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Rosuvastatin calcium salt

Manufactured by Merck Group
Sourced in United States

Rosuvastatin calcium salt is a laboratory-grade chemical compound used as a reference standard or reagent in various analytical and research applications. It is the calcium salt form of rosuvastatin, a pharmaceutical active ingredient primarily used to lower cholesterol levels. The core function of rosuvastatin calcium salt is to serve as a reliable and well-characterized reference material for testing, method development, and quality control purposes in pharmaceutical and biomedical research.

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2 protocols using rosuvastatin calcium salt

1

Statin and Azacytidine Dissolution Assay

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Atorvastatin calcium salt trihydrate (CAS No. 134523038), cerivastatin sodium salt hydrate (CAS No. 143201110), rosuvastatin calcium salt (CAS No. 147098202), simvastatin (CAS No. 79902639), and 5-azacytidine (CAS No. 320672) were purchased from Sigma Aldrich, USA. All drugs dissolved in DMSO (Sigma Aldrich, St. Louis, MO, USA).
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2

Quantification of Regorafenib and Metabolites

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REG (CAS No. 755037-03-7), M-2, M-5, and REG-d3 (internal standard for the quantification of REG as well as M-2 and M-5) were purchased from LGC Standards (Łomianki, Poland). ATO as a calcium salt trihydrate (CAS No. 344423-98-9), ortho-and parahydroxylated ATO (as dihydrate monosodium and disodium salts, respectively) were purchased from Santa Cruz Biotechnology (Dallas, USA). Methanol, acetonitrile (liquid chromatography and mass spectroscopy grade), rosuvastatin calcium salt (internal standard for the quantification of both ATO and its metabolites), ammonium formate, ammonium acetate, and dimethyl sulfoxide (DMSO) were purchased from Sigma-Aldrich (Saint Louis, Missouri, USA). The water used in the mobile phase was deionized, distilled, and filtered through a Millipore system (Direct Q3, Millipore, USA) before use. REG (Stivarga
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