All patients had a planning CT scan acquired using a Lightspeed Ultra 8 scanner (GE Medical Systems, Chicago, IL, USA). RT planning was done in Oncentra ® (External Beam, Elekta, Sweden). For each patient, volumes of interest (VOIs) such as gross tumor volume (GTV), total body of vertebral column, lungs, and patients’ outer contour were delineated in the planning CT images. In order to acquire thoracic VOI, a CT window of −500 to 1200 Hounsfield Units on patients’ outer contour was applied in the planning CT to include thoracic soft tissue and trabecular bone. Various RT dose parameters such as V10 (percentage of VOI receiving 10 Gy or more), V15, V20, and mean dose to the VOIs were calculated. RT data extraction have been done in IDL (Interactive Data Language, v 8.6, Research Systems, Boulder, CO, USA) as described previously [21] (link).
Lightspeed ultra 8
Manufactured by GE Healthcare
Sourced in United States
The Lightspeed Ultra 8 is a computed tomography (CT) imaging system developed by GE Healthcare. It is designed to capture high-quality images of the body's internal structures. The system utilizes advanced X-ray technology to generate detailed, three-dimensional representations of the scanned area.
Automatically generated - may contain errors
Lab products found in correlation
Lightspeed vct, by GE Healthcare (1 mentions)
Brilliance 40, by Philips (1 mentions)
Lightspeed qx i, by GE Healthcare (1 mentions)
Lightspeed ultra 16, by GE Healthcare (1 mentions)
Brilliance ct 64, by Philips (1 mentions)
Somatom sensation 16, by Siemens (1 mentions)
Somatom definition, by Siemens (1 mentions)
4 protocols using lightspeed ultra 8
1
Radiotherapy Dose Parameters Extraction
2
Kidney CT Imaging Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
CT scans were performed by using one of five multidetector units (LightSpeed QX/I, LightSpeed Ultra8, LightSpeed Ultra16, and LightSpeed VCT, GE Medical System, Milwaukee, Wis; Brilliance 40, Philips Medical Systems, Cleveland, Ohio). The parameters for the unenhanced and contrast-enhanced examinations included 0.625–5 mm collimation, pitch of 0.750–0.984, reconstructed section thickness of 3–5 mm, 120 kVp, and 180–240 mAs[11 (link)]. Contrast-enhanced CT scans were obtained after intravenous injection of 120 ml of nonionic contrast medium at a rate of 2.5–3.0 ml/sec by using a power injector. The kidney CT protocol included an unenhanced CT and two-phase contrast-enhanced CT in which images were obtained 30 seconds (arterial phase) and 3 minutes (venous phase) after bolus contrast material injection.
3
Quantitative CT Analysis of Emphysema
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All patients underwent a CT scan (Light Speed Ultra 8, General Electric, Boston, MA, USA) for target lobe selection and emphysema evaluation at baseline and for follow-up around 3 months after endoscopic valve implantation. The CT protocol was identical for all scans and included a slice thickness of 1.25 mm, 120 kVp, and 100 mAs. The scans were obtained in deep inspiration without intravenous contrast medium administration. We retrospectively performed quantitative analysis of the chest CT scans using the MeVisPULMO 3D software, version 3.42 (Fraunhofer MEVIS, Bremen, Germany), which enables quantification of emphysematous lung parenchyma by determining the emphysema score defined as the ratio of voxels with a density below a certain threshold to the total number of voxels in the region of interest.19 We chose a threshold of −950 HU as proposed in previous studies.20 –22 Furthermore, we used the software for semiautomatic segmentation of the lung into the lung lobes (left upper lobe, left lower lobe, right upper lobe, right middle lobe, and right lower lobe) as described in the literature.19 ,23 See also example in Figure 1 .
4
Measuring Kidney Volume via CT Imaging
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Of 233 patients, 200 patients underwent CT within 1 year from their enrollment time points. Thirty-three patients were excluded from the analysis because they underwent CT scans apart from urinary biomarker measurement (>1 year). Among them, 189 patients had available height information to calculate htTKV (mL/m) [21 (link)]. We have calculated TKV from 3- to 5-mm thickness three-dimensional contrast-enhanced CT of the kidney and bladder using a multi-detector CT scanner (Somatom Sensation 16, SIEMENS; Light speed Ultra 8, GE; Brilliance CT 64, Philips; Somatom Definition, SIEMENS). The CT examination was performed either with contrast agent or without depending on patient’s renal function. In order to acquire contrast images, we administered contrast material right after pre-contrast image acquisition and acquire post-contrast images about 17-20 s later when the Hounsfield Unit (HU) at the descending aorta reaches 100HU. The htTKV was defined as the sum of the left and right renal volumes divided by height of the patient.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!