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Methacrylic acid anhydride

Manufactured by Merck Group
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Sourced in Germany

Methacrylic acid anhydride is a chemical compound used in the production of various polymers and resins. It serves as a reactant or intermediate in various industrial and laboratory applications.

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Lab products found in correlation

Borate buffer, by Merck Group (1 mentions) Acetone, by Merck Group (1 mentions) Chloroacetyl chloride, by Merck Group (1 mentions) Diethylene glycol, by Merck Group (1 mentions) Magnesium sulfate, by Merck Group (1 mentions) Dichlormethane, by Merck Group (1 mentions) L alanine, by Merck Group (1 mentions) Chloroform, by Merck Group (1 mentions) Sodium hydroxide (naoh), by Merck Group (1 mentions) Phosphate buffered saline (pbs), by Merck Group (1 mentions) Hexane, by Merck Group (1 mentions) Triethylamine, by Merck Group (1 mentions) Ethyl acetate, by Merck Group (1 mentions) Isopropanol, by Merck Group (1 mentions) Diethyl ether, by Merck Group (1 mentions) Heptane, by Merck Group (1 mentions)

2 protocols using methacrylic acid anhydride

1

Synthesis and Purification of HA-MAC

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For HA methacrylate (HA-MAC) synthesis, native HA (MW = 1400 kDa from Streptococcus, Kraeber & Co GmbH, Ellerbek, Germany) was processed as reported before [37 (link)]. In brief, HA was dissolved in borate buffer (pH 8.5, Sigma-Aldrich, Taufkirchen, Germany) and treated with a 15-fold molar excess of methacrylic acid anhydride (Sigma-Aldrich, Taufkirchen, Germany) at 5 °C for 24 h. To purify the product, it was precipitated in acetone (Sigma-Aldrich, Taufkirchen, Germany) and dialyzed against water (MWCO = 3500 g/mol).
Halfter N., Espinosa-Cano E., Pontes-Quero G.M., Ramírez-Jiménez R.A., Heinemann C., Möller S., Schnabelrauch M., Wiesmann H.P., Hintze V, & Aguilar M.R. (2023). Ketoprofen-Based Polymer-Drug Nanoparticles Provide Anti-Inflammatory Properties to HA/Collagen Hydrogels. Journal of Functional Biomaterials, 14(3), 160.
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2

Synthesis and Characterization of Polymeric Biomaterials

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L-Alanine, Chloroacetylchloride, Sodium Hydroxide, Hydrochloric acid Dimethylformamide, Diethylether, Triethylamine, Ethylacetate, Magnesiumsulfate, Chloroform, Isopropanol, Diethylene glycol, Caprolacton, Stannus(II)-Ethylhexonate, Methacrylic acid anhydride, Methacrylic chloride, Dichlormethane, heptane, hexane, acetone, sodium chloride, phosphate buffered saline were purchased from Sigma Aldrich, Taufkirchen, Germany.
Hauptmann N., Ludolph J., Rothe H., Rost J., Krupp A., Lechner J., Kohlhaas S., Winkler M., Stender B., Hildebrand G, & Liefeith K. (2022). Poly-Alanine-ε-Caprolacton-Methacrylate as Scaffold Material with Tuneable Biomechanical Properties for Osteochondral Implants. International Journal of Molecular Sciences, 23(6), 3115.
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