Anti aβ

Manufactured by Cell Signaling Technology

Anti-Aβ is a laboratory reagent used to detect and study amyloid-beta (Aβ) proteins. Aβ is a key component in the development of Alzheimer's disease. Anti-Aβ can be used to identify and quantify Aβ in various biological samples.

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Lab products found in correlation

Vector vip chromogen, by Vector Laboratories (1 mentions) Anti p70s6k, by Cell Signaling Technology (1 mentions) Anti v5, by Thermo Fisher Scientific (1 mentions) Anti phospho p70s6k, by Cell Signaling Technology (1 mentions) Anti phospho mtor, by Cell Signaling Technology (1 mentions) Anti lamp1, by Abcam (1 mentions) Anti α synuclein, by Abcam (1 mentions) Anti rab7, by Santa Cruz Biotechnology (1 mentions) Anti rab5, by Abcam (1 mentions) Anti v5 hrp, by Merck Group (1 mentions) Anti app n terminal 22c11, by Merck Group (1 mentions) Anti his tag, by Merck Group (1 mentions) Anti phosho erk1 2, by Cell Signaling Technology (1 mentions) Anti golgi 58k, by Merck Group (1 mentions) Anti tgn46, by Abcam (1 mentions) Anti mtor, by Cell Signaling Technology (1 mentions) Anti calnexin, by Merck Group (1 mentions) Anti erk1 2, by Cell Signaling Technology (1 mentions) Anti phospho creb, by Cell Signaling Technology (1 mentions) Anti β actin, by Merck Group (1 mentions)

Close spelling variants of this product

Mouse anti-Aβ (4 citations) Rabbit anti-Aβ (3 citations)

3 protocols using anti aβ

Submandibular Gland Immunohistochemistry for AD

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Paraffin-embedded submandibular gland tissue sections (10μm) from 5 male and 5 female AD and similar age controls were obtained from Banner Health (Sun City, AZ). The tissue was immunostained with anti-APP (Y188), anti-Aβ (Cell Signaling) or respective secondary only antibodies. Slides were antigen retrieved in 10mM Tris-1mM EDTA, pH 9, for 10min and rinsed with Tris-buffered saline (TBS). Antibody binding in the glands was visualized using the Vector VIP chromogen (Vector Laboratories, Burlingame, CA) reagent. Images were taken using an upright Leica DM1000 microscope and Leica DF320 digital camera system. Figures were made using Adobe Photoshop software.

Floden A.M., Sohrabi M., Nookala S., Cao J.J, & Combs C.K. (2020). Salivary Aβ Secretion and Altered Oral Microbiome in Mouse Models of AD. Current Alzheimer research, 17(12), 1133-1144.

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Comprehensive Antibody Panel for Alzheimer's Research

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anti-Aβ/APP 4G8 (mouse mAb, Covance), anti-Aβ/APP 6E10 (mouse mAb, Covance), anti-AβOs scFvA13 and scFvIm3 (ref. 13 (link)), anti-oligomer A11 (ref. 21 (link)) (rabbit pAb Millipore), anti-Aβ (rabbit mAb, Cell Signaling), anti α-Synuclein (mouse mAb, Abcam), anti-APP C-terminal fragment (rabbit pAb, Sigma), anti-APP N-terminal 22C11 (mouse mAb, Millipore), anti-V5 (mouse mAb Invitrogen, and rabbit pAb Sigma), anti-V5-HRP (mouse mAb, Sigma), anti-His tag (mouse mAb Millipore), anti-KDEL (mouse mAb, Assay Design/Stressgen) (kind gift of Prof. R. Sitia, HSR San Raffaele, Milan), anti-mTOR (rabbit pAb, Cell Signaling), anti-phospho-mTOR (rabbit pAb, Cell Signaling), anti-P70S6K (rabbit pAb, Cell Signaling) (kind gift of Dr G. Amadoro, CNR, Rome), anti-phospho-P70S6K (rabbit pAb, Cell Signaling), anti ERK1/2 (rabbit pAb, Cell Signaling), anti phosho-ERK1/2 (rabbit pAb, Cell Signaling), anti phospho-CREB (rabbit pAb, Cell Signaling), anti β-Actin (mouse mAb and rabbit pAb, Sigma), anti-calnexin (rabbit pAb, Sigma), anti-GM130 (mouse mAb, Covance), anti-Golgi 58K (mouse mAb, Sigma), anti-Rab3A (mouse mAb, Sigma), anti-Rab5 (rabbit pAb, Abcam), anti-Rab7 (goat pAb, Santa Cruz), anti-TGN46 (rabbit, pAb), anti-LAMP-1 (rabbit pAb, Abcam). anti-Rab5, anti-Rab7, anti-TGN46 are kind gift of Dr V. Triaca, CNR, Rome.

Meli G., Lecci A., Manca A., Krako N., Albertini V., Benussi L., Ghidoni R, & Cattaneo A. (2014). Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum. Nature Communications, 5, 3867.

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Hippocampal Protein Immunoblotting

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Protein (50–80 μg) from hippocampal tissues lysed in RIPA buffer was loaded onto 10% Tris-Glycine gels and transferred to NC membranes (Millipore). Membranes were incubated with the appropriate primary antibodies (anti-Aβ, 1: 1000, Cell Signaling; GAPDH, 1: 2 500, Ab FRONTIER). GAPDH was used as the loading control. In turn, the membrane was incubated with anti-rabbit or anti-mouse secondary antibodies conjugated to horse radish peroxidase (1: 1000, Invitrogen), and are shown using an enhanced chemiluminescent substrate (Ab FRONTIER).

Ryu J., Hong B.H., Kim Y.J., Yang E.J., Choi M., Kim H., Ahn S., Baik T.K., Woo R.S, & Kim H.S. (2016). Neuregulin-1 attenuates cognitive function impairments in a transgenic mouse model of Alzheimer's disease. Cell Death & Disease, 7(2), e2117-.

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