Nomo 1

AML-derived THP-1 and KG-1a cells were purchased from RIKEN biological resource center (BRC, Japan). AML-derived Kasumi-1, HL60, SKNO-1, NOMO-1 cells and embryonic kidney derived HEK293T cells were from Japanese Collection of Research Bioresources (JCRB, Japan). AML-derived KO52, NB4, ME-1, ML-2, OCI-AML2, MV4-11, MOLM-13 and HEL cells were purchased from Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ, Germany). HEK293T cells were maintained in Dulbecco's modified Eagle’s medium (DMEM) supplemented with 10% heat-inactivated fetal bovine serum (FBS) and 1% Penicillin–Streptomycin (PS) in a humidified incubator with 5% CO2 and 95% air at 37 °C. The other cells were cultured in Roswell Park Memorial Institute (RPMI) 1640 medium containing 10% FBS and 1% PS under 5% CO₂ and 95% air at 37 °C.

T cell non-Hodgkin’s lymphoma cell line KARPAS299 was supplied by the European Collection of Authenticated Cell Cultures (ECACC). Multiple myeloma cell lines, MM.1S and RPMI8226; Burkitt’s lymphoma cell lines, Daudi, Raji, and NAMALWA; the acute myelogenous leukemia cell line, KG1; the acute T cell leukemia cell line, Jurkat; and the chronic myelogenous leukemia cell line, K562, were supplied by American Type Culture Collection (ATCC). Acute monocytic leukemia cell lines, THP-1, MOLM-13, and NOMO-1; and the myelodysplastic syndrome cell line, SKM-1, were supplied by Japanese Collection of Research Bioresources Cell Bank (JCRB). All these cell lines were maintained in RPMI 1640 (Gibco BRL) supplemented with 10% heat-inactivated fetal bovine serum (Sigma), 100 µg/mL streptomycin, and 100 U/mL penicillin.