Patients have been investigated on different scanners using 3T and 1,5T (Siemens Symphony Vision, Siemens Symphony Tim, Siemens Avanto, Siemens Sonata, Siemens Verio, Siemens Skyra). Importantly, diffusion weighting was applied with b-values at 0 and 1000 s/mm2 in all patients. For details on the imaging protocol, please see Supplement 1.
Symphony vision
Manufactured by Siemens
Sourced in Germany
Symphony Vision is a specialized laboratory equipment designed for optical microscopy applications. It provides advanced imaging capabilities to support scientific research and analysis. The core function of Symphony Vision is to enable high-resolution visualization and examination of samples using various optical techniques.
Automatically generated - may contain errors
4 protocols using symphony vision
1
Diffusion-Weighted MRI Imaging Protocol
2
MRI Imaging of Ankle and Knee
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MRI was performed on a 1.5-T system (Magnetom Avanto or Symphony Vision, Siemens, Germany) at our department or external radiologic centre. Patients were scanned in the supine position. In five patients a dedicated ankle coil and in 17 patients a knee coil was used. The MR imaging protocol included the following sequences in at least one orientation: T1-weighted TSE images, T2-weighted TSE images, Short-Tau-Inversion-Recovery (STIR) or PD-weighted images with fat-saturation (fluid-sensitive sequences). All images were performed with 3 mm slice-thickness. Additionally a DESS (Dual Echo Steady state) sequence was performed in five patients and in nine patients a T2 MEDIC 3D (Multi Echo Data Image Combination) sequence was performed, both in sagittal orientation.
3
Multi-Modal Imaging of Neuroendocrine Tumors
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Patients have been investigated on different MRI scanners using 3 Tesla (T) and 1,5T (Siemens Symphony Vision (n = 5), Siemens Symphony Tim (n = 26), Siemens Avanto (n = 1), Siemens Sonata (n = 1), Siemens Aera (n = 5), Siemens Skyra (n = 9), GE Optima (n = 1) and Philips Achieva (n = 3)). Importantly, diffusion weighting was applied with b-values at 0 and 1000 s/mm2 in all patients. For details on the imaging protocol, please see Supplement Table 1 . [68Ga]Ga-DOTATOC PET/CT scans were performed at the Department of Nuclear Medicine at Innsbruck Medical University using a dedicated PET/CT system General Electric (GE Discovery 690).[68Ga]Ga was obtained from a [68Ge]/[68Ga] radionuclide generator (Eckert & Ziegler, Berlin; Germany). The described method by Decristoforo et al. [24 (link)] was used for synthesis of [68Ga]Ga-DOTATOC and it was applied intravenously followed by a tracer uptake phase of 60 min. A contrast enhanced low-dose CT scan (Siemens Medical Solutions, Erlangen, Germany) of the head was performed for attenuation correction. The PET scan was acquired in a single bed position and the duration of acquisition was 5 min in emission mode, starting 60 min after application. PET emission data were reconstructed as axial, coronal and sagittal [25 (link)].
4
Rectal MRI Imaging Protocol for Cancer Staging
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Rectal MRI was performed on 1.5-T Siemens Symphony or Siemens Symphony Vision, both running Syngo MR B17 (Siemens, Erlangen, Germany) using a phased-array, 12-channel body coil placed on the pelvis. In concordance with the examination protocol at Haukeland University Hospital, 100–150 ml of ultrasound gel (Eco supergel; Ceracarta, Forlì, Italy) was administered endorectally before imaging 3 (link), in addition to intravenous administration of 20 mg of butylscopolamine bromide (Buscopan; Boehringer Ingelheim, Ingelhim am Rhein, Germany). The MRI protocol consisted of sagittal, coronal and axial T2-weighted turbo spin echo (TSE), high-resolution T2-weighted TSE and axial T1-weighted spin-echo sequences. High-resolution T2-weighted series were angled perpendicular to the long axis of the rectal lesion. The slice thickness in the high-resolution T2 series was 3 mm, with 3-mm spacing indicating no gap between slices 27 (link).
The MRI reports used in the clinical decision process were revisited by a single experienced radiologist (CR) for evaluation of T-stages based on the original MRI report used in the preoperative work-up. Six patients did not undergo MRI examination before surgery, and eight MRI evaluations were inconclusive.
The MRI reports used in the clinical decision process were revisited by a single experienced radiologist (CR) for evaluation of T-stages based on the original MRI report used in the preoperative work-up. Six patients did not undergo MRI examination before surgery, and eight MRI evaluations were inconclusive.
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