Jsh23

DSS was purchased from MP Biomedicals (Santa Ana, CA, USA), AOM from Sigma-Aldrich (St. Louis, MO, USA), capecitabine tablets from Chia TaiTianqing Pharmaceutical Co. Ltd (Nanjing, China), Iscove’s Modified Dulbecco’s Medium (IMDM) from Sigma-Aldrich (St. Louis, MO, USA), fetal bovine serum (FBS) from Gibco (Grand Island, NY, USA), lipopolysaccharide (LPS) from Sigma Chemical Co. (St. Louis, MO, USA), recombinant Human TGF-β1 from Whiga (PeproTech Inc., USA), bicinchoninic acid (BCA) assay kits from Beyotime Biotechnology (Beijing, China), phycoerythrin (PE)-conjugated anti-CD11b, FITC-conjugated anti-Gr-1 and purified mouse Fc block (anti-CD16/CD32) from ThermoFisher Inc (Waltham, MA, USA)，Enzyme-Linked Immunosorbent Assays (ELISA) kits for IL-17, TGF-β, IL-6, tumor necrosis factor-α (TNF-α) and IL-1β from eBioscience (Waltham, MA, USA). NF-κB p-p65, p-STAT3, E-cadherin, snail, vimentin, and β-actin antibodies were purchased from Abcam, Inc (Cambridge, MA, USA). Goat Anti-rabbit IgG/Alexa Fluor 488 and Goat Anti-mouse IgG/Alexa Fluor 546 were purchased from Whiga (PeproTech Inc, USA). Goat Anti-rabbit IgG/HRP antibody was purchased from ZhongShanJinQiao Biological Technology Co (Beijing, China). Hoechst 33342 was purchased from ThermoFisher Inc (MA, USA). JSH23 was purchased from TargetMol((MA, USA).