Mettl3

Manufactured by Solarbio

Sourced in China

METTL3 is a methyltransferase enzyme that catalyzes the addition of methyl groups to specific sites on RNA molecules. It plays a crucial role in the post-transcriptional modification of RNA and is involved in various cellular processes.

Automatically generated - may contain errors

Lab products found in correlation

Vimentin, by Solarbio (1 mentions) E cadherin, by Solarbio (1 mentions) Zbtb4, by Solarbio (1 mentions)

1 protocol using mettl3

Immunohistochemical Staining Protocol

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Tissues were fixed with 4% paraformaldehyde before being placed in paraffin. 5-μm sections were placed on the glass slide and stained for METTL3, E-cadherin, vimentin, or ZBTB4 (Solarbio Life Science, China) based on the manufacturer’s guidelines to detect the levels of METTL3, E-cadherin, vimentin, and ZBTB4. Quantitative IHC staining with the immunohistochemical score (IRS) system was as described previously.⁵³ (link)

Cheng C., Wu Y., Xiao T., Xue J., Sun J., Xia H., Ma H., Lu L., Li J., Shi A., Bian T, & Liu Q. (2020). METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung. Molecular Therapy. Nucleic Acids, 23, 487-500.

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