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5 protocols using methylparaben

1

Formulation and Evaluation of Capsaicin Topical Gel

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Capsaicin was obtained from Plant Lipids Private Limited, Telangana, India. Mineral oil, clove oil, Carbopol 934, Tween 80, Span 80, triethanolamine, propylene glycol, methylparaben, propylparaben, and liquid paraffin were purchased from Loba Chemie, Mumbai. All the other chemicals were procured from HiMedia Lab, Mumbai, India. All the solvents were of High-Performance Liquid Chromatography (HPLC) grade.
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2

Lipid-based Nanoparticle Formulation Development

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MF was gifted by Centaur Pharmaceuticals, Mumbai. Glycerol monostearate (GMS), Compritol 888 ATO, Apifil, Tefose-63 and Emulcire were gifted by Gattefosse India Pvt. Ltd., Mumbai. Cetyl palmitate, Syncrowax-HRC, Syncrowax-HGL were gifted by Croda Chemicals, Mumbai. Stearic acid, Tween-80 from Lubrizol, Mumbai and Phospholipon-80 H, Lipoid S-75 (Soya Lecithin) from Lipoid, Germany were gift samples. Ethanol, Acetone and Carbopol 974p were purchased from Research Lab Fine Chem., industries, Mumbai. Methyl paraben, Propyl paraben, Triethanolamine were purchased from Loba Chemie Pvt. Ltd, Mumbai.
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3

Formulation and Characterization of Pectin-Based Gel

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Edible-grade sucrose was purchased from the local grocery store. Pectin (Sweet King India L.L.P, New Delhi, India), citric acid (Central Drug House (P) Ltd., New Delhi, India), olive oil (Ruchi Food Line, Cuttack, Odisha, India), methylparaben (Loba Chemie, Mumbai, India), and propylparaben (Loba Chemie, Mumbai, India) were purchased. Preservative water (PW) was prepared by dissolving methylparaben (C8H8O3; 0.5% w/w) and propylparaben (C10H12O3; 0.05% w/w) in distilled water at 60 °C.
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4

Antifungal Topical Formulation Development

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Fluconazole (Macklin, China), HPMC E5 LV, methyl paraben, propyl paraben, hydrochloric acid, potassium dihydrogen phosphate (Loba Chemie, India), xanthan gum (Titan Biotech, India), polyethylene sorbitan monooleate (tween 80), clove oil (Molychem, India), sorbitan monolaurate (span 20) (Acros Organics, USA), cinnamon leaf oil (Deo Organics, Sri Lanka), palm olein (raffles oil, Nigeria), methanol (BDH, UK), Strat-M™ membrane, 0.45 μm (Millipore, UK), filter units (0.45 μm), Candida albicans (clinical isolate grown at 37 °C for 24 h on Sabouraud dextrose agar), and deionised water.
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5

Silymarin-based Topical Formulation Development

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The Serum Institute of India Pvt. Ltd. Pune, India supplied silymarin. Carbopol 934, methyl paraben and propyl paraben were purchased from Loba Chemie Pvt. Ltd. Mumbai, India. Propylene glycol and triethanolamine were obtained from SRL Chemicals Pvt. Ltd. Chennai, India.
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