3.0 t prisma mr system

Whole-brain images were obtained at the Shandong Provincial Hospital Affiliated to Shandong First Medical University using a Siemens 3.0 T Prisma MR system and a 64-channel head coil for brain scanning. Participants were carefully positioned inside the machine, and foam padding was used to minimize any movement during the scanning process.
T1-weighted whole-brain magnetization-prepared rapid gradient echo (MPRAGE) images were collected to capture anatomical details using the following parameters: TR = 2,530 ms, TE = 2.98 ms, TI = 1,100 ms, FOV = 256 × 256 mm2, in-plane resolution = 256 × 256 mm2, flip angle = 7°, and 192 axial slices. Diffusion imaging was performed using spin–echo echo-planar imaging (SE-EPI). The parameters were set as follows: TR = 5,000 ms, TE = 95 ms, FOV = 224 mm × 224 mm, matrix size 110 × 110, slice thickness 2.0 mm, and 74 slices acquired simultaneously using the simultaneous multislice (SMS) technique with an acceleration factor of 2. Three b-values were used: b = 0, 2000, and 3,000 s/mm², with 64 diffusion gradient directions.

Magnetic resonance imaging scans were performed on a Siemens 3.0 T Prisma MR system at the Shandong Provincial Hospital Affiliated to Shandong First Medical University (Jinan, Shandong, China). We used a 64-channel head coil for whole-brain scanning. Anatomical images were collected using a high-resolution T1-weighted 3-dimensional magnetization-prepared rapid-acquisition gradient-echo pulse sequence with the following acquisition parameters: repetition time (TR) = 2,530 ms, echo time (TE) = 2.98 ms, inversion time (TI) = 1,100 ms, field of view (FOV) = 256 mm, acquisition matrix = 256 × 256 mm², flip angle = 7°, and slice number = 192 slices. During the rs-fMRI scan, a T2*-weighted gradient-echo echo-planar-imaging (GRE-EPI) sequence, which is sensitive to blood oxygen level-dependent (BOLD) signals, with the following parameters was utilized: TR = 2,000 ms, TE = 30 ms, FOV = 220 × 220 mm², matrix size = 64 × 64, slice thickness = 3.5 mm, flip angle = 90°, slices = 33, transverse orientation, and 25% distance factor. A total of 210 whole-brain volumes were acquired. All participants were instructed to relax with their eyes closed and not think of anything in particular during the entire scan session.