Span 80

Manufactured by Loba Chemie

Sourced in India

Span 80 is a non-ionic surfactant. It is a low-HLB (Hydrophilic-Lipophilic Balance) emulsifier commonly used in the formulation of water-in-oil emulsions.

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Lab products found in correlation

9 protocols using span 80

Formulation and Evaluation of Capsaicin Topical Gel

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Capsaicin was obtained from Plant Lipids Private Limited, Telangana, India. Mineral oil, clove oil, Carbopol 934, Tween 80, Span 80, triethanolamine, propylene glycol, methylparaben, propylparaben, and liquid paraffin were purchased from Loba Chemie, Mumbai. All the other chemicals were procured from HiMedia Lab, Mumbai, India. All the solvents were of High-Performance Liquid Chromatography (HPLC) grade.

Rompicherla N.C., Joshi P., Shetty A., Sudhakar K., Amin H.I., Mishra Y., Mishra V., Albutti A, & Alhumeed N. (2022). Design, Formulation, and Evaluation of Aloe vera Gel-Based Capsaicin Transemulgel for Osteoarthritis. Pharmaceutics, 14(9), 1812.

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Sunflower Oil Oleogel Preparation

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Commercial refined sunflower oil (Fortune sunlight, Kutch, Gujarat, India), used for the oleogel preparation, was purchased from the local supermarket. Sunflower wax pellet was procured from Vijay Impex, Chennimalai, Tamil Nadu, India. SPAN-80 and TWEEN-80 were purchased from Loba Chemie Pvt. Ltd., Mumbai, India, and Himedia Laboratories Pvt Ltd., Mumbai, India, respectively.

Bharti D., Kim D., Cerqueira M.A., Mohanty B., Habibullah S., Banerjee I, & Pal K. (2021). Effect of Biodegradable Hydrophilic and Hydrophobic Emulsifiers on the Oleogels Containing Sunflower Wax and Sunflower Oil. Gels, 7(3), 133.

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Chitosan-based Biocompatible Biomaterials

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The various reagents and chemicals such as chitosan, acetic acid, and ethanol were purchased from Sigma-Aldrich Chemical Limited (St. Louis, MO, USA); glutaraldehyde from Acuro Organics Limited (New Delhi, India); Span 80 from Lobachemie (Mumbai, Maharashtra, India); carboxymethyl cellulose from Paras Enterprises (Mumbai, Maharashtra, India); Ketamine from Troikaa Pharmaceuticals Limited (Ahmedabad, Gujarat, India); and xylazine from Alivira Animal Health (Thane, Maharashtra, India).

Garg S., Singla R.K., Rahman M.M., Sharma R, & Mittal V. (2022). Evaluation of Ulcer Protective Activity of Morus alba L. Extract-Loaded Chitosan Microspheres in Ethanol-Induced Ulcer in Rat Model. Evidence-based Complementary and Alternative Medicine : eCAM, 2022, 4907585.

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Optimizing Topical Capsaicin Formulations

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Capsaicin was provided as a gift sample by Naturite Agro Products Limited Hyderabad, India. Labrafil M1944CS, Caproyl PGMC, Labrasol was obtained from Gattefosse India Pvt. Ltd, France as a kind gift sample. Span 80, Span 20, Tween 20, isopropyl alcohol, polyethylene glycol (PEG) 200, PEG 400, PEG 600, ethyl oleate, Labrafil M1944CS, labrafac PG, castor oil, oleic acid, isopropyl myristate (IPM), cotton seed oil, soybean oil, & olive oil were procured from LobaChemie Pvt. Ltd, Mumbai, India. Cremophor EL & Cremophor RH40 was provided by BASF, Germany. All other chemicals used were of analytical grade.

Bhagwat D.A., Swami P.A., Nadaf S.J., Choudhari P.B., Kumbar V.M., More H.N., Killedar S.G, & Kawtikwar P.S. (2021). Capsaicin Loaded Solid SNEDDS for Enhanced Bioavailability and Anticancer Activity: In-Vitro, In-Silico, and In-Vivo Characterization. Journal of pharmaceutical sciences, 110(1).

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Formulation and Evaluation of Glibenclamide

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Aurobindo Pharma, Hyderabad, India, generously presented glibenclamide. Sodium trimetaphosphate, Span 80, and Tween 80 were procured from Loba Chemie Pvt Ltd.; Mumbai, India. 2-mercapto nicotinic acid (MA) and Triton X-100 were acquired from SD Fine-Chem Ltd. (Mumbai, India). The other chemicals and solvents used were of analytical grade.

Rizg W.Y., Naveen N.R., Kurakula M., Safhi A.Y., Murshid S.S., Mushtaq R.Y., Abualsunun W.A., Alharbi M., Bakhaidar R.B., Almehmady A.M., Salawi A., Al Fatease A, & Hosny K.M. (2022). Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies. Pharmaceuticals, 15(4), 491.

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Tramadol HCl Lipid-Based Formulation

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Tramadol HCl was obtained from Jackson Pharm. Pvt. Ltd, Amritsar. SPC was a kind gift from Lipoid, GmBH, Ludwigshafen. Span 80, sodium deoxycholate, Tween 80, Carbopol 934, Triton-X 100, triethanolamine, chloroform, and methanol were all purchased from Loba Chemie (P) Ltd, Mumbai, India.

Singh S., Vardhan H., Kotla N.G., Maddiboyina B., Sharma D, & Webster T.J. (2016). The role of surfactants in the formulation of elastic liposomal gels containing a synthetic opioid analgesic. International Journal of Nanomedicine, 11, 1475-1482.

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Curcumin-Piperine Nanoparticle Formulation

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Curcumin and piperine were procured from Lobachemie, Mumbai, India, and Sami Labs Ltd., Bangalore, India, respectively. Chitosan, span 80, and glacial acetic acid were obtained from Lobachemie, Mumbai. Eudragit S 100 was purchased from Evonik Pharma, Mumbai. All other chemicals and solvents were obtained from Merck Ltd, Mumbai.

Thomas G., & Koland M. (2022). Composition of Piperine with Enteric-Coated Chitosan Microspheres Enhances the Transepithelial Permeation of Curcumin in Sheep Intestinal Mucosa and Caco-2 Cells. Journal of Health and Allied Sciences NU, 12(03), 312-321.

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Formulation and Evaluation of Glimepiride

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Glimepiride was kindly provided by Swiss Garnier Life Sciences (Mehatpur, Una, Himachal Pradesh, India) as a gift sample. Acetone, dichloromethane, polyethylene glycol (PEG400, PEG6000), Span 80, Tween 80, polyvinyl pyrolidone (PVP K30), microcrystalline cellulose and sodium dodecyl sulphate were purchased from Loba Chemie Pvt. Ltd.
(Mumbai, India). All other chemicals and reagents were of analytical grade.

Bose S., Sharma P., Mishra V., Patial S., Saraogi G.K., Tambuwala M.M., & Dua K. (2021). Comparative in vitro evaluation of glimepiride containing nanosuspension drug delivery system developed by different techniques. Journal of Molecular Structure, 1231, 129927-129927.

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Piroxicam-loaded Soya Phospholipid Vesicles

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Piroxicam was a gift from Apex Healthcare Ltd, Ankleshwar, India. Soya phosphatidylcholine 70 (SPL 70) had been procured from Nabros Pharma Pvt Ltd, Ahmedabad, India. Sephadex G-50 (medium) was procured from M/s Sigma-Aldrich, St. Louis, USA. Span 80 has been procured from Loba Chemie Pvt Ltd, Mumbai, India. Ethanol was purchased from Lobache, Mumbai, India. All the other chemicals used for formulation development were of analytical grade. Double distilled water was used throughout the study.

Garg V., Singh H., Bhatia A., Raza K., Singh S.K., Singh B, & Beg S. (2017). Systematic Development of Transethosomal Gel System of Piroxicam: Formulation Optimization, In Vitro Evaluation, and Ex Vivo Assessment. AAPS PharmSciTech, 18(1).

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