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Anti cd4 okt4

Manufactured by BioXCell

The Anti-CD4 (OKT4) is a monoclonal antibody that binds to the CD4 receptor on T cells. It is a laboratory tool used for the identification and analysis of CD4+ T cell populations.

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2 protocols using anti cd4 okt4

1

Anti-CD4/CD8 Tumor Immunotherapy in Mice

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Mice were injected intra-peritoneally with 200 μg of anti-CD4 (OKT4; BioXcell) and/or 200 μg anti-CD8 (OKT8; BioXcell) monoclonal antibodies at days −2, −1, 0, +1, +6, and +14 relative to Raji tumor implantation. Control mice were given 200 μg mouse IgG2b and/or mouse IgG2a isotype control at same time as anti-CD4 and/or anti-CD8 treatment. Tumor growth was measured then as described above.
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2

SARS-CoV-2 Infection Kinetics in Antibody-Depleted Mice

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BLT-L mice were administered 200 mg of anti-CD3e (OKT3) (BioxCell; cat. # BE0001–2), anti-CD4 (OKT4) (BioxCell; cat. # BE0003–2), anti-CD8 (OKT8) (BioxCell; cat. # BE0004–2), or isotype IgG2a (Thermofisher; cat # 02–6200) antibody 3-, 2-, and 1-day prior to inoculation and 4- and 8-days post inoculation with 1×106 PFU SARS-CoV-2 WA-1.
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