelling variants of this product

SiRNAs (95 citations) Nonspecific siRNA (12 citations) NS siRNA (3 citations) Si-NS (2 citations)

2 protocols using nonspecific sirna si ns

1

Evaluating KLF4 Knockdown Effects

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Nonspecific siRNA (si-NS) and the siRNAs specific for human KLF4 were purchased from Santa Cruz Biotechnology. Transfection was performed using Lipofectamine (Invitrogen) following the manufacturer’s instructions. After the indicated times of transfection, HBL-100 cells were harvested and subjected to Western blotting and MTS proliferation analysis.
Wang B., Zhao M.Z., Cui N.P., Lin D.D., Zhang A.Y., Qin Y., Liu C.Y., Yan W.T., Shi J.H, & Chen B.P. (2015). Krüppel-like factor 4 induces apoptosis and inhibits tumorigenic progression in SK-BR-3 breast cancer cells. FEBS Open Bio, 5, 147-154.
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2

Retinoid Receptor Knockdown in HUVECs

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Nonspecific siRNA (si-NS) and siRNAs specific for human RARα were purchased from Santa Cruz Biotechnology (CA, U.S.A.). Transfection was performed using Lipofectamine reagent (Invitrogen) following the manufacturer’s instructions. Twenty-four hours following transfection, HUVECs were treated with or without ATRA (10 μM). Cells were then harvested and prepared for a Western blotting assay.
Shi H., Yuan L., Yang H, & Zang A. (2017). The mechanism of all-trans retinoic acid in the regulation of apelin expression in vascular endothelial cells. Bioscience Reports, 37(6), BSR20170684.
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