Naproxen npx

Manufactured by Merck Group

Sourced in Germany, United States, United Kingdom

Naproxen (NPX) is a non-steroidal anti-inflammatory drug (NSAID) used as a laboratory standard for research and development purposes. It is a crystalline solid with a chemical formula of C14H14O3. Naproxen is commonly utilized in analytical procedures, formulation development, and stability studies involving pharmaceutical products.

Automatically generated - may contain errors

Lab products found in correlation

Spelling variants of this product

Naproxen (105 citations)

4 protocols using naproxen npx

Preparation of Stimulus-Responsive Polymer Particles

Check if the same lab product or an alternative is used in the 5 most similar protocols

All reagents, methacrylic acid (MAA), 2-vinylpyridine (2-VP), ethylene glycol dimethacrylate (EDGMA), azobisisobutyronitrile (AIBN), polyvinyl alcohol (PVA), lauryl sulfate (SDS), formic acid, diclofenac (DCF) sodium, and naproxen (NPX) were purchased from Sigma-Aldrich (Darmstadt, Germany). The organic solvents, methanol, and toluene were obtained from Tedia Company Inc. (Fairfield, Ohio, USA). Hydrochloric acid (HCl) and potassium hydroxide (KOH) were supplied by Merck (State of Mexico).

Meléndez-Marmolejo J., Díaz de León-Martínez L., Galván-Romero V., Villarreal-Lucio S., Ocampo-Pérez R., Medellín-Castillo N.A., Padilla-Ortega E., Rodríguez-Torres I, & Flores-Ramírez R. (2022). Design and application of molecularly imprinted polymers for adsorption and environmental assessment of anti-inflammatory drugs in wastewater samples. Environmental Science and Pollution Research International, 29(30), 45885-45902.

+ Open protocol

+ Expand

Peptide Conjugation Using PEG Linker

Check if the same lab product or an alternative is used in the 5 most similar protocols

Ethyl acetate, n-hexane, tetrahydrofuran (THF), diethyl ether, N,N‐dimethylformamide (DMF, anhydrous), l-alanine, l-isoleucine, bis(trichloromethyl) carbonate, glycine, trichloromethyl chloroformate, Proteinase K, Trypsin and naproxen (Npx) were purchased from Sigma-Aldrich (USA). Monomethoxy-monoamino-terminated poly(ethylene glycol) (mPEG₄₅-NH₂, M_n = 2000 g/mol) was purchased from Rapp Polymere (Germany). All chemicals were used without further purification, unless otherwise noted. Nanopure water (18.2 MΩ•cm) was acquired from a Milli-Q water filtration system, Millipore Corp. (St. Charles, MO). Tris-HCl buffered saline and phosphate buffered saline (PBS) were purchased from Sigma-Aldrich (USA) as dry powders, and dissolved in deionized water (1.0 L) to obtain the desired buffer solutions.

Fan J., Li R., Wang H., He X., Nguyen T.P., Letteri R.A., Zou J, & Wooley K.L. (2017). Multi-responsive polypeptide hydrogels derived from N–carboxyanhydride terpolymerizations for delivery of nonsteroidal anti-inflammatory drugs (NSAIDs). Organic & biomolecular chemistry, 15(24), 5145-5154.

+ Open protocol

+ Expand

Polymer-drug Physicochemical Characterization

Check if the same lab product or an alternative is used in the 5 most similar protocols

Indomethacin (IND), naproxen (NPX) and ibuprofen (IBU) with a purity of 99% were purchased from Sigma Aldrich (Irvine, UK) and Kemprotec (Kent, UK).
Polymer Eudragit® E (EPO) is a cationic copolymer based on dimethylaminoethyl methacrylate, butyl methacrylate, and methyl methacrylate with a ratio of 2:1:1, was generously donated by Evonik GmbH (Darmstadt, Germany). The chemical structures of the polymer and drugs are shown in Figure 1 and the physicochemical properties of these substances used in this study are summarised in Table 1.

Tian Y., Jacobs E., Jones D.S., McCoy C.P., Wu H, & Andrews G.P. (2020). The design and development of high drug loading amorphous solid dispersion for hot-melt extrusion platform. International journal of pharmaceutics, 586.

+ Open protocol

+ Expand

Characterization of Functionalized Carbon Nanotubes

Check if the same lab product or an alternative is used in the 5 most similar protocols

Naproxen (NPX) was purchased from Sigma-Aldrich with a purity ≥ 98%. All reactants used in the buffer solutions were from Sigma-Aldrich and in analytical grade. Phosphate buffer (PBS) solutions were prepared by mixing the corresponding amount of sodium chloride (NaCl), potassium chloride (KCl), potassium phosphate monobasic (KH2PO4) and sodium phosphate dibasic (Na2HPO4).
Three different MWCNT manufactured by DropSense have been checked: non-functionalized MWCNT, MWCNT functionalized with -COOH groups (MWCNT-COOH) and with -NH2 groups (MWCNT-NH2), whose main properties were determined in previous works (Patiño et al. 2017; Patiño et al. 2018) .

Díaz E., Stożek S., Patiño Y, & Ordóñez S. (2019). Electrochemical degradation of naproxen from water by anodic oxidation with multiwall carbon nanotubes glassy carbon electrode. Water science and technology : a journal of the International Association on Water Pollution Research, 79(3).

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!