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C57bl 6 b6

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The C57BL/6 (B6) mouse is a widely used inbred laboratory mouse strain. It serves as a common control strain and is often used as a background strain for the creation of genetically modified mouse models.

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Lab products found in correlation

Nod mice, by Taconic Biosciences (1 mentions) Crtac ncr foxn1nu, by Taconic Biosciences (1 mentions) Nod cg prkdcscid il2rgtm1wjl szj nsg mice, by Jackson ImmunoResearch (1 mentions) Balb c mice, by Jackson ImmunoResearch (1 mentions)

4 protocols using c57bl 6 b6

1

Generation of NOD.E2-2fl/fl-CD11c.cre Mice

Cited 1 time
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C57BL/6 (B6) and NOD mice were purchased from Taconic (Ejby, Denmark). B6.E2-2fl/fl-CD11c.cre [23 (link)] were backcrossed to NOD genetic background for >10 generations to generate NOD.E2-2fl/fl-CD11c.cre. SNP-based scans were used to ensure that all chromosomes, except chromosome 18 carrying the E2-2 locus were of NOD origin. By in depth SNP analysis of chromosome 18 we have limited the region flanking the E2-2 locus to <19 cM corresponding to <24 Mb (S1 Table). All animals were bred and maintained in a specific pathogen-free environment at the animal facilities at Umeå University or Lund University and all strains were maintained by continuous inbreeding. Mice were sacrificed by cervical dislocation. Only female mice were used for experiments.
Hansen L., Schmidt-Christensen A., Gupta S., Fransén-Pettersson N., Hannibal T.D., Reizis B., Santamaria P, & Holmberg D. (2015). E2-2 Dependent Plasmacytoid Dendritic Cells Control Autoimmune Diabetes. PLoS ONE, 10(12), e0144090.
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2

Mouse Strains for In Vivo Studies

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A 6-week-old female C57BL/6 (B6) and athymic nude mice (CrTac:NCr-Foxn1nu) were purchased from Taconic Biosciences (Derwood, Maryland, USA). NSG mice (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ) were purchased from the Jackson Laboratory (Bar Harbor, Maine, USA). All mice were maintained under specific pathogen-free conditions at the Johns Hopkins University School of Medicine Animal Facility (Baltimore, Maryland, USA).
Tseng S.H., Park S.T., Lam B., Tsai Y.C., Cheng M.A., Farmer E., Xing D, & Hung C.F. (2020). Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis. Journal for Immunotherapy of Cancer, 8(1), e000480.
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3

Mouse Strain Acquisition and Handling

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C57BL/6 (H-2b) and BALB/c (H-2d) were purchased from the University of Texas Southwestern Mouse Breeding Facility. For grafting experiments, 8- to 10-week-old female BALB/c and C57BL/6 (B6) mice were purchased from Taconic Farms (Germantown, NY, USA). BALB/c D011.10 mice bearing the transgene for the T cell receptor for ovalbumin (OVA) and substance P (SP) knockout (KO) mice on a C57BL/6 background were purchased from The Jackson Laboratories (Bar Harbor, ME, USA). The animal studies were approved by the Institutional Review Board of the University of Texas Southwestern Medical Center. Animals were housed and cared for in accordance with the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research.
Mo J., Neelam S., Mellon J., Brown J.R, & Niederkorn J.Y. (2017). Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens. Investigative Ophthalmology & Visual Science, 58(1), 137-148.
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4

BALB/c and HLA-A2 Transgenic Mice Acquisition

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BALB/c mice at 6 to 8 weeks old were purchased from The Jackson Laboratory (Bar Harbor, ME). HLA-A2-transgenic mice on a C57BL/6 (B6) background were purchased from Taconic (Hudson, NY). Mice were kept in proper conditions as stated in the regulations and guidelines of animal care at the Comparative Bioscience Center animal facility at Rockefeller University.
Coelho-dos-Reis J.G., Huang J., Tsao T., Pereira F.V., Funakoshi R., Nakajima H., Sugiyama H, & Tsuji M. (2016). Co-administration of α-GalCer analog and TLR4 agonist induces robust CD8+ T-cell responses to PyCS protein and WT-1 antigen and activates memory-like effector NKT cells. Clinical immunology (Orlando, Fla.), 168, 6-15.
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