MR scans were acquired using a 7T ClinScan MR-Scanner (Bruker, Ettlingen, Germany) eighteen days after implantation of glioblastoma U87MG-DsRed cells. Animals were anesthetized with a mixture of 1.5% isoflurane (Abbott, Wiesbaden, Germany) evaporated in oxygen at a flow of 0.5 L/min . A dedicated brain coil was used to obtain T2-weighted images of the brain. For the maintenance of the body temperature at 37 °C a heating system connected to a rectal temperature sensor was employed. Image analysis was performed by Inveon Research Workplace 3.1 (Siemens Preclinical Solutions, Erlangen, Germany)
7t clinscan mr scanner
Manufactured by Bruker
Sourced in Germany
The 7T ClinScan MR-Scanner is a high-field magnetic resonance imaging (MRI) system designed for clinical research applications. It operates at a magnetic field strength of 7 Tesla, providing enhanced image resolution and sensitivity compared to lower-field systems. The 7T ClinScan is capable of performing a variety of MRI techniques, including anatomical, functional, and spectroscopic imaging, to support advanced medical research.
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Lab products found in correlation
2 protocols using 7t clinscan mr scanner
1
7T MRI for Glioblastoma Xenograft Monitoring
2
Piglet MRI Contrast Perfusion Protocol
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Preparation of animal: On postnatal day 3, piglets were sedated using Zolteil (Tiletamine/Zolazepam 10 mg/kg intramuscular injection, Virbac, NSW, Australia) and cannulated in the mammary vein (ease of access) using 50 cm of tygon tubing (ID 0.02 inch, OD 0.06 inch) with just the metal needle from a 25G needle on one end and an inserted 25G needle on the other end. Each piglet was then placed in a 300mm bore 7T ClinScan MR scanner (Bruker, Germany), running Siemens VB17. A 150 mm ID MRI rf coil was used to acquire the dynamic images. A syringe was prepared and connected to the cannula containing 1mL Gadovist 1.0 (Bayer) and connected to the cannula.
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