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Strain b6.129p2 p2ry2tm1bhk j

Manufactured by Jackson ImmunoResearch

The strain B6.129P2–P2ry2tm1Bhk/J is a genetically modified mouse model. It is a knockout strain that carries a targeted mutation in the P2Y2 receptor gene (P2ry2). This model can be used for research purposes, but a detailed description of its core function without interpretation or extrapolation is not available.

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2 protocols using strain b6.129p2 p2ry2tm1bhk j

1

P2Y2 Receptor Knockout Mice

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Wild-type (WT) C57BL/6 mice (7 weeks old) were purchased from Koatech Co. (Pyeongtaek, South Korea), and homozygous P2Y2R knockout (KO) male mice on C57BL/6 background (strain B6.129P2–P2ry2tm1Bhk/J) were obtained from Jackson Laboratory. All mice were maintained in the animal facility at Gyeongsang National University. All animal experiments were approved by the Institutional Board of Animal Research at Gyeongsang National University and performed according to the National Institutes of Health guidelines for laboratory animal care. Mice were housed with an alternating 12-h light/dark cycle and provided with water and standard chow ad libitum.
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2

C57BL/6 Mice and P2Y2R Knockout

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WT C57BL/6 mice (6-week old) were purchased from Koatech Co. (Pyeongtaek, South Korea) and homozygous P2Y2R KO mice on C57BL/6 background (strain B6.129P2-P2ry2tm1Bhk/J) were obtained from Jackson Laboratory. All mice were maintained in the animal facility at Gyeongsang National University (GNU-171130-M0058). All animal experiments were approved by the Institutional Board of Animal Research at Gyeongsang National University, and performed according to the National Institutes of Health guidelines for laboratory animal care. Mice were housed with an alternating 12-h light/dark cycle and provided with water and standard chow ad libitum.
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