Signa excite 3.0 tesla

Manufactured by GE Healthcare

The Signa Excite 3.0 Tesla is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It operates at a magnetic field strength of 3.0 Tesla, providing high-quality imaging capabilities. The core function of the Signa Excite 3.0 Tesla is to generate detailed images of the body's internal structures for diagnostic purposes.

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Lab products found in correlation

Mr750 3.0 tesla scanner, by GE Healthcare (1 mentions)

Spelling variants of this product

Signa Excite (231 citations) 3.0 Tesla (6 citations) SIGNA 3.0 tesla (3 citations) Signa EXCITE 3.0 Tesla MR imaging system (2 citations)

6 protocols using signa excite 3.0 tesla

Multimodal Brain Imaging Protocol

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At study entry participants underwent anatomical and DTI scans. Images were acquired on a General Electric (Waukesha, WI) Signa Excite 3.0 Tesla short bore scanner at Froedtert Memorial Lutheran Hospital (Milwaukee, WI). Foam padding was used to reduce head movement within the coil.

Lancaster M.A., Seidenberg M., Smith J.C., Nielson K.A., Woodard J.L., Durgerian S, & Rao S.M. (2016). Diffusion Tensor Imaging Predictors of Episodic Memory Decline in Healthy Elders at Genetic Risk for Alzheimer’s Disease. Journal of the International Neuropsychological Society : JINS, 22(10), 1005-1015.

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Functional MRI with Distortion Correction

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Participants were scanned at the UCSD Keck Center for fMRI using a GE Signa EXCITE 3.0 Tesla whole-body imaging system. Anatomical scans utilized a T1-weighted fast spoiled gradient echo pulse sequence (TE=4ms, flip angle= 90°, 1mm³ resolution). The functional scans were sensitive to the T2*-weighted BOLD signal. 32 echoplanar 4mm axial slices covering the whole brain (TR=2000 ms, TE=30 ms, image matrix=64×64, 4mm × 4mm resolution) were acquired parallel to the intercommissural plane in an interleaved manner using a gradient echo pulse sequence. The number of repetitions acquired varied over the task, as described above. To correct for warping in the echo-planar images due to inhomogeneties in the magnetic field, scans with opposite phase encoding polarities resulting in opposite spatial distortion patterns were acquired. The resulting images were aligned using a fast nonlinear registration procedure (Holland et al., 2010 (link)).

McKenna B.S., Drummond S.P, & Eyler L.T. (2014). Associations between Circadian Activity Rhythms and Functional Brain Abnormalities among Euthymic Bipolar Patients: A Preliminary Study. Journal of affective disorders, 164, 101-106.

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Hippocampal Subfield Volumetry in MCI Conversion

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High-resolution, three-dimensional spoiled gradient-recalled at steady-state (SPGR) anatomic images were acquired on a General Electric (Waukesha, WI) Signa Excite 3.0 Tesla short bore scanner equipped with a quad split quadrature transmit/receive head coil (TE = 3.9 ms; TR = 9.5 ms; inversion recovery (IR) preparation time = 450 ms; flip angle = 12°; number of excitations (NEX) = 1; slice thickness = 1.0 mm; FOV = 24 cm; resolution = 256×224). Whole brain and regional volumes were derived from T1-weighted SPGR images using Freesurfer v.6.0 software hippocampal subfields algorithm (Iglesias et al., 2015 (link)). Intracranial volume was corrected using the Freesurfer estimate of TIV (%TIV). Hippocampcal measures as defined by Freesurfer 6.0 subfield segmentation were selected a priori to assess differences in volumes between ε4+ MCI converters and ε4+ non-converters (bilateral whole hippocampus and subiculum).

Abraham M., Seidenberg M., Kelly D.A., Nielson K.A., Woodard J.L., Smith J.C., Durgerian S, & Rao S.M. (2020). Episodic Memory and Hippocampal Volume Predict Five-Year MCI Conversion in Healthy APOE ε4 Carriers. Journal of the International Neuropsychological Society : JINS, 26(7), 733-738.

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3T MRI brain morphometry protocol

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High-resolution, three-dimensional spoiled gradient-recalled at steady-state (SPGR) anatomic images were acquired on a General Electric (Waukesha, WI) Signa Excite 3.0 Tesla short bore scanner equipped with a quad split quadrature transmit/receive head coil (TE = 3.9 ms; TR = 9.5 ms; inversion recovery (IR) preparation time = 450 ms; flip angle = 12°; number of excitations (NEX) = 2; slice thickness = 1.0 mm; FOV = 24 cm; resolution = 256 × 224). A scanner upgrade took place near the end of the final retest period. Six ε4+ participants and one ε4- had their third scan conducted on a GE MR750 3.0 Tesla scanner (TE = 3.9 ms; TR = 9.6 ms; inversion recovery (IR) preparation time = 450 ms; flip angle = 12°; number of excitations (NEX)=1; slice thickness = 1.0 mm; FOV = 24 cm; resolution=256×224). A between-scanner comparison showed no systematic differences. Whole brain and regional volumes were derived from T1- weighted SPGR images using the longitudinal stream in Freesurfer v.5.1 software [23 (link)].

Reiter K., Nielson K.A., Durgerian S., Woodard J.L., Smith J.C., Seidenberg M., Kelly D.A, & Rao S.M. (2017). Five-year longitudinal brain volume change in healthy elders at genetic risk for Alzheimer’s disease. Journal of Alzheimer's disease : JAD, 55(4), 1363-1377.

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3T MRI Brain Imaging Protocol

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DTI and high-resolution anatomical images were collected on a General Electric (Waukesha, WI) Signa Excite 3.0 Tesla short bore scanner at Froedtert Hospital (Milwaukee, WI). Foam padding was used to reduce head movement within the coil. High-resolution anatomical scans were obtained from a three-dimensional spoiled gradient-recalled at steady-state (SPGR) pulse sequence (TE = 3.9 ms; TR = 9.5 ms; inversion recovery (IR) preparation time = 450 ms; flip angle = 12 degrees; number of excitations (NEX) = 2; slice thickness = 1.0 mm; field of view (FOV) = 24 cm; resolution = 256 × 224; slices = 144).

Smith J.C., Lancaster M.A., Nielson K.A., Woodard J.L., Seidenberg M., Durgerian S., Sakaie K, & Rao S.M. (2015). Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders. NeuroImage, 131, 102-112.

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Functional MRI of Brain Anatomy

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Magnetic resonance images were collected in General Electric Signa Excite 3.0
Tesla short bore MR Scanner (GE Healthcare, Waukesha, WI). Functional MRI was used to
quantify the BOLD contrast (T2*-weighted imaging) overlaid on a T1-weighted anatomical
image for each subject. An 8-channel array radio frequency receive head coil (GE
Healthcare, Waukesha, WI) was used to obtain 36 sagittal plane slices (thickness = 4 mm)
across the entire brain volume using an echo-planar imaging sequence (64 × 64
matrix, 240 × 240 mm² field of view, TE = 25 ms, TR = 2,000 ms, and
flip angle = 77°). Voxel size was 3.75 × 3.75 × 4 mm. Immediately
after completion of the protocol, 148 high-resolution spoiled GRASS (gradient recalled at
steady state) anatomical images (thickness = 1 mm) were collected (256 × 244
matrix, TE = 3.9 ms, TR = 9.5 ms, and flip angle = 12°).

Yoon T., Vanden Noven M.L., Nielson K.A, & Hunter S.K. (2014). Brain areas associated with force steadiness and intensity during isometric ankle dorsiflexion in men and women. Experimental brain research, 232(10), 3133-3145.

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