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Brefeldein a

Manufactured by Merck Group
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Brefeldein A is a laboratory reagent produced by Merck Group. It is a chemical compound used in various research and analytical applications. The core function of Brefeldein A is to serve as a tool for researchers and scientists in their experimental work, but a detailed description of its intended use cannot be provided while maintaining an unbiased and factual approach.

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Lab products found in correlation

Staurosporine, by Cayman Chemical (2 mentions) Chloroquine, by Merck Group (2 mentions) Chloropromazine, by Merck Group (2 mentions) Bafilomycin a1, by Merck Group (2 mentions) Methyl β cyclodextrin, by Merck Group (2 mentions) Cytochalasin d, by Merck Group (2 mentions)

2 protocols using brefeldein a

1

Synthesis and Characterization of 1541 Analogs

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Synthesis, purification, and characterization of 1541 and related analogs were made as previously described3 (link). Inhibitors were purchased as following and used as is: brefeldein A (Sigma, B5936, >98%), staurosporine (Cayman chemicals, 81590, >98%), methyl-β-cyclodextrin (Sigma, C4555), cytochalasin D (Sigma, C2618, >98%), chloropromazine (Sigma, C8138, >98%), chloroquine (Sigma, C6628, >98%), and bafilomycin A1 (Sigma, B1793, >90%).
Julien O., Kampmann M., Bassik M.C., Zorn J.A., Venditto V.J., Shimbo K., Agard N.J., Shimada K., Rheingold A.L., Stockwell B.R., Weissman J.S, & Wells J.A. (2014). Unraveling the mechanism of cell death induced by chemical fibrils. Nature chemical biology, 10(11), 969-976.
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2

Synthesis and Characterization of 1541 Analogs

Check if the same lab product or an alternative is used in the 5 most similar protocols
Synthesis, purification, and characterization of 1541 and related analogs were made as previously described3 (link). Inhibitors were purchased as following and used as is: brefeldein A (Sigma, B5936, >98%), staurosporine (Cayman chemicals, 81590, >98%), methyl-β-cyclodextrin (Sigma, C4555), cytochalasin D (Sigma, C2618, >98%), chloropromazine (Sigma, C8138, >98%), chloroquine (Sigma, C6628, >98%), and bafilomycin A1 (Sigma, B1793, >90%).
Julien O., Kampmann M., Bassik M.C., Zorn J.A., Venditto V.J., Shimbo K., Agard N.J., Shimada K., Rheingold A.L., Stockwell B.R., Weissman J.S, & Wells J.A. (2014). Unraveling the mechanism of cell death induced by chemical fibrils. Nature chemical biology, 10(11), 969-976.
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