For the T1 image, the origin was set to the AC–PC plane and the images were segmented using the SPM12 segmentation procedure. The produced normalization parameters were then applied to all coregistered fMRI image volumes. Successful normalization to standard Montreal Neurological Institute (MNI) coordinate space was checked at random for each subject using ventricles and brain borders as landmarks. Finally, all fMRI image volumes were smoothed with an isotropic 8-mm full width half maximum Gaussian filter.
Spm12
SPM12 is a software package designed for the analysis and visualization of structural magnetic resonance imaging (MRI) data. It provides a comprehensive set of tools for preprocessing, modeling, and statistical inference on structural brain images. The core function of SPM12 is to enable researchers to perform advanced image analysis and quantification tasks related to structural MRI data.
Lab products found in correlation
80 protocols using spm12
Preprocessing and Analysis of fMRI Data
For the T1 image, the origin was set to the AC–PC plane and the images were segmented using the SPM12 segmentation procedure. The produced normalization parameters were then applied to all coregistered fMRI image volumes. Successful normalization to standard Montreal Neurological Institute (MNI) coordinate space was checked at random for each subject using ventricles and brain borders as landmarks. Finally, all fMRI image volumes were smoothed with an isotropic 8-mm full width half maximum Gaussian filter.
FDG-PET Image Preprocessing and Normalization
Neuroimaging Analysis of MRI Data
fMRI Data Analysis with SPM12 and BIDS
Evaluating Image Quality in Multimodal Imaging
Regarding MR images (T1WI and T2WI), we evaluated overall image quality using the following four-point score: 0 = poor (non-diagnostic quality); 1 = fair (low quality with distinct artifacts and strong noise); 2 = good (satisfactory quality with few artifacts or moderate noise); and 3 = excellent (no artifacts and low noise).
Regarding PET images, we evaluated overall image quality and sharpness considering artifact and noise (Table 1). For 12 patients with intracranial lesions, we examined the number of detected lesions and the subjective contrast of those lesions. We defined lesions as areas showing focal 18 F-FDG uptake that was increased or decreased compared with background physiological uptake in the brain.
Quantitative evaluation: registration accuracy and regional 18 F-FDG uptake accuracy For evaluation of registration accuracy and regional 18 F-FDG uptake accuracy, we measured the spatial coordinates and regional standardized uptake value (SUV), using SPM12 (https://www.fil.ion.ucl.ac.uk/spm/software/SPM12), MATLAB (R2016b, MathWorks, Natick, Massachusetts, Untied States) and ImageJ software (National Institutes of Health, Bethesda, Maryland, United States).
Voxel-Based and Surface-Based Neuroimaging Analysis
Preprocessing Pipeline for Structural and Functional MRI Data
Preprocessing RS-fMRI Data with DPABI
Neuronal Correlates of Controllability
A more detailed description of the experimental procedure, behavioral analyses, skin conductance and imaging analyses is provided in the supplemental material.
Neuroimaging of Depression Recovery
In a further analysis, the BDI-II (35 (link), 36 ) was added as a covariate to correct for the influence of depressiveness.
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