Invivovu

Manufactured by Bioptigen

InVivoVU is a lab equipment product developed by Bioptigen. It is a non-invasive, high-resolution imaging system designed for in vivo visualization and analysis of biological samples.

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Lab products found in correlation

Sd oct device, by Bioptigen (2 mentions)

3 protocols using invivovu

Retinal Thickness Measurement using SD-OCT

Cited 1 time

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A SD-OCT device (Bioptigen Inc. Durham. NC, USA) was used to record the retinal thickness ^{20 (link)}. Images were captured with the rectangular scan at 1000 A-scans per B-scan, and 100 B-scans per frame. Total retinal thickness (TRT) was measured perpendicular to the surface of retinal pigment epithelial (RPE) layer and retinal nerve fiber layer (RNFL) at 12, 3, 6, and 9 o’clock positions, 500 μm away from the center of optic nerve head (ONH) using the built-in software (InVivoVU, Bioptigen), and then averaged. The examiners were blinded to the treatment information.

Qiu F., Meng T., Chen Q., Zhou K., Shao Y., Matlock G., Ma X., Wu W., Du Y., Wang X., Deng G., Ma J.X, & Xu Q. (2019). Fenofibrate-Loaded Biodegradable Nanoparticles for the Treatment of Experimental Diabetic Retinopathy and Neovascular Age-Related Macular Degeneration. Molecular pharmaceutics, 16(5), 1958-1970.

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Retinal Layer Thickness Measurement via SD-OCT

Cited 2 times

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Spectral-domain (SD) -OCT device (Bioptigen Inc. Durham. NC, USA) was used to record the retinal layers thickness [30 (link), 31 (link)]. Images were captured with the rectangular scan at 1000 A-scans per B-scan, and 100 B-scans per frame. Total retinal thickness (TRT) was measured perpendicularly from the layer of retinal nerve fiber layer (RNFL) to the layer of outer segment (OS), 500 μm away from the center of optic nerve head (ONH) using the built-in software (InVivoVU, Bioptigen) and then averaged. The examiners were blinded to the treatment information.

Wang Y., Ma X., Muthuraman P., Raja A., Jayaraman A., Petrukhin K., Cioffi C.L., Ma J.X, & Moiseyev G. (2022). The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration. PLoS ONE, 17(10), e0269437.

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Quantitative Retinal Imaging and CNV Analysis

Cited 1 time

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OCT (Envisu^TM R-series SDOIS system, Bioptigen, Inc., Morrisville, NC, USA) imaging was performed after animals were anesthetized with pupils dilated. The corneal and retinal thickness were measured at 500 µm intervals temporal and nasal to the optic nerve head in all images obtained from both horizontal and vertical scans, using the system software (InVivoVU, Bioptigen, Inc.), and averaged [25 (link)]. For laser-induced CNV mice, the CNV volume was quantified using ImageJ based on the volume formula as described [20 (link),26 (link)].

Huang L., Liang W., Zhou K., Wassel R.A., Ridge Z.D., Ma J.X, & Wang B. (2021). Therapeutic Effects of Fenofibrate Nano-Emulsion Eye Drops on Retinal Vascular Leakage and Neovascularization. Biology, 10(12), 1328.

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