Deprenyl hydrochloride

Triapine was obtained from Selleckchem (Houston, TX), tenofovir was generously donated by Dr. Lisa Rohan (University of Pittsburgh). Methimazole, N-benzyl imidazole, chlorogyline, deprenyl hydrochloride, (+) raloxifene hydrochloride, carnitine acetyltransferase, acetyl DL-carnitine, acetyl coA, triethanolamine and allopurinol were obtained from Sigma Aldrich (St Louis, MO). Human liver microsomes, human liver mitochondria, and human liver cytosol with high aldehyde oxidase and xanthine oxidase activity were obtained from Xenotech (Kansas City, KS). human liver cytosol was obtained from Corning (Corning, NY). Plated primary human hepatocytes were obtained from the Department of Surgery at the University of Pittsburgh. (Suppl.Table 1). Furafylline, phenyl piperidinyl propane, montelukast, sulfaphenazone, tranylcypromine hydrochloride, emtricitabine, disulfiram, and 4-methyl pyrazole were obtained from Cayman Chemical (Ann Arbor, MI). [²H_6]-tenofovir and [²H₃, ¹⁵N]-emtricitabine were purchased from Alsachim (Illkirch-Graffenstaden, France). 3-Benzyl nirvanol was purchased from Santa Cruz Biotechnology (Dallas, TX). Quinidine was obtained from Alfa Aesar (Tewksbury, MA). All samples generated were stored at −20 °C or lower until further analysis.