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Triamcinolone

Manufactured by Alcon
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Sourced in United States, India

Triamcinolone is a synthetic corticosteroid medication used in laboratory settings. It is a crystalline compound with anti-inflammatory properties. Triamcinolone is commonly used in research applications, but its specific function and intended use should not be interpreted or extrapolated in this context.

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Lab products found in correlation

Constellation vision system, by Alcon (2 mentions) Pred forte, by Abbvie (1 mentions) Vigamox, by Alcon (1 mentions) Moxifloxacin, by Alcon (1 mentions) End gripping forceps, by Alcon (1 mentions)

3 protocols using triamcinolone

1

Posterior Vitreous Separation and ILM Peeling

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25G PPV was performed using the CONSTELLATION Vision System (Alcon Laboratories, Inc.). In all eyes, a central vitrectomy was performed. The posterior vitreous was separated from the retina by active aspiration with the vitrectomy probe, and any visible vitreous strands that were adherent to the retina were removed. Intravitreous triamcinolone (40 mg/mL, Triesence®, Alcon, Forth Worth, Texas, USA) was systematically used in all cases as a marker to facilitate visualization and removal of the adherent posterior cortical vitreous. triamcinolone was fully washed out before performance of ILM-peeling in all cases. ILM-peeling was systematically performed using vision blue G (0,125 mg Brilliant Blue G, Fluoron, Ulm, Germany) to stain and then remove the ILM. Postoperatively, topical antibiotic (Vigamox, moxifloxacin 0.5%, Alcon, USA) and antiinflammatory therapy (Pred Forte, prednisolone acetonide 1%, Allergan, Ireland) were administered 4 times daily over 1 month.
Iglicki M., Lavaque A., Ozimek M., Negri H.P., Okada M., Chhablani J., Busch C., Loewenstein A, & Zur D. (2018). Biomarkers and predictors for functional and anatomic outcomes for small gauge pars plana vitrectomy and peeling of the internal limiting membrane in naïve diabetic macular edema: The VITAL Study. PLoS ONE, 13(7), e0200365.
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2

Transconjunctival Sutureless Vitrectomy

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The surgeries were performed by 5 surgeons (P.K., D.P., J.C., N.W., and V.C.) with more than 10 years of experience in vitreoretinal surgery. A 3-port 23-gauge transconjunctival sutureless vitrectomy was performed using the CONSTELLATION Vision System (Alcon Laboratories, Inc, Fort Worth, Texas, USA). In all eyes, a central vitrectomy was performed and the posterior vitreous humor was separated from the retina. After vitrectomy the ERM and internal limiting membrane were removed using end-gripping forceps (Alcon, Fort Worth, TX, USA) with the assistance of Brilliant Blue G dye (0.05% w/v, Aurolab, India) or triamcinolone (40 mg/mL, Triesence; Alcon, Fort Worth, Texas, USA). The ERM and internal limiting membrane were removed from the central macular area up to the arcades.
Kunavisarut P., Supawongwattana M., Patikulsila D., Choovuthayakorn J., Watanachai N., Chaikitmongkol V., Pathanapitoon K, & Rothova A. (2022). Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors. Turkish Journal of Ophthalmology, 52(2), 109-118.
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3

Quantifying Corneal Contrast Enhancement

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Quantitative image analysis was performed on fresh cadaveric porcine eyes following application of three contrast agents [ICG, triamcinolone (Triesence, Alcon, Fort Worth, TX), and 1% prednisolone acetate]. Imaging was performed with a portable spectral domain OCT system (Bioptigen). All procedures were performed in triplicate. A fresh porcine eye was initially imaged without contrast (e.g., artificial tears) and then imaged after 1-2 drops of contrast solution was placed on the cornea surface. Intracorneal measurements were also performed. A 2.8 mm keratome clear-corneal incision was made in the peripheral cornea and imaged without contrast material. The clear corneal incision was then stained with the contrast agent and imaged. Contrast enhancement was evaluated at various planes including on the corneal surface (topical) and within the corneal wound (intracorneal). OCT contrast ratio was calculated as outlined above
Ehlers J.P., McNutt S., Dar S., Tao Y.K, & Srivastava S.K. (2014). Visualization of Contrast-Enhanced Intraoperative Optical Coherence Tomography with Indocyanine Green. The British journal of ophthalmology, 98(11), 1588-1591.
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