Sigmastat for windows 3

Manufactured by IBM

Sourced in United States

SigmaStat for Windows 3.5 is a software product that provides statistical analysis capabilities. It is designed to run on the Windows 3.5 operating system. The core function of SigmaStat is to perform statistical calculations and generate statistical reports.

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Lab products found in correlation

Calcusyn 2, by Biosoft (3 mentions) Prism 6.04 for windows, by GraphPad (1 mentions) Prism 5, by GraphPad (1 mentions) Prism software, by GraphPad (1 mentions) Prism 6 for windows, by GraphPad (1 mentions)

Close spelling variants of this product

SigmaStat (163 citations) SigmaStat 3.0 (74 citations) SigmaStat for Windows (16 citations) SigmaStat for Windows Version 3.5 (8 citations)

4 protocols using sigmastat for windows 3

Cytotoxicity and Cytoprotective Assays

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In this study, the statistical software SigmaStat for Windows 3.5 (SPSS, CA, USA) was used. Data are presented as mean ± S.D. (standard deviation). Statistical significance was assessed using one-way or two-way ANOVA with a Bonferroni post hoc test (comparisons of multiple groups against corresponding controls). Results were considered to be statistically significant when p < 0.05. The biological half-lives of tested compounds (t_1/2 values); the concentrations of compounds inducing 50 % loss of cellular viability (TC₅₀ values); and the concentrations leading to 50 % protection of cellular viability from toxicity induced by CA (EC₅₀ values) were calculated using the CalcuSyn 2.0 software (Biosoft, U.K.). The graphs were created using GraphPad Prism 6.04 for Windows (GraphPad Software, CA, U.S.A.).

Hašková P., Jansová H., Bureš J., Macháček M., Jirkovská A., Franz K.J., Kovaříková P, & Šimůnek T. (2016). Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury. Toxicology, 371, 17-28.

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Analyzing Compound Toxicity and Protection

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In this study, the statistical software SigmaStat for Windows 3.5 (SPSS, U.S.A.) was used. Data are presented as mean ± SD (standard deviation). Statistical significance was determined using ANOVA with a Bonferroni post hoc test (comparisons of multiple groups against a corresponding control). Results were considered to be statistically significant when p < 0.05. The concentrations of tested compounds inducing 50% toxicity / viability decrease (median toxic concentration; TC₅₀) and the concentration leading to 50% protection from toxicity induced by H₂O₂ (median effective concentration; EC₅₀) were calculated using CalcuSyn 2.0 software (Biosoft, U.K.). The graphs were created using GraphPad Prism 5.04 for Windows.

Jansová H., Macháček M., Wang Q., Hašková P., Jirkovská A., Potůčková E., Kielar F., Franz K.J, & Šimůnek T. (2014). Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. Free radical biology & medicine, 74, 210-221.

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Statistical Analysis Methods

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Statistical analyses were performed using SigmaStat for Windows 3.5 (SPSS, CA, U.S.A.) and GraphPad Prism software, version 5.0 (GraphPad Software, CA, U.S.A). Data were expressed as the mean ± S.D. unless stated otherwise. Statistical significance was determined using Student's t-test or one-way ANOVA with a Bonferroni post-hoc test (comparisons of multiple groups against the corresponding control). The results were considered to be statistically significant when p < 0.05.

Sestak V., Stariat J., Cermanova J., Potuckova E., Chladek J., Roh J., Bures J., Jansova H., Prusa P., Sterba M., Micuda S., Simunek T., Kalinowski D.S., Richardson D.R, & Kovarikova P. (2015). Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents. Oncotarget, 6(40), 42411-42428.

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Cytotoxicity and Cytoprotection Assays

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In this study, the statistical software SigmaStat for Windows 3.5 (SPSS, USA) was used. Data are presented as mean ± SD (standard deviation). Statistical significance was determined using ANOVA with a Bonferroni post hoc test (comparisons of multiple groups against a corresponding control). Results were considered to be statistically significant when p < 0.05. The concentrations of tested compounds inducing 50% toxicity/viability decrease (median toxic concentration; TC₅₀) and the concentration leading to 50% protection from toxicity induced by H₂O₂ (median effective concentration; EC₅₀) were calculated using CalcuSyn 2.0 software (Biosoft, UK). The graphs were created using GraphPad Prism 6 for Windows (GraphPad Software, USA).

Jansová H., Bureš J., Macháček M., Hašková P., Jirkovská A., Roh J., Wang Q., Franz K.J., Kovaříková P, & Šimůnek T. (2016). Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products. Toxicology, 350-352, 15-24.

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