B6 cg tg vil cre 1000gum j mice

C57BL/6 (WT B6, H-2K^b, CD45.2), B6 Ly5.2 (H-2K^b, CD45.1), B6.129S7-Rag1^tm1Mom/J(Rag-1^−/−), Sdhaf1^−/−, B6.Cg-Tg(ACTFLPe)9205Dym/J, B6.Cg-Tg(Vil-cre)1000Gum/J mice, C3H.SW (H-2K^b, CD229.1), and C57BL/6N-Acod1em1(IMPC)J/J (Irg1^−/−) mice were purchased from the Jackson Laboratory (Bar Harbor, ME, USA). BALB/c (H-2K^d) and BDF1 (H-2K^b/d) mice were purchased from Charles River Laboratories. C57BL/6N-Sdha^{tm2a(KOMP)Wtsi} mice were obtained from Knock Out Mouse Project (KOMP) repository, University of California, Davis and bred to ACTFLPe mice to excise the FRT-flanked region (Extended Data Figure 6g). Then Sdha^fl/fl mice were bred to Vil1-Cre mice to create Vil1-Cre Sdha^fl/fl (Sdha^Δ/IEC) mice. 8–12 weeks old female mice used for experiments. All mice were kept under specific pathogen-free (SPF) conditions and cared for according to regulations reviewed and approved by the University of Michigan Committee on the Use and Care of Animals (PRO00009494), which are based on the University of Michigan Laboratory Animal Medicine guidelines