10-HCPT, and EDCI (1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide) were obtained from Sigma Chemical Co. (St Louis, MO, USA). 5-Carbonyl caproic acid and dichloromethane were obtained from Shanghai Topbiochem Ltd. (Shanghai, People's Republic of China). Anhydrous N,N-dimethylformamide (DMF), thiosemicarbazide, and sulfoxide chloride were obtained from Aladdin Industrial Corporation (Shanghai, People's Republic of China). MeO-PEG2000-COOH (molecular weight 2,000 Da) was obtained from Xi'an Ruixi Biological Technology Co. Ltd. (Xi'an, People's Republic of China). Sephadex LH-20 was obtained from Shanghai Yuanye Bio-Technology Co. Ltd. (Shanghai, People's Republic of China). All other chemicals were of analytical grade and were used without further purification.
Meo peg2000 cooh
Manufactured by Xi’an Ruixi
MeO-PEG2000-COOH is a polyethylene glycol (PEG) derivative with a carboxyl functional group. It has a molecular weight of approximately 2,000 Daltons. This compound is commonly used in various biomedical and pharmaceutical applications as a linker or coupling agent.
Automatically generated - may contain errors
2 protocols using meo peg2000 cooh
1
Synthesis of PEGylated 10-HCPT Conjugate
2
Synthesis and Characterization of PEG-Conjugated HCPT Prodrug
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10-HCPT, EDCI (1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide), and MTT (methylthiazolyldiphenyl-tetrazolium bromide) were obtained from Sigma Chemical Co. (St Louis, MO, USA). 5-carbonyl caproic acid and dichloromethane were obtained from Shanghai Topbiochem Ltd. (Shanghai, People’s Republic of China). Anhydrous N,N-dimethylformamide (DMF), thiosemicarbazide, and sulfoxide chloride were obtained from Aladdin Industrial Corporation (Shanghai, People’s Republic of China). MeO-PEG2000–COOH (molecular weight ~2,000 Da) was obtained from Xi’an Ruixi Biological Technology Co. Ltd. (Xi’an, People’s Republic of China). Sephadex LH-20 was obtained from Shanghai Yuanye Bio-Technology Co. Ltd. (Shanghai, People’s Republic of China). All other chemicals were of analytical grade and were used without further purification.
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