Avance 1 300

Infrared spectra were measured on a Perkin Elmer Spectrum 100 Optica (Perkin Elmer, Wellesley, MA, USA). ¹H- and ¹³C-NMR spectra were recorded on a Bruker Avance III 200 spectrometer at 200 MHz and 50 MHz respectively, Bruker Avance I 300 at 300 MHz and 75 MHz respectively, on a Bruker Advance II 400 spectrometer at 400 MHz and 100 MHz respectively, on a Bruker Advance III 600 spectrometer at 600 MHz and 150 MHz respectively (Bruker, Billerica, MA, USA). Shifts (δ) are given in parts per million with respect to solvent residual peak and coupling constants (J) are given in Hertz. HRMS (FD) spectra were performed by CESAMO (Bordeaux, France). The measurements were carried out on a TOF mass spectrometer AccuTOFGCv using an FD emitter with an emitter voltage of 10 kV. One to two microliters solution of the compound is deposited on a 13 μm emitter wire. Elemental analyses were carried out by the “Institut de Chimie des Substances Naturelles” (Gif-sur-Yvette, France). Melting points were measured on Stuart SMP 10.DSC measures were carried out on Mettler Toledo DSC 1 STAReSystem (Mettler, Greifensee, Switzerland).

NMR-spectra were acquired using a Bruker Avance I 300 and Bruker Avance III 499. 1H NMR-spectra were acquired at a frequency of 300.1 MHz or 499.9 MHz, while 13C NMR-spectra were acquired at a frequency of 125.7 MHz. Peak assignments were assisted with two-dimensional spectra (H,H-COSY, H,C-HMBC, H,C-HMQC). The chemical shift σ and the coupling constant 3J or 4J are indicated in ppm and in Hz, respectively. The multiplicity is classified as singlet (s), doublet (d), triplet (t), doublet doublet (dd), triplet triplet (tt) and multiplet (m).