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Cefoperazone sulbactam sodium

Manufactured by Pfizer
Sourced in China

Cefoperazone/sulbactam sodium is a combination antibiotic product. It contains the antibacterial agent cefoperazone and the beta-lactamase inhibitor sulbactam sodium. This product is used in the treatment of various bacterial infections.

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Lab products found in correlation

2 protocols using cefoperazone sulbactam sodium

1

Clinical CRAB Isolates: Antimicrobial Susceptibility

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For this study, eighty-nine non-repeated clinical CRAB strains were collected from patients with CRAB infection between January 2018 and June 2018 in West China Hospital, Sichuan University (a 4300-bed academic tertiary-care hospital). We conducted identification and antimicrobial susceptibility tests (AST) on the VITEK-2 COMPACT automated microbiology system (BioMerieux, France). Species identification was confirmed by detecting and sequencing the gyrB and rpoB genes. The following drugs were used in these experiments: imipenem/cilastatin sodium (Merck Sharp & Dohme Corp., New Jersey, United States), biapenem (Chia Tai Tianqing Pharmaceutical Co., Ltd., Jiangsu, China), cefoperazone/sulbactam sodium (Pfizer, New York, United States), polymyxin B (SPH NO.1 Biochemical & Pharmaceutical Co., Ltd., Shanghai, China), tigecycline (Wyeth Pharmaceutical Co., Ltd., Carolina, United States), and carbonyl cyano-p-chlorphenizone (CCCP) (Sigma-Aldrich, Inc., United States).
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2

Heterotopic Biliary Transplantation in Mice

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At 14 days after the modelling operation, BDD mice were used as donors and recipients. First, the dilated CBD of donor mice was excised, divided into two patches and stored in a histidine-tryptophan-ketoglutarate solution (Custodiol, Koehler Chemi) at 4˚C for transplantation. Second, the dilated CBD of recipient mice was exposed (Fig. 2F). An elliptical incision of ~2x3 mm was made with a microscissor on the ventral side of the CBD (Fig. 2G). The bile was absorbed with a cotton swab. A donor patch was taken and trimmed to be slightly larger than the incision. The patch was first fixed to the CBD at the upper and lower ends with two sutures using two 8-0 nylon threads with needles and then continuous suture was performed from the top to the bottom at one side and from the bottom to the top at the other side of the patch (Fig. 2H). After ensuring no bile leakage, the abdominal cavity was rinsed with normal saline and the abdomen was closed with a 4-0 suture. Antibiotics (cefoperazone sulbactam sodium; Pfizer, Inc.; 60 mg/kg, once per day) were given for 3 days postoperatively and 20% glucose in their drinking water was given for 24 h except for the standard laboratory chow ad libitum (16 (link)).
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