DTI, rs-fMRI, and T1-magnetization-prepared rapid gradient-echo (MPRAGE) images of all the subjects were obtained using a 3.0-Tesla MR scanner (Verio, Siemens with a Siemens matrix coil) under the supervision of an attending pediatrician. The DTI was performed using the following parameters: b = 0 and 800 s/mm; repetition time (TR), 13,000 ms; echo time (TE), 76 ms; flip angle, 90°; pixel bandwidth, 1628 Hz/pixel; total acquisition time, 14 min 33 s; and iso-voxel resolution, 1.8 mm. The rs-fMRI imaging parameters used were as follows: TR = 3000 ms, TE = 30 ms, in-plane voxel resolution = 3.4 × 3.4 mm 2, field-of-view = 220 mm × 220 mm, total acquisition time = 5 min 36 s, and slice thickness = 3.4 mm. Data were collected continuously at 110-time points, and the scanning range was the whole- brain. The T1-MPRAGE imaging parameters used were as follows: TR, 1900 ms; TE, 2.93 ms; flip angle, 8°; pixel bandwidth, 170 Hz/pixel; matrix size, 256 × 208; field-of-view, 256 mm; NEX, 1; slice thickness, 1 mm; total acquisition time, 4 min 9 s. For successful scanning without sedatives, scans were scheduled around the child's natural nap time. If the child failed to sleep naturally, a low dose of chloral hydrate (30 mg/kg) was orally administered.
Matrix coil
Manufactured by Siemens
Sourced in United States, Germany
The Matrix coil is a specialized lab equipment designed for electromagnetic field generation. It provides a controlled and uniform magnetic field within its defined spatial area. The core function of the Matrix coil is to generate a precise and adjustable magnetic field for various experimental and research applications.
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Lab products found in correlation
6 protocols using matrix coil
1
Multimodal Brain Imaging in Pediatric Subjects
2
3D T1-MPRAGE MRI Brain Imaging
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MRI of all participants was performed on a 3.0T MRI scanner (Verio, Siemens with a Siemens matrix coil) and included a 3D T1 magnetization-prepared rapid gradient-echo (MPRAGE) sequence. The 3D T1-MPRAGE imaging parameters used were as follows: repetition time=1,900 m/s, echo time=2.93 m/s, flip angle=8°, pixel bandwidth=170 Hz/pixel, matrix size=256×208, field of view=256 mm, total acquisition time=4 minutes 10 seconds, and an iso-voxel resolution of 1.0 mm.
3
3D MRI Acquisition and FreeSurfer Analysis
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3D T1-magnetization-prepared rapid gradient echo (repetition time: 1,810 ms, echo time: 2.91 ms, flip angle: 9°, pixel bandwidth: 340 Hz/pixel, matrix size: 512×512, field of view: 250 mm, number of excitations: 1, total acquisition time: 3 minutes 37 seconds, voxel size: 0.49×0.49×1.0 mm3) was acquired with a 3 T MRI scanner (Skyra, Siemens with a Siemens matrix coil). Images were analyzed using FreeSurfer 6.0 (www.surfer.nmr.mgh.harvard.edu ) to define regions of interest (ROIs) in the native space for each subject and to support the correction of grey matter (GM) atrophy and white matter spillover for subsequent PET image analysis.
4
Multi-Tracer PET Imaging of Neurodegenerative Diseases
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All participants underwent brain MRI using a 3.0-T MRI scanner (Verio, Siemens with a Siemens matrix coil) as described in our previous study (Kang et al., 2017 (link)). Both 18F-THK5351 and 18F-FLUTE PET scans were acquired using a Siemens Biograph 6 Truepoint PET/computed tomography scanner (Siemens, Knoxville, TN, USA) with a list-mode emission acquisition. THK5351 scans were acquired for 20 min starting from 50 min after the injection of 185MBq of 18F-THK5351 intravenously (50–0 min), which was synthesized and radiolabeled in Gachon University Neuroscience Research Institute. 18F-FLUTE emission scans were acquired for 20 min starting from 90 min after the intravenous injection of 185 MBq of 18F-FLUTE (90–110 min), purchased from Carecamp Inc. The mean interval between the PET scans was 13.94 ± 14.02 days and detailed data of interval between the two PET scans are presented in Appendix 1 in Supplementary Materials . Attenuation correction was performed with a low-dose CT scan and data reconstruction was performed with a 2D ordered subset expectation maximization algorithm (eight iterations and 16 subsets).
5
3D MRI Protocol for Neuroimaging
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MRI of all participants was performed with a 3.0-T MRI scanner (Siemens with a Siemens matrix coil; Verio, Orem, Utah, USA) including a 3-dimensional (3D) magnetization prepared rapid gradient echo (MPRAGE) sequence. Imaging parameters used for 3D MPRAGE were as follows: repetition time=1900 m/s, echo time=2.93 m/s, flip angle=8°, pixel bandwidth=170 Hz/pixel, total acquisition time=4 minutes 10 seconds, and the iso-voxel resolution was 1.0 mm. Other clinical MRI sequences including fluid attenuated inversion recovery sequence were also acquired.
6
Pediatric MRI Acquisition Protocol
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A 3.0-T Siemens scanner (Verio, Siemens, Germany) and a Siemens matrix coil were used. T1-magnetization-prepared rapid gradient-echo (MPRAGE) images of all participants were obtained under the supervision of an attending pediatrician. The T1-MPRAGE imaging parameters used were as follows: repetition time = 1900 ms; echo time = 2.93 ms; flip angle = 8°; pixel bandwidth = 170 Hz/pixel; matrix size = 256 × 208; field-of-view = 256 mm; number of excitations = 1; slice thickness = 1 mm; total acquisition time = 4 min 9 s. The MRI scans were scheduled around the child’s natural nap time to encourage successful scanning without using sedatives. In case of inability to fall asleep naturally, a low dose of chloral hydrate (30 mg/kg) was administered orally.
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