Magnetom triotim 3t mr system

Neuroimaging data were acquired at the University of Pittsburgh using a Siemens MAGNETOM TrioTim 3T MR system. Functional data (240 volumes) were collected using a gradient-echo, echo-planar sequence (voxel size:3.2×3.2×3.1 mm, TR=2000 msec, TE=28 msec, FOV=205, FA=90◦, 39 slices), and structural data were collected using MPRAGE (voxel size:1×1×1mm, TR=2200 msec, TE=3.29 msec, FOV=256, FA=9, 192 slices). The two neuroimaging visits were completed 6 months apart.

Neuroimaging data were acquired using a Siemens MAGNETOM TrioTim 3T MR system. A high-resolution structural image (1×1×1mm) was acquired using MPRAGE (TR=2300 msec, TE=3.93 msec, FOV-256, FA=9 degrees, 192 slices). Blood oxygen-level dependent (BOLD) functional data were collected using a gradient-echo, echo-planar sequence (voxel size: 3.2×3.2×3.1mm, TR=2000 msec, TE=28 msec, FOV=205, FA=90°, 38 slices). These data comprised 178 volumes (TRs). A PC with E-prime software (Psychology Software Tools (PST), Pittsburgh, PA) controlled stimulus display.
Statistical Parametric Mapping software (SPM8; http://www.fil.ion.ucl.ac.uk/spm) was used to preprocess and analyze fMRI data. Preprocessing involved realignment, coregistration, segmentation, normalization into a standard stereotactic space (Montreal Neurologic Institute, MNI; http://www.bic.mni.mcgill.ca), and spatially smoothing using a Gaussian kernel (FWHM: 8mm).