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C3h hej c3h h2k

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The C3H/HeJ (C3H; H2k) is a mouse strain that is homozygous for the Tlr4lps-d allele, which results in LPS hyporesponsiveness. This strain is commonly used as a control in studies involving the Toll-like receptor 4 (TLR4) signaling pathway.

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C3H (H2k) C3H/HeJ C3H/HeJ (C3H)

2 protocols using c3h hej c3h h2k

1

C57BL/6 and C3H Mouse Acquisition

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Male C57BL/6 (B6; H2b) and C3H/HeJ (C3H; H2k) mice were purchased from The Jackson Laboratory.
Nakano R., Yoshida O., Kimura S., Nakao T., Yokota S., Ono Y., Minervini M.I., Geller D.A, & Thomson A.W. (2021). Donor plasmacytoid dendritic cells modulate effector and regulatory T cell responses in mouse spontaneous liver transplant tolerance. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 21(6), 2040-2055.
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2

Mouse Strain Characteristics for Immunology

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All experimental procedures were approved by the Seoul National University Institutional Animal Care and Use Committee and were conducted according to the animal experiment ethical guidelines and regulations. All animals were aged 8 wk. Female C57BL/6 (B6, H-2b), BALB/c AnHsd (BALB/c, H-2d), and C3H/HeJ (C3H, H-2 K) inbred mice were purchased from the Jackson Laboratory (Bar Harbor, ME, USA). Female knock-in B6 (DEREG) mice expressing Forkhead box P3 (FoxP3) together with diphtheria receptor and enhanced green fluorescent protein (eGFP) were also purchased from the Jackson Laboratory. FoxP3 tagged with eGFP reporter mice were kindly provided by Alexander Y. Rudensky (Memorial Sloan Kettering Cancer Center, New York, NY, USA).
Lee S.J., Kim H.J., Byun N.R, & Park C.G. (2020). Donor-Specific Regulatory T Cell-Mediated Immune Tolerance in an Intrahepatic Murine Allogeneic Islet Transplantation Model with Short-Term Anti-CD154 mAb Single Treatment. Cell Transplantation, 29, 0963689720913876.
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