Nt probnp flex reagent cartridge

Manufactured by Siemens

The NT-proBNP Flex Reagent Cartridge is a laboratory equipment product. It is a reagent cartridge designed for the quantitative determination of N-terminal pro-brain natriuretic peptide (NT-proBNP) in human plasma and serum samples using the Siemens healthcare diagnostic systems.

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Lab products found in correlation

Dimension rxl max, by Siemens (2 mentions) Enzymatic assay, by Roche (1 mentions)

Close spelling variants of this product

Flex reagent cartridges (18 citations) NT-proBNP (5 citations)

2 protocols using nt probnp flex reagent cartridge

Fasting Biomarker Measurements in Clinical Study

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Blood samples were drawn in a fasting state and assayed by qualified technicians without the knowledge of the clinical data in a standardized procedure at the central laboratory in the Department of Biochemistry, Chinese People’s Liberation Army General Hospital. Serum NT-proBNP levels were measured with the NT-proBNP Flex Reagent Cartridge, produced by Siemens Healthcare Diagnostics, on the Dimension RXL Max [analytical measuring range (AMR): 10–30,000 pg/mL]. Levels of fasting blood glucose (FBG), cholesterol, high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) were quantified with the Roche enzymatic assays (Roche Products Ltd., Basel, Switzerland) on the Roche autoanalyzer (Roche Products Ltd., Basel, Switzerland). Serum creatinine levels were measured with the enzymatic assay. Glomerular filtration rate (GFR) was calculated with the Chinese modified Modification of Diet in Renal Disease (MDRD) equation: 175 × plasma creatinine ^− 1.234 × age ^− 0.179 × 0.79 (if female) [10 (link)].

Fu S., Jiao J., Guo Y., Zhu B, & Luo L. (2019). N-terminal pro-brain natriuretic peptide levels had an independent and added ability in the evaluation of all-cause mortality in older Chinese patients with atrial fibrillation. BMC Geriatrics, 19, 56.

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Measuring Biomarkers in Chinese Patients

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Blood assays were carried out at the central laboratory in the Department of Biochemistry, Chinese People’s Liberation Army General Hospital. The technicians who performed the tests were blinded to the clinical data of the subjects. Serum NT-proBNP values were measured by the NT-proBNP Flex Reagent Cartridge (PBNP/LPBN), produced by Siemens Healthcare Diagnostics, on the Dimension RXL Max (AMR 10–30,000 pg/mL). Estimated glomerular filtration rate (eGFR) was calculated by a modified Modification of Diet in Renal Disease (MDRD) equation based on data from Chinese patients: 175× serum creatinine (mg/dL)^−1.234 × age (years)^−0.179 ×0.79 (if female).9 (link)

Fu S., Xie L., Li D., Ye P, & Luo L. (2015). The predictive capacity and additional prognostic power of N-terminal pro-B-type natriuretic peptide in Chinese elderly with chronic heart failure. Clinical Interventions in Aging, 10, 359-365.

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