It was calculated that 18 subjects needed to be included in this study to have a power of 80% with a P < 0.017 (to account for multiple comparisons between groups) to detect a change of 0.15 ng/mL in plasma 7β-OH-campesterol concentrations with a within-subject variation of 0.14 ng/mL. Since the expected dropout rate was 10%, 20 men and women were included in the study. A Shapiro-Wilk test for normality was performed to assess whether parameters followed a normal distribution. Effects of vitamin E or lipoic acid supplementation were evaluated by a univariate analysis of variance (ANOVA) with subject number as a random factor for normally distributed data. Differences in oxyphytosterol and oxycholesterol levels in RBC, PBMC and blood platelet fractions were evaluated by Friedman’s test for not normally distributed data and reported as medians with ranges. Oxyphytosterol concentrations in healthy subjects were measured in our previous study using exactly the same method4 (link) and compared to the current population of IGT and diabetic subjects by a Mann-Whitney U test. All statistical analyses were performed two-sided using SPSS 20.0 for Mac Os X and adjusted by Bonferroni’s correction for multiple comparisons or by post-hoc analysis for Friedman’s test when appropriate (SPSS Inc., Chicago, IL, USA).
Spss 20.0 for mac os x
Manufactured by IBM
Sourced in United States
SPSS 20.0 for Mac OS X is a statistical software package designed for data analysis. It provides tools for data manipulation, statistical modeling, and visualization. The software is compatible with the Mac OS X operating system.
Automatically generated - may contain errors
Lab products found in correlation
3 protocols using spss 20.0 for mac os x
1
Oxyphytosterol Levels in IGT and Diabetes
2
Validated Patient-Reported Outcome Measure
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Measurement data were expressed by mean±standard deviation. The Shapiro-Wilk normality test was first performed to check for normal distributions. Sample size estimation was done in G*Power software (Germany) based on the AOFAS scores in a previous study [17 (link)]. Allocation of the 108 patients was calculated to provide 90% power (actual power 0.953) to test the hypothesis regarding the validated patient-reported outcome measure (AOFAS). The 95% confidence interval (a type-I error rate of 0.05) was used to analyze whether there was a difference in the AOFAS. Ten-point differences in the AOFAS [18 (link)] were recorded as the minimal clinically important change score (MCID), and the estimated dropout rate was 15%. We included 120 patients in the study and 108 patients completed the final follow-up. SPSS 20.0 for Mac OSX (SPSS, Inc, Chicago, IL, USA) was used for statistical processing and one-way analysis of variance or the t test was used. The chi-square test was used for count data. P<0.05 indicated statistically significant differences.
3
Effects of NWT-03 on Blood Pressure
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A Shapiro-Wilk test was used to evaluate whether the data were normally distributed. Independent samples t tests were used to check for carryover effects between the NWT-03 and placebo periods. Comparisons between the effects of 1, 2 and 5 g NWT-03 and placebo on daytime BP, night-time BP, 36-h BP, percentage decline in nocturnal BP and 36-h BP variability were made using paired samples t tests for all subjects combined and for the three BP categories separately. Data are expressed as mean values and standard deviations. All statistical tests were performed two-sided at 5 % level of significance using SPSS 20.0 for Mac OS X (SPSS Inc.).
It was calculated that a sample size of twenty-eight subjects per treatment group (1, 2 and 5 g NWT-03) was needed to show an effect size of 7 mmHg in daytime SBP with a power of 80 % with an SD of the response of 9 mmHg (12, 13) and an α of 0•05 (two-tailed).
It was calculated that a sample size of twenty-eight subjects per treatment group (1, 2 and 5 g NWT-03) was needed to show an effect size of 7 mmHg in daytime SBP with a power of 80 % with an SD of the response of 9 mmHg (12, 13) and an α of 0•05 (two-tailed).
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