Imaging was performed on a Philips 3T Achieva TX scanner with 16-channel breast coil. The parameters of the FEXI protocol in vivo were: δ=10 ms, Δ=21 ms, tm = 12 (×2), 250 (×2) ms, bf = 0.3 ms/μm2, b = 0.044 (×3), 0.51 (×6) ms/μm2. Here ×2 means that the acquisition was repeated twice with the same parameter, and correspondingly for ×3 and ×6. The values of tm and bf were selected with an optimization minimizing noise propagation, assuming ADC values of 1.3–1.9 μm2/ms (8 ,15 (link)). FEXI was performed with diffusion encoding applied along three orthogonal directions. Seven 5 mm thick slices were acquired using EPI with 3×3 mm spatial resolution, TR = 3 s and total scan time of 6:06 min. Because standard fat suppression did not perform well, we isolated the water and fat signals by chemical shift separation.
3t achieva tx scanner
Manufactured by Philips
Sourced in Netherlands
The Philips 3T Achieva TX scanner is a magnetic resonance imaging (MRI) system that operates at a magnetic field strength of 3 tesla. It is designed to capture high-quality images of the human body for diagnostic and clinical purposes. The core function of the 3T Achieva TX scanner is to generate detailed and accurate visualizations of anatomical structures and physiological processes within the body, providing healthcare professionals with valuable information for medical diagnosis and treatment planning.
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11 protocols using 3t achieva tx scanner
1
Non-Invasive FEXI Imaging Protocol
2
Multimodal Cardiac MRI Acquisition
3
Multimodal MRI protocol for brain imaging
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All participants were scanned on a Philips 3 T achieva TX scanner with an eight-channel head coil. A diffusion tensor image sequence was applied with the following parameters: TR = 7,173 ms, TE = 78 ms, matrix = 115 × 115, FOV = 230 mm × 230 mm, 50 axial slices, b value = 1,000, directions = 32, slice thickness = 3 mm, acquisition time = 9 min 7 sec. A high-resolution 3D TFE sequence was acquired with the following parameters: TR = 7.7 ms, TE = 3.6 ms, matrix = 228 × 228, FOV = 250 mm × 250 mm, 230 axial slices, acquisition time = 6 min 53 sec. In addition, axial T2-weighted MR images were acquired with the parameters: TR = 2,500 ms, TE = 80 ms, matrix = 332 × 225, FOV = 250 mm × 220 mm, slice thickness = 6 mm, 18 axial slices, acquisition time = 55 sec. The anatomical MR images were re-evaluated for any structural abnormalities and were reported as normal in all subjects.
4
Resting-state fMRI Acquisition Protocol
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Functional and anatomical data sets were acquired in a 3T Achieva TX Scanner (Philips Healthcare, Best, the Netherlands) with the use of the eight-channel head coil. To evaluate brain morphology and exclude subjects with brain pathology standard T1 and T2 sequences were applied. No contrast agent was administered. T2* Gradient Echo-Planar Imaging (FFE-EPI: TR, 1,500 ms; TE, 27 ms; flip angle, 60°; matrix, 80 × 80; slice thickness, 3 mm with 0-mm gap, 210 volumes in series; TA 5 min 15 s; FOV, 240 mm × 240 mm), and 3D high-resolution T1 sequence (T1-TFE: TR, 7.44 ms; TE, 3.6 ms; slice thickness, 1 mm; matrix, 260 × 240; FOV, 260 mm × 240 mm) were applied for functional imaging and anatomical reference, respectively. During the resting state, acquisition subjects were asked to consciously attend to the fixation point presented in the center of the visual field and not to think of anything specific. The fixation point was presented via MRI-compatible goggles (NNL fMRI VisualSystem).
5
Multimodal MRI Brain Imaging Protocol
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All participants were scanned on a Philips 3T achieva TX scanner with an eight-channel head coil. A high-resolution 3D TFE sequence was acquired with the following parameters: TR = 7.7 ms, TE = 3.6 ms, matrix = 228 × 228, FOV = 250 mm × 250 mm, 230 axial slices, acquisition time = 6 min 53 s. A diffusion tensor image sequence was applied with the following parameters: TR = 7173 ms, TE = 78 ms, matrix = 115 × 115, FOV = 230 mm × 230 mm, 50 axial slices, slice thickness = 3 mm, diffusion directions = 32, acquisition time = 9 min 7 s. In addition, axial T2-weighted MR images were acquired with the parameters: TR = 2500 ms, TE = 80 ms, matrix = 332 × 225, FOV = 250 mm × 220 mm, slice thickness = 6 mm, 18 axial slices, acquisition time = 55 s. The anatomical MR images were re-evaluated for any structural abnormalities and were reported as normal in all subjects.
6
FEXI Imaging Protocol for Breast MRI
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Imaging was performed on a Philips, Best, The Netherlands 3‐T Achieva TX scanner with a 16‐channel breast coil. The parameters of the FEXI protocol in vivo were as follows: δ = 10 ms; Δ = 21 ms; tm = 12 ms (×2), 250 ms (×2); bf = 0.3 ms/μm2b = 0.044 ms/μm2 (×3), 0.51 ms/μm2 (×6). Here, ‘×2’ means that the acquisition was repeated twice with the same parameter, and correspondingly for ‘×3’ and ‘×6’. The values of tm and bf were selected with an optimization minimizing noise propagation, assuming ADC values of 1.3–1.9 μm2/ms 8 , 15 . FEXI was performed with diffusion encoding applied along three orthogonal directions. Seven 5‐mm‐thick slices were acquired using echo planar imaging (EPI) with 3 × 3‐mm2 spatial resolution, TR = 3 s and a total scan time of 6 min and 6 s. Because standard fat suppression did not perform well, we isolated the water and fat signals by chemical shift separation.
7
Functional MRI Acquisition of Visual Cortex
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Scans were acquired on a Philips 3T Achieva TX scanner, located at the Spinoza Center, Amsterdam, the Netherlands. Whole brain gradient-echo echo-planar imaging (EPI) measurements (voxel size¼3 Â 3 Â 3 mm 3 , repetition time [TR]¼2000 ms, echo time [TE]¼27.63 ms, flip angle ¼76.1°, FOV¼240 Â 240, matrix ¼ 80 Â 80, slice thickness ¼ 3 mm, slice gap ¼0.3 mm, 38 slices per volume, sensitivity encoding factor of 2) were acquired to measure blood oxygen level-dependent (BOLD) magnetic resonance images with a 32-channel SENSE head coil. Scans for the retinotopic mapping runs consisted of partial volume scans (voxel size¼2.5 Â 2.5 Â 2.5 mm 3 , repetition time [TR]¼2000 ms, echo time [TE]¼ 34.53 ms, flip angle [FA] ¼76.1°, FOV¼200 Â 200, matrix¼ 80 Â 80, slice thickness ¼ 2.5 mm, slice gap ¼0.25 mm, 24 slices per volume, sensitivity encoding factor of 2). Two T1weighted anatomical scans were acquired per session (four T1 volumes per participant, voxel size ¼1 Â 1 Â 1 mm 3 , TR¼8229 ms, TE ¼3.77 ms, flip angle ¼8°, FOV¼256 Â 256, matrix ¼256 Â 256, slice thickness ¼ 1 mm, no slice gap, 160 slices per volume). Only one T1-weighted image was used for registration purposes.
8
Functional MRI Acquisition and Processing
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We acquired 306 whole brain T2* weighted echo-planar images (EPI), slice thickness 4mm, 0.3mm gap, 32 axial slices in ascending order, TR 2000ms, TE 30ms, flip angle 80°, matrix 96 x 96, field of view 240mm, on a Philips 3T Achieva TX scanner (Philips Healthcare, Best, The Netherlands) with a 32-channel head coil, housed at Neuroscience Research Australia (Randwick, NSW, Australia). A highresolution T1-weighted anatomical scan (MPRAGE) was also obtained for each participant for registration and screening; TR 8.9ms, TE 4.1ms, field of view 240mm, matrix 268 x 268, 200 sagittal slices, slice thickness 0.9mm (no gap). A radiologist reviewed all scans, and all images were visually inspected to ensure that no gross abnormalities were evident. Image processing and analyses were performed using SPM8 (Wellcome Trust Centre for Neuroimaging, London, UK; http://www.fil.ion.ucl.ac.uk/spm) in Matlab r2011b (Mathworks Inc., Sherborn, MA, USA), and SPM12 for the estimation of cluster extent accounting for multiple comparison correction for F-tests. The pre-processing pipeline is described in Supplementary Material.
9
Rapid Breast DCE-MRI Imaging Protocol
10
Functional MRI Acquisition Protocol for Whole Brain
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Whole brain T2-weighted EPI-BOLD data were acquired with a Philips Achieva 3T TX scanner (Philips Medical Systems, Best, Netherlands) using a 32-channel receiver head coil array. Blood-oxygen-level-dependent (BOLD) fMRI images were generated with a gradient-echo-planar-imaging (EPI) pulse sequence (TR/TE = 2500/30 ms, flip angle = 84°, matrix = 80 × 80, FOV = 240 mm × 240 mm, 44 slices, slice thickness 3 mm, 0.5 mm interslice spacing), that yielded 3 mm × 3 mm × 3 mm voxels. Slices were acquired in descending order and in transverse orientation. Each of the two runs consisted of a total of 335 volumes. Five dummy scans were performed prior to image acquisition aiming to eliminate signals arising from progressive saturation. In addition, a high-resolution T1 anatomic image (TR/TE = 8.1/3.7 ms, flip angle = 8°, matrix 240 × 240, FOV = 240 mm × 240 mm, 160 slices, slice thickness 1.0 mm, 1 mm × 1 mm × 1 mm voxels) was obtained for each subject.
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